https://globalinfectiousdisease.com/research/ Published infectious-disease literature filtered to South Africa. en Wed, 09 Sep 2026 07:02:01 GMT https://globalinfectiousdisease.com/research/articles/10-1186-s41936-026-00636-9-6fc68508/ https://globalinfectiousdisease.com/research/articles/10-1186-s41936-026-00636-9-6fc68508/ Wed, 26 Aug 2026 00:00:00 GMT The findings indicate that molecular testing may complement morphological identification in mosquito vector monitoring in the reported Limpopo setting. The abstract states that using additional, more variable markers alongside morphology could improve species discrimination and support malaria-control programmes. Malaria Genomic epidemiology Surveillance Transmission dynamics Genomic study https://globalinfectiousdisease.com/research/articles/10-1093-shm-hkag069-014e76ec/ https://globalinfectiousdisease.com/research/articles/10-1093-shm-hkag069-014e76ec/ Thu, 20 Aug 2026 00:00:00 GMT The article highlights how segregation, poverty, and political structures can obstruct TB treatment, surveillance, and social-health interventions, even when curative medical technology is available. Tuberculosis Surveillance Journal article https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-75909-6-e2e28e53/ https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-75909-6-e2e28e53/ Sat, 25 Jul 2026 00:00:00 GMT The findings suggest that biomarkers developed for symptomatic tuberculosis triage should not be directly adopted for community-based asymptomatic screening without additional optimization. Tuberculosis Diagnostics Health policy Journal article https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13967-3-3cb8b7c0/ https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13967-3-3cb8b7c0/ Tue, 21 Jul 2026 00:00:00 GMT The findings suggest potential benefits of STI screening using diagnostic tests that enable timely treatment of curable STIs during pregnancy to reduce adverse pregnancy outcomes. Gonorrhea Diagnostics Treatment Journal article https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7510a1-514d0b54/ https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7510a1-514d0b54/ Thu, 19 Mar 2026 00:00:00 GMT Persistent monitoring remains necessary to evaluate whether genetic shifts could diminish immunity from past exposures or shots, especially considering the ongoing global disease burden. SARS COVID-19 Surveillance Vaccination Genomic epidemiology Travel medicine Journal article https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101293-2e1d7dc7/ https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101293-2e1d7dc7/ Sun, 01 Mar 2026 00:00:00 GMT Authors emphasize the necessity of prioritizing systematic monitoring for resistance to maintain effective treatment protocols. Elevated resistance levels in certain subgroups underscore the importance of updated diagnostic and therapeutic approaches. Tuberculosis Surveillance Antimicrobial resistance Diagnostics Treatment Cohort study https://globalinfectiousdisease.com/research/articles/10-1016-s2666-5247-23-00172-6-4080c24a/ https://globalinfectiousdisease.com/research/articles/10-1016-s2666-5247-23-00172-6-4080c24a/ Fri, 01 Dec 2023 00:00:00 GMT The findings demonstrate substantial bedaquiline-resistance gain in programmatically treated patients and provide evidence of bedaquiline-resistant strain transmission. The authors emphasize that routine drug susceptibility testing should urgently accompany scale-up of novel tuberculosis drugs, though rapid testing remains challenging due to genetic variant diversity. Tuberculosis Antimicrobial resistance Transmission dynamics Treatment Cohort study https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2021-007136-90531e37/ https://globalinfectiousdisease.com/research/articles/10-1136-bmjgh-2021-007136-90531e37/ Fri, 08 Apr 2022 00:00:00 GMT The findings indicate that primary healthcare clinics may contribute to community tuberculosis burden in the modeled setting and that clinic infection-prevention measures could have effects beyond healthcare workers and patients. These implications are model-based estimates for the study community and period, not observed outcome measurements. Tuberculosis Transmission dynamics Climate and environment Antimicrobial resistance Treatment Journal article https://globalinfectiousdisease.com/research/articles/10-1186-s12879-021-06604-8-bc0b9fea/ https://globalinfectiousdisease.com/research/articles/10-1186-s12879-021-06604-8-bc0b9fea/ Wed, 08 Sep 2021 00:00:00 GMT The findings demonstrate that physical distancing regulations substantially reduced extra-household contact in rural South Africa during the epidemic peak. However, persistent intergenerational contact within households represented a potential limitation in protecting older adults from infection. COVID-19 SARS Transmission dynamics Outbreak investigation Climate and environment Cross-sectional study https://globalinfectiousdisease.com/research/articles/10-1038-s41586-021-03398-2-abd2039f/ https://globalinfectiousdisease.com/research/articles/10-1038-s41586-021-03398-2-abd2039f/ Mon, 08 Mar 2021 00:00:00 GMT The abstract frames these variants as relevant to COVID-19 interventions because some authorized and developing therapies and vaccines targeted earlier SARS-CoV-2 forms. The reported neutralization differences are relevant to treatment and vaccination considerations at a population-health level. COVID-19 SARS Vaccination Treatment Transmission dynamics Journal article https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-19-30297-x-692c94da/ https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-19-30297-x-692c94da/ Mon, 01 Jul 2019 00:00:00 GMT Findings suggest emerging non-vaccine serotypes may be shaped by local antibiotic-selective pressures, highlighting the need for continued genomic surveillance to inform future vaccine design. Invasive pneumococcal disease Genomic epidemiology Antimicrobial resistance Surveillance Vaccination Genomic study https://globalinfectiousdisease.com/research/articles/10-1017-s0950268817000565-5a0f64c0/ https://globalinfectiousdisease.com/research/articles/10-1017-s0950268817000565-5a0f64c0/ Thu, 30 Mar 2017 00:00:00 GMT The findings suggest that HEV transmission in this population may differ from the classical oro-faecal route associated with genotypes 1 and 2, potentially reflecting zoonotic transmission via dietary meat consumption and socio-economic differences. Understanding transmission routes is important for prevention strategies. Hepatitis E Gastroenteritis Hepatitis A Transmission dynamics Outbreak investigation One Health Journal article https://globalinfectiousdisease.com/research/articles/10-1111-1469-0691-12415-8d8563f9/ https://globalinfectiousdisease.com/research/articles/10-1111-1469-0691-12415-8d8563f9/ Sun, 01 Jun 2014 00:00:00 GMT The findings suggest that successful transmission of F15/LAM4/KZN strains during the Tugela Ferry outbreak may be explained by drug-resistance mutations that impose little or no fitness cost. The persistence of viable drug-resistant strains at low concentrations in mixed populations could support acquisition of additional resistance mutations or evolution of compensatory mechanisms, with implications for MDR and XDR-TB control strategies. Tuberculosis Antimicrobial resistance Outbreak investigation Transmission dynamics Journal article https://globalinfectiousdisease.com/research/articles/10-2471-blt-12-106807-e1a8b381/ https://globalinfectiousdisease.com/research/articles/10-2471-blt-12-106807-e1a8b381/ Mon, 19 Nov 2012 00:00:00 GMT Demonstrates how coordinated policy adoption and infrastructure expansion can improve preventive care delivery and lower disease burden in high-prevalence regions. AIDS Transmission dynamics Health policy Climate and environment Treatment Guideline https://globalinfectiousdisease.com/research/articles/10-3201-eid0705-017507-d2f0f0fd/ https://globalinfectiousdisease.com/research/articles/10-3201-eid0705-017507-d2f0f0fd/ Mon, 01 Oct 2001 00:00:00 GMT The findings highlight potential roles for drought, cattle carriage of E. coli O157, and heavy rainfall in facilitating water contamination and disease emergence in this region. Surveillance Outbreak investigation Climate and environment Journal article