GIDS Research Radar ยท Singapore https://globalinfectiousdisease.com/research/ Published infectious-disease literature filtered to Singapore. en Wed, 09 Sep 2026 07:02:01 GMT Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore: a randomised, controlled, double-blind, single-centre, phase 4 clinical trial https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00062-9-581e6928/ https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00062-9-581e6928/ Sat, 01 Aug 2026 00:00:00 GMT Findings address whether enhanced antigen dose or non-egg production platforms can improve immunogenicity against A(H3N2) strains, which have been associated with reduced effectiveness of egg-derived vaccines. Influenza Vaccination Treatment Randomised controlled trial Health system resilience in managing the COVID-19 pandemic: lessons from Singapore https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2020-003317-ad1f1f3a/ https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2020-003317-ad1f1f3a/ Wed, 16 Sep 2020 00:00:00 GMT The discussion underscores how coordinated administrative actions and targeted intervention protocols can stabilize healthcare operations during sudden epidemic waves, informing future emergency planning. COVID-19 Outbreak investigation Transmission dynamics Health policy Journal article Estimating the generation interval for coronavirus disease (COVID-19) based on symptom onset data, March 2020 https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2020-25-17-2000257-627c7d90/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2020-25-17-2000257-627c7d90/ Thu, 30 Apr 2020 00:00:00 GMT The abstract indicates that substantial estimated pre-symptomatic transmission may limit reliance on case finding and contact tracing alone for outbreak control. It also reports that detailed contact-tracing information is important when estimating these transmission quantities from outbreak data. COVID-19 SARS Influenza Transmission dynamics Outbreak investigation Surveillance Journal article Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore https://globalinfectiousdisease.com/research/articles/10-1001-jama-2020-3204-7b95728d/ https://globalinfectiousdisease.com/research/articles/10-1001-jama-2020-3204-7b95728d/ Tue, 21 Apr 2020 00:00:00 GMT This is early peer-reviewed clinical and epidemiologic information on SARS-CoV-2 in Singapore. It may help contextualize published outbreak literature on presentation, specimen positivity, and hospital-level care needs. COVID-19 SARS Treatment Transmission dynamics Outbreak investigation Journal article Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-20-30528-6-40462196/ https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-20-30528-6-40462196/ Sun, 01 Mar 2020 00:00:00 GMT SARS-CoV-2 demonstrated transmissibility in community settings, indicating that countries with high travel volume from China before restrictions would likely experience local clusters. Enhanced surveillance and contact tracing were identified as essential to prevent widespread community transmission. COVID-19 SARS Outbreak investigation Surveillance Transmission dynamics Journal article Intense interseasonal influenza outbreaks, Australia, 2018/19 https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2019-24-33-1900421-27c620d3/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2019-24-33-1900421-27c620d3/ Thu, 15 Aug 2019 00:00:00 GMT These unprecedented interseasonal outbreaks followed a mild 2018 influenza season and highlight the need for year-round influenza surveillance even in temperate climates with strong seasonal patterns. The event underscores that interseasonal influenza activity can reach levels comparable to or exceeding typical seasonal peaks. Influenza Outbreak investigation Climate and environment Surveillance Journal article Prediction of Dengue Incidence Using Search Query Surveillance https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001258-55131984/ https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001258-55131984/ Tue, 02 Aug 2011 00:00:00 GMT Search-query surveillance offers a readily available and cost-effective tool that may support dengue monitoring in settings where traditional surveillance infrastructure is limited. Dengue Influenza Surveillance Transmission dynamics Treatment Journal article