The entity denotes a SINAN surveillance concept for anti-rabies care administered after exposure, as defined by the Brazil Ministry of Health notification system [3]. It reflects post-exposure prophylactic measures against rabies virus infection rather than a clinical disease category [4].
Disease overview
Other Evidence-backed information EN 1/6 applicable sections · ZH 1/6 applicable sections Updated Oct 23, 2026
Rabies post-exposure prophylaxis is a public-health intervention applied after potential exposure to rabies virus, encompassing wound care, vaccination, and immunoglobulin in severe exposures [1]. Approximately 15 million people receive such prophylaxis each year worldwide [2]. Surveillance systems such as Brazil's SINAN record this care as a notifiable health event following exposure [3].
Read the full clinical and epidemiological profile 2
- 1 Kessels J et al. Rabies post-exposure prophylaxis: A systematic review on abridged vaccination schedules and the effect of changing administration routes during a single course. Vaccine. 2019 Oct 3. PMID: 30737043. doi: 10.1016/j.vaccine.2019.01.041. PubMed: https://pubmed.ncbi.nlm.nih.gov/30737043/
- 2 Singh R et al. Rabies - epidemiology, pathogenesis, public health concerns and advances in diagnosis and control: a comprehensive review. Vet Q. 2017 Dec. PMID: 28643547. doi: 10.1080/01652176.2017.1343516. PubMed: https://pubmed.ncbi.nlm.nih.gov/28643547/
- 3 Brazil Ministry of Health SINAN. SINAN registry entity: Rabies post-exposure prophylaxis [Internet]. cited 23 Oct 2026. Available from: https://www.gov.br/saude/pt-br/composicao/svsa/sistemas-de-informacao/sinan
- 4 Ilina EN et al. Recombinant Monoclonal Antibodies for Rabies Post-exposure Prophylaxis. Biochemistry (Mosc). 2018 Jan. PMID: 29534663. doi: 10.1134/S0006297918010017. PubMed: https://pubmed.ncbi.nlm.nih.gov/29534663/
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Research Radar
Recent related research
Comparing recombinant human rabies monoclonal antibody (ormutivimab) with human rabies immunoglobulin (HRIG) for postexposure prophylaxis: A phase III, randomized, double-blind, non-inferiority trial
International Journal of Infectious Diseases
Progress towards dog-mediated rabies elimination in PR China: a scoping review
Infectious Diseases of Poverty
Fatal Human Rabies Infection With Suspected Host-Mediated Failure of Post-Exposure Prophylaxis Following a Recognized Zoonotic Exposure—Minnesota, 2021
Clinical Infectious Diseases
On the path to rabies elimination: The need for risk assessments to improve administration of post-exposure prophylaxis
Vaccine
Rabies post-exposure prophylaxis initiation and adherence among patients in Vietnam, 2014–2016
Vaccine
Showing 5 of 6 related publications.
Literature links are provided for discovery and do not alter or validate the surveillance series above.
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