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  <title>GIDS Research Radar · Uganda</title>
  <link>https://globalinfectiousdisease.com/research/</link>
  <description>Published infectious-disease literature filtered to Uganda.</description>
  <language>en</language>
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  <lastBuildDate>Wed, 09 Sep 2026 07:02:01 GMT</lastBuildDate>
  <item>
    <title>Field Investigation of the Bundibugyo Ebola Virus Disease (BDBV) Outbreak in Ituri Province, Democratic Republic of the Congo: Challenges, Strategies, and Priority Actions for Outbreak Control—An Outbreak Investigation Review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3390-idr18050100-0286cca8/</link>
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    <pubDate>Tue, 08 Sep 2026 00:00:00 GMT</pubDate>
    <description>The abstract frames the outbreak as a major Ebola control challenge in a conflict-affected and socially complex setting. It identifies surveillance, contact tracing, laboratory capacity, IPC, clinical care, risk communication, misinformation management, and community trust as priority areas for outbreak response and preparedness.</description>
    <category>Ebola</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Outbreak investigation</category>
  </item>
  <item>
    <title>Implementing an intra outbreak ring vaccination clinical trial for Sudan Ebola virus disease within four days of outbreak notification in Uganda.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1080-22221751-2026-2731496-7d1abb29/</link>
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    <pubDate>Mon, 07 Sep 2026 00:00:00 GMT</pubDate>
    <description>The four-day turnaround provides a replicable blueprint for rapid medical countermeasure evaluation during future outbreaks in settings with heightened Ebola Virus Disease threat. The approach demonstrates that prepositioned protocols, established infrastructure, and trained personnel can dramatically compress trial activation timelines.</description>
    <category>Ebola</category>
    <category>Vaccination</category>
    <category>Outbreak investigation</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Multiple local PfDHFR I164L haplotype expansions drive Plasmodium falciparum antifolate resistance in Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-76826-4-43defbd3/</link>
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    <pubDate>Fri, 04 Sep 2026 00:00:00 GMT</pubDate>
    <description>The findings are relevant to malaria control because the studied mutations are associated with antifolate resistance, and the paper describes PfDHFR I164L as conferring higher pyrimethamine resistance. The results indicate that resistance-related patterns may vary across locations using sulfadoxine-pyrimethamine chemoprevention.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Regional signals preceding the 2026 Bundibugyo virus disease outbreak</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-108862-d477aad3/</link>
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    <pubDate>Tue, 01 Sep 2026 00:00:00 GMT</pubDate>
    <description>Findings point to potential deficiencies in protocols for managing cases that test negative for standard pathogens.</description>
    <category>Hemorrhagic Fever</category>
    <category>Ebola</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-imj-2026-100270-6c5ddd42/</link>
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    <pubDate>Tue, 01 Sep 2026 00:00:00 GMT</pubDate>
    <description>The document underscores urgent requirements for novel prophylactic and therapeutic development while demonstrating how transnational coordination mechanisms can address complex outbreak environments marked by infrastructure deficits and social friction.</description>
    <category>Ebola</category>
    <category>Outbreak investigation</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Implications of edge cases for antimicrobial susceptibility predictions for rifampin, delamanid, and pretomanid with the WHO &lt;i&gt;Mycobacterium tuberculosis&lt;/i&gt; mutation catalog.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1128-spectrum-01821-26-8bd430ba/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>The WHO mutation catalog is increasingly used for clinical decision-making, and false-resistant predictions for rifampin, delamanid, and pretomanid can lead to inappropriate treatment adjustments, highlighting the need for systematic quality control.</description>
    <category>Tuberculosis</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>From visceral to visible: A systematic review and meta-analysis of post-kala-azar dermal leishmaniasis incidence, risk factors, and treatment outcomes in Eastern Africa</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0014666-afa1362a/</link>
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    <pubDate>Tue, 18 Aug 2026 00:00:00 GMT</pubDate>
    <description>Consolidating regional outcome data helps identify modifiable therapeutic variables and highlights gaps in longitudinal tracking necessary for coordinated control initiatives.</description>
    <category>Kala-azar</category>
    <category>Leishmaniasis</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Water, Sanitation and Hygiene in Ebola Preparedness and Response in South Sudan, Uganda and the Democratic Republic of the Congo: A Scoping Review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-19044-esipreprint-8-2026-p97-24674607/</link>
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    <pubDate>Sat, 08 Aug 2026 00:00:00 GMT</pubDate>
    <description>Embedding durable environmental services, practical staff education, community outreach, and regional cooperation into standard health budgets could improve future epidemic resilience.</description>
    <category>Ebola</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>COVID-19 vaccination among people with HIV in Uganda: lessons from a high-risk group with high vaccine uptake for the next pandemic</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128912-61c4c107/</link>
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    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>Sustaining elevated protection levels in this clinical subgroup requires targeted communication strategies that address safety perceptions and counteract inaccurate health information.</description>
    <category>COVID-19</category>
    <category>AIDS</category>
    <category>Vaccination</category>
    <category>Vaccine safety</category>
    <category>Treatment</category>
    <category>Cohort study</category>
  </item>
  <item>
    <title>Bundibugyo Virus Disease Outbreak and Cross-Border Response in the Democratic Republic of the Congo and Uganda, May-June 2026.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-7759-cureus-112459-e636cd4f/</link>
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    <pubDate>Sat, 11 Jul 2026 00:00:00 GMT</pubDate>
    <description>The discussion underscores the importance of adaptable international cooperation and localized preparedness when addressing novel hemorrhagic fever threats lacking established medical interventions.</description>
    <category>Ebola</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>Travel medicine</category>
    <category>Commentary</category>
  </item>
  <item>
    <title>Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development Accelerates.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-12659-msm-954627-55727a36/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-12659-msm-954627-55727a36/</guid>
    <pubDate>Wed, 01 Jul 2026 00:00:00 GMT</pubDate>
    <description>The discussion emphasizes the operational necessity of deploying medical countermeasures during declared crises, especially when conventional clinical management proves insufficient for lowering death rates.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>Vaccination</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Commentary</category>
  </item>
  <item>
    <title>It&apos;s not just virology: The Bundibugyo Ebola outbreak in the Democratic Republic of the Congo and Uganda demands a wider public health response.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-29063-ajrh2026-v30i13-1-3cdaa5c3/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-29063-ajrh2026-v30i13-1-3cdaa5c3/</guid>
    <pubDate>Wed, 01 Jul 2026 00:00:00 GMT</pubDate>
    <description>The manuscript calls for integrating socioeconomic and environmental interventions into standard outbreak management frameworks to improve long-term resilience.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>Outbreak investigation</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Closing Critical Gaps in the 2026 Bundibugyo Ebola Response: Five Actionable Priorities.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-7759-cureus-111921-46b92e7b/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-7759-cureus-111921-46b92e7b/</guid>
    <pubDate>Wed, 01 Jul 2026 00:00:00 GMT</pubDate>
    <description>Outlining rapid, scalable measures deployable through current infrastructure, the discussion highlights how targeted operational shifts may improve immediate outbreak management while strengthening long-term regional readiness.</description>
    <category>Ebola</category>
    <category>Surveillance</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Vaccination</category>
    <category>Genomic epidemiology</category>
    <category>Diagnostics</category>
    <category>One Health</category>
    <category>Commentary</category>
  </item>
  <item>
    <title>Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-74737-y-6f2038f6/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-74737-y-6f2038f6/</guid>
    <pubDate>Fri, 26 Jun 2026 00:00:00 GMT</pubDate>
    <description>The work addresses an urgent regional challenge by quantifying how strategic antimalarial policy adjustments could preserve drug efficacy and reduce clinical failures over a six-year timeframe.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Transmission dynamics</category>
    <category>Health policy</category>
    <category>Mathematical modelling</category>
  </item>
  <item>
    <title>High frequency of HIV-1 drug resistance among individuals with persistent low-level viremia during first-line antiretroviral therapy in Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13774-w-8756edff/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13774-w-8756edff/</guid>
    <pubDate>Tue, 16 Jun 2026 00:00:00 GMT</pubDate>
    <description>The findings suggest that drug resistance genotyping should be considered for individuals on first-line therapy with detectable persistent low-level viremia. Targeted interventions for youth may improve HIV control outcomes.</description>
    <category>AIDS</category>
    <category>Treatment</category>
    <category>Cross-sectional study</category>
  </item>
  <item>
    <title>Assessment of Risk to the U.S. Population from the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7522e2-ab9bf047/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7522e2-ab9bf047/</guid>
    <pubDate>Thu, 11 Jun 2026 00:00:00 GMT</pubDate>
    <description>The evaluation outlines domestic preparedness thresholds and clarifies resource requirements for managing imported viral hemorrhagic fever scenarios.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Willingness to receive Ebola vaccines among pregnant and lactating women in Kampala, Uganda: insights from a post-outbreak cross-sectional study</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128737-43c54279/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128737-43c54279/</guid>
    <pubDate>Mon, 01 Jun 2026 00:00:00 GMT</pubDate>
    <description>Results underscore the necessity of incorporating maternal populations into emergency immunization protocols while simultaneously deploying targeted educational initiatives to mitigate safety concerns and knowledge deficits.</description>
    <category>Ebola</category>
    <category>COVID-19</category>
    <category>Hemorrhagic Fever</category>
    <category>Vaccination</category>
    <category>Outbreak investigation</category>
    <category>Climate and environment</category>
    <category>Cross-sectional study</category>
  </item>
  <item>
    <title>Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciag077-760e929b/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciag077-760e929b/</guid>
    <pubDate>Tue, 10 Mar 2026 00:00:00 GMT</pubDate>
    <description>Tongue swab-based molecular testing achieved non-inferior diagnostic yield compared to sputum-based methods and may offer a cost-efficient alternative where sputum collection is difficult or where smear microscopy remains the primary diagnostic approach.</description>
    <category>Tuberculosis</category>
    <category>Diagnostics</category>
    <category>Cross-sectional study</category>
  </item>
  <item>
    <title>Investigating the Sudan virus outbreak in Uganda through the deployment of a mobile laboratory</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-12556-8-67e9ba93/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-12556-8-67e9ba93/</guid>
    <pubDate>Fri, 16 Jan 2026 00:00:00 GMT</pubDate>
    <description>Co-locating a mobile laboratory with the treatment unit shortened diagnostic turnaround, supported national data-driven decision-making, and enabled follow-up surveillance relevant to outbreak containment and survivor counselling.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>Rift Valley fever</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Circulating prothymosin alpha and immunoglobulin G3 in acute rheumatic fever and rheumatic heart disease: A case-control study.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ahjo-2025-100630-7f7211ab/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-ahjo-2025-100630-7f7211ab/</guid>
    <pubDate>Mon, 29 Sep 2025 00:00:00 GMT</pubDate>
    <description>Findings are relevant to the lack of specific diagnostic tests for acute rheumatic fever and rheumatic heart disease in low-resource settings, where these diseases impose the greatest burden.</description>
    <category>Rheumatic fever</category>
    <category>Diagnostics</category>
    <category>Case-control study</category>
  </item>
  <item>
    <title>Mpox in Africa: What we know and what is still lacking</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013148-060ab7b4/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013148-060ab7b4/</guid>
    <pubDate>Thu, 12 Jun 2025 00:00:00 GMT</pubDate>
    <description>The authors argue Mpox has the potential to disrupt health systems and undermine progress toward the 2030 sustainable development goals, calling for financial and human resource support from countries both within and outside Africa.</description>
    <category>Monkeypox</category>
    <category>Smallpox</category>
    <category>Surveillance</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Vaccination</category>
    <category>Climate and environment</category>
    <category>One Health</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Policy uptake and implementation of the RTS,S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years following the WHO recommendation</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2023-014719-e90724cb/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2023-014719-e90724cb/</guid>
    <pubDate>Tue, 30 Apr 2024 00:00:00 GMT</pubDate>
    <description>Twenty of thirty countries applying for vaccine support received financial approval from the Global Alliance for Vaccines and Immunization as of March 2024, demonstrating widespread interest. However, limited RTS,S/AS01 availability prevents some approved countries from receiving required doses, raising vaccine equity concerns.</description>
    <category>Malaria</category>
    <category>Vaccination</category>
    <category>Health policy</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Sudan virus disease outbreak in Uganda: urgent research gaps</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2022-010982-b4e8d0a7/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2022-010982-b4e8d0a7/</guid>
    <pubDate>Fri, 30 Dec 2022 00:00:00 GMT</pubDate>
    <description>The authors highlight limited SUDV research investment, no licensed vaccine or therapeutics, ongoing transmission across regions of Uganda including the capital, and an uncertain case count as drivers of concern.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>COVID-19</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>One Health</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Artemisinin - Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014–2016</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3201-eid2404-170141-d3c245aa/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3201-eid2404-170141-d3c245aa/</guid>
    <pubDate>Sun, 01 Apr 2018 00:00:00 GMT</pubDate>
    <description>Because approximately 90% of malaria cases occur in Africa, the emergence of possibly artemisinin-resistant P. falciparum in Uganda represents a public health concern. The authors advocate large-scale surveillance to inform treatment outcomes and regional malaria control.</description>
    <category>Malaria</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-14-62385-0-38ad575b/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-14-62385-0-38ad575b/</guid>
    <pubDate>Wed, 01 Apr 2015 00:00:00 GMT</pubDate>
    <description>The paper is relevant to vaccine development for two high-fatality viral diseases and to early clinical evaluation of candidate vaccines in an African setting. It also provides context for later development work on Ebola vaccine antigens.</description>
    <category>Ebola</category>
    <category>Treatment</category>
    <category>Vaccination</category>
    <category>Outbreak investigation</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Understanding the dynamics of Ebola epidemics</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1017-s0950268806007217-bbe032f1/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1017-s0950268806007217-bbe032f1/</guid>
    <pubDate>Tue, 26 Sep 2006 00:00:00 GMT</pubDate>
    <description>The findings suggest that rapid hospitalization is a key intervention for reducing Ebola epidemic size, providing quantitative support for containment strategies.</description>
    <category>Ebola</category>
    <category>Hemorrhagic Fever</category>
    <category>COVID-19</category>
    <category>Transmission dynamics</category>
    <category>Treatment</category>
    <category>Outbreak investigation</category>
    <category>Mathematical modelling</category>
  </item>
  <item>
    <title>New Measles Genotype, Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3201-eid1110-050431-bed53673/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3201-eid1110-050431-bed53673/</guid>
    <pubDate>Sat, 01 Oct 2005 00:00:00 GMT</pubDate>
    <description>The abstract states that the sequence data may improve molecular epidemiologic work for describing measles transmission patterns in eastern Africa.</description>
    <category>Measles</category>
    <category>Influenza</category>
    <category>Genomic epidemiology</category>
    <category>Outbreak investigation</category>
    <category>Genomic study</category>
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