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Rabies post-exposure prophylaxis

狂犬病暴露后处置

Evidence-backed informationEN 1/6 applicable sections · ZH 1/6 applicable sectionsUpdated Sep 3, 2026

Mass bat exposure (MBE) events, in which groups of individuals are potentially exposed to rabies through contact with bats, represent a distinct public-health scenario requiring post-exposure prophylaxis (PEP) decisions [1]. Rabies is a fatal, progressive neurological zoonosis caused by rabies virus of the genus Lyssavirus and family Rhabdoviridae, affecting all warm-blooded animals worldwide and endemic in many countries, with over 60,000 deaths annually and approximately 15 million people receiving PEP each year [2]. MBE events have occurred in diverse settings including camping sites, domestic flights, neonatal intensive care units, and dormitories, with potential exposures ranging from five to over 1,400 people [1].

Read the full clinical and epidemiological profile2
Surveillance entity definition

The SINAN (Sistema de Informação de Agravos de Notificação) registry entry "Rabies post-exposure prophylaxis" reflects Brazil's national surveillance concept for anti-rabies care administered after potential exposure, as defined by the Brazil Ministry of Health [3]. This surveillance entity captures the notification and follow-up of PEP events rather than clinical rabies disease itself. Rabies is a fatal zoonotic neurological infection caused by rabies virus of the genus Lyssavirus and family Rhabdoviridae [2].

References
  1. 1Choe YJ et al. Post-exposure rabies prophylaxis for mass bat exposures: Case series and systematic review. Zoonoses Public Health. 2020 Jun. PMID: 32347667. doi: 10.1111/zph.12706.PubMed: https://pubmed.ncbi.nlm.nih.gov/32347667/
  2. 2Singh R et al. Rabies - epidemiology, pathogenesis, public health concerns and advances in diagnosis and control: a comprehensive review. Vet Q. 2017 Dec. PMID: 28643547. doi: 10.1080/01652176.2017.1343516.PubMed: https://pubmed.ncbi.nlm.nih.gov/28643547/
  3. 3Brazil Ministry of Health SINAN. SINAN registry entity: Rabies post-exposure prophylaxis [Internet]. cited 3 Sept 2026.Available from: https://www.gov.br/saude/pt-br/composicao/svsa/sistemas-de-informacao/sinan
Coding Register
ICD-10
Z20.3
ICD-11
Key Statistics
Total cases
9.7M
Peak month
2025-01
Coverage
1 reporting countries · 2006-01-01 → 2026-05-01

Coverage

Reporting countries and regions

1 location

Monthly patterns over time

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Literature links are provided for discovery and do not alter or validate the surveillance series above.

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Rows199
Updated2026-09-01
Coverage
Partitions5
Source0 series · 0 observations
Official sourcesAuthority, cadence, notes1
Brazil

Brazil DATASUS SINAN

Brazil

Source
monthlyftp_dbc

Brazil Ministry of Health DATASUS/SINAN public DBC microdata aggregated to national monthly notification counts.

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