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Disease Profile

Viral

Hantavirus syndrome

汉他病毒症候群

Hantavirus syndrome is presented in the source material as a pulmonary hantavirus syndrome and cardiopulmonary hantavirus syndrome, with scholarly references identifying it under the broader label of hantavirus pulmonary syndrome [1][2][3][4][5][6]. The available evidence is limited but indicates that the syndrome was recognized among lower respiratory tract infections and has been discussed in clinical and reference sources over time [1][3][5]. Source-backed detail on the full syndrome spectrum is not yet available beyond these designations [1][2].

Definition

The source set supports hantavirus syndrome as a viral disease concept centered on hantavirus pulmonary syndrome, also referred to in one review as cardiopulmonary hantavirus syndrome [1][2][3][4][5][6]. It is described in a pneumonia-focused review among newly recognized causes of lower respiratory tract infection [1]. Source-backed detail on the etiologic species, formal case definition, or broader classification beyond this pulmonary/cardiopulmonary framing is not yet available [1][2].

Clinical features

The only explicit clinical characterization in the sources is that the syndrome is pulmonary or cardiopulmonary, placing it within lower respiratory tract disease [1][2]. One review grouped it with other newly recognized agents causing lower respiratory tract infections [1]. The source material does not provide a symptom sequence, severity pattern, complications, or timing of progression beyond reporting 105 recognized patients and a mortality of 52% in one summary [1]. Source-backed detail on additional clinical manifestations is not yet available [1][2].

Epidemiology

One PubMed abstract reports 105 recognized patients in the USA and Canada, with mortality reported at 52% [1]. The same source links the syndrome to the deermouse, identified there as the homeland of Peromiscus maniculatus, suggesting an association with that ecological context [1]. Beyond this North American recognition and the single mortality figure, the provided sources do not supply incidence trends, outbreak chronology, or broader geographic distribution [1][2]. Source-backed detail on surveillance burden outside this summary is not yet available [1].

Transmission

The provided sources do not state a transmission route, exposure mechanism, or person-to-person spread pattern for hantavirus syndrome [1][2][3][4][5][6]. The only ecological clue is the reference to the deermouse, Peromiscus maniculatus, in connection with the recognized cases [1]. Source-backed detail on how human infection is acquired is not yet available [1].

Risk groups

The source set does not identify patient risk groups by age, occupation, comorbidity, or other demographic category [1][2][3][4][5][6]. The only exposure-related clue is the association with Peromiscus maniculatus in the cited review [1]. Source-backed detail on high-risk groups is not yet available.

Prevention

No explicit prevention measures, exposure controls, vaccination information, or public-health recommendations are given in the supplied sources [1][2][3][4][5][6]. The material is limited to disease naming and brief epidemiologic or bibliographic notes [1][3][5]. Source-backed detail on prevention is not yet available [1][2].

Surveillance note

In surveillance contexts, the available material supports reading hantavirus syndrome as a recognized pulmonary or cardiopulmonary hantavirus entity within lower respiratory tract infection monitoring [1][2]. The sources also indicate that it has been sufficiently notable to appear in reference works and chapter-level clinical discussions over multiple years [3][4][5][6]. Because the evidence base here is sparse, surveillance interpretation should remain conservative and limited to the documented pulmonary/cardiopulmonary framing, the reported 105 recognized patients, and the 52% mortality noted in one review [1].

References
  1. 1 Regamey C et al. [Various new pathogens in pneumonia]. Schweiz Med Wochenschr. 1995 Nov 11. PMID: 8525335. PubMed: https://pubmed.ncbi.nlm.nih.gov/8525335/
  2. 2 Sotomayor P V et al. [Diagnosis and treatment of cardiopulmonary hantavirus syndrome: Chile-2007]. Rev Chilena Infectol. 2009 Feb. PMID: 19350164. PubMed: https://pubmed.ncbi.nlm.nih.gov/19350164/
  3. 3 Hantavirus Pulmonary Syndrome. Red Book (2018). 2018. doi: 10.1542/9781610021470-part03-hantavirus_pulmonary. DOI: https://doi.org/10.1542/9781610021470-part03-hantavirus_pulmonary
  4. 4 Hantavirus Pulmonary Syndrome. Community-Acquired Pneumonia. 2002. doi: 10.1007/0-306-46834-4_40. DOI: https://doi.org/10.1007/0-306-46834-4_40
  5. 5 Hantavirus Pulmonary Syndrome. Red Book: 2024–2027 Report of the Committee on Infectious Diseases. 2024. doi: 10.1542/9781610027373-s3_008_002. DOI: https://doi.org/10.1542/9781610027373-s3_008_002
  6. 6 Hantavirus Pulmonary Syndrome. Red Book: 2024–2027 Report of the Committee on Infectious Diseases. 2024. doi: 10.1542/9781610027359-s3_008_002. DOI: https://doi.org/10.1542/9781610027359-s3_008_002
Coding Register
ICD-10
ICD-11
Key Statistics
Total cases
0
Peak month
Coverage
0 reporting countries · —

Dataset Archive

Supplementary Data | Multi-country disease dataset

Machine-readable multi-country disease dataset (JSON/CSV) with source metadata.

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0
Data Version
2026-06-20
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Included metadata
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