This disease grouping is described as ehrlichiosis, used as a collective name for infections caused by obligate intracellular gram-negative bacteria belonging to the genera Ehrlichia, Anaplasma, and Neoehrlichia, family Anaplasmataceae [1]. The chapter cited in the sources specifically includes E. chaffeensis as the agent of human monocytic ehrlichiosis, E. ewingii as the agent of human ewingii ehrlichiosis, and Anaplasma phagocytophilum as the agent of human granulocytic anaplasmosis [1]. It also notes the Panola Mountain ehrlichia, E. canis, and Candidatus neoehrlichia mikurensis in relation to human illness [1].
Disease Profile
BacterialEhrlichiosis and Anaplasmosis
埃立克体病和无形体病
Ehrlichiosis and anaplasmosis are a collective set of infections caused by obligate intracellular gram-negative bacteria in the genera Ehrlichia, Anaplasma, and Neoehrlichia within the family Anaplasmataceae [1]. The source material identifies several human-associated agents, including E. chaffeensis, E. ewingii, and Anaplasma phagocytophilum, and also notes additional species linked to human febrile or severe sepsis-like illness in specific settings [1]. Source-backed detail on timing, prevention practices, and broader surveillance burden is not yet available beyond these organism-level descriptions [1].
The source snippets support a spectrum of human illness ranging from febrile disease to more severe presentations, but they do not provide a full symptom inventory [1]. One cited agent, Candidatus neoehrlichia mikurensis, has been associated with severe sepsis-like conditions in Europe [1]. The Panola Mountain ehrlichia has caused fever in humans in the United States, and E. canis has been identified as an agent of human febrile illness in Venezuela [1]. Source-backed detail on typical symptom progression, complications, or duration is not yet available from the provided material [1].
The available material indicates that human disease occurs in multiple geographic settings, including the United States, Venezuela, and Europe [1]. The sources note that the Panola Mountain ehrlichia has caused fever in humans in the United States, E. canis has been identified in human febrile illness in Venezuela, and Candidatus neoehrlichia mikurensis has caused severe sepsis-like conditions in Europe [1]. Beyond these location-linked examples, the provided snippets do not supply incidence, outbreak trends, or population-level surveillance counts [1]. Source-backed detail on reservoir ecology or seasonal burden is not yet available from the supplied sources [1].
The provided sources define the causative organisms and disease entities but do not describe transmission routes for ehrlichiosis and anaplasmosis [1]. Source-backed detail on vector, reservoir, or person-to-person transmission is not yet available from the supplied material [1].
The provided sources do not identify specific high-risk groups, occupational exposures, age strata, or host factors for ehrlichiosis and anaplasmosis [1]. Source-backed detail on risk groups is not yet available from the supplied material [1].
The source material does not provide prevention recommendations, exposure-control measures, or vaccination information for ehrlichiosis and anaplasmosis [1]. Source-backed detail on preventive practice is not yet available from the supplied sources [1].
In surveillance contexts, this entry should be read as an umbrella designation for infections caused by multiple related intracellular bacteria rather than a single uniform pathogen [1]. The sources emphasize species-level distinctions, including E. chaffeensis, E. ewingii, Anaplasma phagocytophilum, and less common agents such as the Panola Mountain ehrlichia, E. canis, and Candidatus neoehrlichia mikurensis [1]. Because the supplied snippets do not provide standardized case definitions or denominators, source-backed detail on incidence and burden interpretation is not yet available [1].
- 1 Ehrlichiosis and anaplasmosis. Schlossberg's Clinical Infectious Disease. 2021. doi: 10.1093/med/9780190888367.003.0169. DOI: https://doi.org/10.1093/med/9780190888367.003.0169
- 2 Ehrlichiosis and anaplasmosis. Clinical Infectious Disease. 2015. doi: 10.1017/cbo9781139855952.193. DOI: https://doi.org/10.1017/cbo9781139855952.193
- 3 Ehrlichiosis/Anaplasmosis. Hematopathology. 2013. doi: 10.1016/b978-1-4377-1758-7.00021-x. DOI: https://doi.org/10.1016/b978-1-4377-1758-7.00021-x
- 4 Ehrlichiosis/Anaplasmosis. Control of Communicable Diseases. 2019. doi: 10.2105/ccdml.2868.052. DOI: https://doi.org/10.2105/ccdml.2868.052
- 5 Wikidata contributors. Ehrlichiosis and Anaplasmosis in Dogs and Cats [Internet]. Wikidata. cited 20 May 2026. Available from: https://www.wikidata.org/wiki/Q34142591
- 6 Wikipedia contributors. Heartland virus [Internet]. Wikipedia. cited 20 May 2026. Available from: https://en.wikipedia.org/wiki/Heartland_virus
Dataset Archive
Supplementary Data | Multi-country disease dataset
Machine-readable multi-country disease dataset (JSON/CSV) with source metadata.
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