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  <title>GIDS Research Radar · Leishmaniasis</title>
  <link>https://globalinfectiousdisease.com/research/</link>
  <description>Published infectious-disease literature filtered to Leishmaniasis.</description>
  <language>en</language>
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  <lastBuildDate>Wed, 09 Sep 2026 07:02:01 GMT</lastBuildDate>
  <item>
    <title>Bi-directional highways and super-seeder tissues underpin parasite dissemination in experimental Leishmania donovani infection</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-77072-4-f26addaa/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>Clarifying these internal migration patterns may help explain recurring infections and therapeutic resistance, offering conceptual guidance for managing disease propagation.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>Treatment</category>
    <category>Ecological study</category>
  </item>
  <item>
    <title>Addressing the Gaps and Challenges of Autochthonous Mucocutaneous Leishmaniasis in Spain</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3390-tropicalmed11080235-dd86d1c5/</link>
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    <pubDate>Fri, 21 Aug 2026 00:00:00 GMT</pubDate>
    <description>Strengthening clinician education and integrating standardized protocols into official recommendations may decrease evaluation delays and treatment disparities.</description>
    <category>Leishmaniasis</category>
    <category>HIV infection</category>
    <category>Surveillance</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>From visceral to visible: A systematic review and meta-analysis of post-kala-azar dermal leishmaniasis incidence, risk factors, and treatment outcomes in Eastern Africa</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0014666-afa1362a/</link>
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    <pubDate>Tue, 18 Aug 2026 00:00:00 GMT</pubDate>
    <description>Consolidating regional outcome data helps identify modifiable therapeutic variables and highlights gaps in longitudinal tracking necessary for coordinated control initiatives.</description>
    <category>Kala-azar</category>
    <category>Leishmaniasis</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Cluster of imported cutaneous leishmaniasis due to Leishmania major among travellers returning from central Tunisia, France, October 2025 to May 2026</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2026-31-32-2600605-dac5d2bf/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2026-31-32-2600605-dac5d2bf/</guid>
    <pubDate>Thu, 13 Aug 2026 00:00:00 GMT</pubDate>
    <description>The reported cluster suggests potential changes in transmission intensity in central Tunisia and highlights the value of surveillance systems for detecting imported tropical infectious diseases in European clinical settings.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Travel medicine</category>
    <category>One Health</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Mental health, social determinants and One Health in skin neglected tropical diseases (NTDs): A scoping review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0014034-e5fafa04/</link>
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    <pubDate>Thu, 06 Aug 2026 00:00:00 GMT</pubDate>
    <description>The synthesis underscores the necessity of adopting comprehensive, multi-sectoral strategies and community-engaged methodologies to strengthen disease control initiatives and address systemic vulnerabilities affecting affected populations.</description>
    <category>Leishmaniasis</category>
    <category>One Health</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Subcutaneous immunization with kharon1-deficient leishmania infantum induces immunogenicity and protects hamsters against visceral leishmaniasis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128911-882d461e/</link>
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    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings provide experimental evidence that Likh1-/- may warrant further investigation as an immunoprophylactic approach for visceral leishmaniasis. The supplied evidence is limited to an animal model and does not establish effectiveness, safety, or feasibility in humans.</description>
    <category>Leishmaniasis</category>
    <category>Vaccination</category>
    <category>Vaccine effectiveness</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Recombinant vaccine plus anti-parasitic agent in an immunotherapeutic schedules induce partial regression of tegumentary leishmaniasis in a murine model</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128990-1f395e95/</link>
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    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>Current management options for tegumentary leishmaniasis face constraints regarding efficacy and adverse effects. This laboratory-based analysis highlights a potentially safer and more effective combinatorial approach that warrants subsequent developmental stages.</description>
    <category>Leishmaniasis</category>
    <category>Treatment</category>
    <category>Vaccination</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Risk factors for post-kala-azar dermal leishmaniasis (PKDL): Challenges in understanding pathophysiology</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013952-7b81c20d/</link>
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    <pubDate>Mon, 23 Feb 2026 00:00:00 GMT</pubDate>
    <description>The authors emphasize the need to integrate PKDL management within broader skin disease programs and to optimize VL treatment (e.g., multidrug regimens, immune modifiers) to potentially reduce PKDL incidence.</description>
    <category>Leishmaniasis</category>
    <category>Kala-azar</category>
    <category>Treatment</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-24-00581-4-857c8834/</link>
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    <pubDate>Sat, 01 Feb 2025 00:00:00 GMT</pubDate>
    <description>The abstract frames rhodesiense human African trypanosomiasis as a neglected tropical disease that is generally fatal if untreated. It states that the updated recommendations may matter for health-care professionals and policy makers.</description>
    <category>African trypanosomiasis</category>
    <category>Leishmaniasis</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Intensely clustered outbreak of visceral leishmaniasis (kala-azar) in a setting of seasonal migration in a village of Bihar, India</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-019-4719-3-d6b26cdd/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-019-4719-3-d6b26cdd/</guid>
    <pubDate>Mon, 06 Jan 2020 00:00:00 GMT</pubDate>
    <description>The outbreak demonstrates vulnerability in low-endemic areas and highlights gaps in case-finding, treatment delays, incomplete vector control coverage, and the role of social and economic determinants in kala-azar transmission. The findings underscore the need for a routine outbreak response framework within the elimination programme.</description>
    <category>Leishmaniasis</category>
    <category>Kala-azar</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Treatment</category>
    <category>Outbreak investigation</category>
  </item>
  <item>
    <title>Ecological niche modelling for predicting the risk of cutaneous leishmaniasis in the Neotropical moist forest biome</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0007629-fcb5f64e/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0007629-fcb5f64e/</guid>
    <pubDate>Wed, 14 Aug 2019 00:00:00 GMT</pubDate>
    <description>The risk maps can inform public health authorities about geographic areas where human modification of the environment elevates cutaneous leishmaniasis transmission risk, supporting targeted surveillance and intervention strategies in the Neotropical moist forest biome.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>One Health</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0006082-a3918826/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0006082-a3918826/</guid>
    <pubDate>Thu, 11 Jan 2018 00:00:00 GMT</pubDate>
    <description>Canine visceral leishmaniasis is relevant as dogs serve as a reservoir for Leishmania infantum, a zoonotic pathogen. Effective diagnosis, treatment, and control in canine populations may reduce transmission risk to humans.</description>
    <category>Leishmaniasis</category>
    <category>Leptospirosis</category>
    <category>Diagnostics</category>
    <category>Transmission dynamics</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Elimination of visceral leishmaniasis on the Indian subcontinent</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-16-30140-2-e52ce8f2/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-16-30140-2-e52ce8f2/</guid>
    <pubDate>Thu, 01 Dec 2016 00:00:00 GMT</pubDate>
    <description>Visceral leishmaniasis causes high morbidity and mortality on the Indian subcontinent and is a serious public health problem. The article addresses elimination strategies for a regional initiative targeting this disease burden.</description>
    <category>Leishmaniasis</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0003575-303d476e/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0003575-303d476e/</guid>
    <pubDate>Thu, 16 Apr 2015 00:00:00 GMT</pubDate>
    <description>The article identifies urgent needs to expand surveillance activities and ensure mass drug administration for populations at risk for intestinal helminth infections, fluke infections, lymphatic filariasis, trachoma, and yaws, while referencing the ASEAN Network for Drugs, Diagnostics, Vaccines, and Traditional Medicines Innovation as a policy framework for developing new control tools.</description>
    <category>Malaria</category>
    <category>Dengue</category>
    <category>Leprosy</category>
    <category>Filariasis</category>
    <category>Leishmaniasis</category>
    <category>Japanese Encephalitis</category>
    <category>Leptospirosis</category>
    <category>Schistosomiasis</category>
    <category>Melioidosis</category>
    <category>Trachoma</category>
    <category>Enterovirus 71 infection</category>
    <category>Climate and environment</category>
    <category>Surveillance</category>
    <category>One Health</category>
    <category>Health policy</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Rapid diagnostic tests for non-malarial febrile illness in the tropics</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1111-1469-0691-12154-162e7859/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1111-1469-0691-12154-162e7859/</guid>
    <pubDate>Wed, 01 May 2013 00:00:00 GMT</pubDate>
    <description>The article is relevant to diagnostic planning for tropical fever management in settings with limited access to laboratory testing. It frames better rapid tests as important for improving evaluation of treatable severe infections after malaria is excluded.</description>
    <category>Leptospirosis</category>
    <category>Dengue</category>
    <category>Malaria</category>
    <category>Leishmaniasis</category>
    <category>African trypanosomiasis</category>
    <category>Brucellosis</category>
    <category>Diagnostics</category>
    <category>Climate and environment</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Infection Parameters in the Sand Fly Vector That Predict Transmission of Leishmania major</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001288-a157043f/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001288-a157043f/</guid>
    <pubDate>Tue, 23 Aug 2011 00:00:00 GMT</pubDate>
    <description>The findings provide experimental context for factors associated with Leishmania transmission by sand fly vectors and for how infection conditions may relate to disease severity after transmission.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>Climate and environment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Leishmaniasis emergence in Europe</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-2807-ese-15-10-19505-en-4b6e99a9/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-2807-ese-15-10-19505-en-4b6e99a9/</guid>
    <pubDate>Thu, 11 Mar 2010 00:00:00 GMT</pubDate>
    <description>Findings inform EU-level risk assessment of leishmaniasis introduction and spread, highlighting surveillance, travel-related dog movement, and climate/land-use change as actionable axes for prevention and preparedness.</description>
    <category>Leishmaniasis</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Climate and environment</category>
    <category>Travel medicine</category>
    <category>One Health</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Control of Visceral Leishmaniasis in Latin America—A Systematic Review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0000584-88890f15/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0000584-88890f15/</guid>
    <pubDate>Tue, 19 Jan 2010 00:00:00 GMT</pubDate>
    <description>The study addresses VL, a neglected tropical disease, and provides evidence relevant to public health decision-making regarding control versus elimination strategies in Latin America, a region where zoonotic transmission presents distinct challenges compared to anthroponotic transmission patterns seen in South Asia.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>One Health</category>
    <category>Systematic review</category>
  </item>
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