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  <title>GIDS Research Radar · Malaria</title>
  <link>https://globalinfectiousdisease.com/research/</link>
  <description>Published infectious-disease literature filtered to Malaria.</description>
  <language>en</language>
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  <lastBuildDate>Wed, 09 Sep 2026 07:02:01 GMT</lastBuildDate>
  <item>
    <title>Built for the village, breached in the city: redesigning malaria vector control for Anopheles stephensi and insecticide resistance</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fmala-2026-1916446-3748bf02/</link>
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    <pubDate>Mon, 07 Sep 2026 00:00:00 GMT</pubDate>
    <description>The piece argues that vector control requires fundamental redesign to address urban transmission and insecticide resistance. It reviews next-generation nets with dual active ingredients, urban larval source management, and surveillance needs, emphasizing that entomological and resistance surveillance capacity is threatened by donor financing contraction.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Outbreak investigation</category>
    <category>Transmission dynamics</category>
    <category>Commentary</category>
  </item>
  <item>
    <title>Multiple local PfDHFR I164L haplotype expansions drive Plasmodium falciparum antifolate resistance in Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-76826-4-43defbd3/</link>
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    <pubDate>Fri, 04 Sep 2026 00:00:00 GMT</pubDate>
    <description>The findings are relevant to malaria control because the studied mutations are associated with antifolate resistance, and the paper describes PfDHFR I164L as conferring higher pyrimethamine resistance. The results indicate that resistance-related patterns may vary across locations using sulfadoxine-pyrimethamine chemoprevention.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Co-occurrence of pfkelch13 and pfmdr1 variants in a recurrent Plasmodium falciparum infection following standard artemether-lumefantrine treatment</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-109078-b7216bb3/</link>
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    <pubDate>Tue, 01 Sep 2026 00:00:00 GMT</pubDate>
    <description>The co-occurrence of resistance-associated markers and treatment failure in one patient is presented as justification for ongoing genomic surveillance of antimalarial resistance.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Genomic epidemiology</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Artemisinin partial resistance at a crossroads: evidence for continental variation in Plasmodium falciparum clearance phenotypes</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00132-5-db535b09/</link>
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    <pubDate>Tue, 01 Sep 2026 00:00:00 GMT</pubDate>
    <description>Applying southeast Asia-derived clearance thresholds in Africa may obscure early signals of artemisinin partial resistance and delay policy responses, supporting the need for region-specific surveillance criteria.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Treatment</category>
    <category>Health policy</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Molecular identification and phylogenetic analysis of Anopheles mosquitoes from malaria endemic-areas of Limpopo Province, South Africa</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s41936-026-00636-9-6fc68508/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings indicate that molecular testing may complement morphological identification in mosquito vector monitoring in the reported Limpopo setting. The abstract states that using additional, more variable markers alongside morphology could improve species discrimination and support malaria-control programmes.</description>
    <category>Malaria</category>
    <category>Genomic epidemiology</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Genomic study</category>
  </item>
  <item>
    <title>Multi-platform evidence of GSDMD-dependent pyroptosis in malaria with a potential role for TLR7</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fimmu-2026-1862560-360b0a8c/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>The study addresses macrophage-associated inflammation in malaria and identifies TLR7-mediated regulation of pyroptosis as a potential area for further investigation.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Deep learning–assisted malaria microscopy with sensitivity-aware threshold optimization</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fmed-2026-1911275-ed1ec55d/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>The work addresses a clinically meaningful failure mode of malaria microscopy—missed parasitized erythrocytes—and proposes a sensitivity-aware thresholding strategy that could reduce false negatives in screening workflows.</description>
    <category>Malaria</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Biological Activity of Artemisia mexicana: Antimalarial, Immunomodulatory, and Antioxidant Effects in Experimental Malaria</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3390-ijms27177637-5a8e0ebc/</link>
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    <pubDate>Wed, 26 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings suggest that Artemisia mexicana may offer therapeutic potential by addressing multiple pathogenic mechanisms in malaria, including parasite burden, immune dysregulation, and oxidative stress. These effects could inform future phytotherapeutic approaches, though human efficacy and safety data are required.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Plasmodium thiamine pyrophosphokinase is essential for sporozoite formation and activation of an antiplasmodial thiamine analogue</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1073-pnas-2534594123-de3aff17/</link>
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    <pubDate>Tue, 25 Aug 2026 00:00:00 GMT</pubDate>
    <description>TPK plays a critical role in sporogony within the mosquito vector, supporting its potential as a transmission-blocking target for antimalarial intervention.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>The effect of mefloquine dose on outcome of uncomplicated falciparum malaria treated with artesunate-mefloquine: a WWARN systematic review and individual patient data meta-analysis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12936-026-05963-4-1502247a/</link>
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    <pubDate>Tue, 25 Aug 2026 00:00:00 GMT</pubDate>
    <description>The results indicate that while the regimen remains effective, age-specific tolerability issues may constrain dosing adjustments in young children.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Transmission dynamics</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Dynamic hinge-motion of PfRIPR revealed by malaria invasion inhibitory antibodies</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-77069-z-fbf6ba93/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-77069-z-fbf6ba93/</guid>
    <pubDate>Mon, 24 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings may inform the design of vaccine immunogens based on PfRIPR and improve understanding of structural changes involved in erythrocyte invasion. The abstract does not provide evidence about effects in populations, vaccine effectiveness, or public-health outcomes.</description>
    <category>Malaria</category>
    <category>Vaccination</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Land-Use and Bakin Birji Pond Dynamics in Relation to Climate Variability and Malaria Seasonality in Zinder Region, Niger</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-9734-cjast-2026-v45i94751-2a4b7947/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-9734-cjast-2026-v45i94751-2a4b7947/</guid>
    <pubDate>Mon, 24 Aug 2026 00:00:00 GMT</pubDate>
    <description>The article provides local context on hydro-landscape change, climate measures, and seasonal malaria counts in one Nigerien setting. It identifies a need for finer environmental monitoring and longer, population-standardised malaria time series to evaluate temporal and causal relationships.</description>
    <category>Malaria</category>
    <category>Climate and environment</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>FEBRILE ILLNESS, MALARIA TEST POSITIVITY, AND BREAKTHROUGH INFECTION AMONG CHILDREN UNDER FIVE DURING SEASONAL MALARIA CHEMOPREVENTION IN PLATEAU STATE, NIGERIA: A RETROSPECTIVE ANALYSIS OF ROUTINE HEALTH FACILITY DATA, 2024</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-66837-ijbri01-522-04-bc3d9133/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-66837-ijbri01-522-04-bc3d9133/</guid>
    <pubDate>Sat, 22 Aug 2026 00:00:00 GMT</pubDate>
    <description>Routine monitoring highlights persistent diagnostic confirmation rates alongside widespread intervention coverage, indicating a need for enhanced programmatic tracking and periodic efficacy assessments.</description>
    <category>Malaria</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Rethinking malaria seasonality: humidity-driven transmission shifts and emerging hotspots in Zambia (2009–2023)</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fitd-2026-1842716-6177046e/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3389-fitd-2026-1842716-6177046e/</guid>
    <pubDate>Fri, 21 Aug 2026 00:00:00 GMT</pubDate>
    <description>Shifting environmental drivers necessitate updated operational approaches that prioritize flexible resource allocation and incorporate environmental monitoring into routine disease management frameworks.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Retrospective study of association between Plasmodium falciparum malaria density and platelet count at Presbyterian Hospital, Agogo</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fmala-2026-1875477-ea879f32/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3389-fmala-2026-1875477-ea879f32/</guid>
    <pubDate>Fri, 21 Aug 2026 00:00:00 GMT</pubDate>
    <description>Routine hematology analyzers may provide a swift, objective mechanism to prioritize suspected cases and streamline patient flow in settings where conventional parasitological testing encounters operational barriers.</description>
    <category>Plasmodium falciparum malaria</category>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Challenges in managing ruptured ectopic pregnancy complicated by hemorrhagic shock in an Ebola treatment unit in DR Congo: first reported case</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fmed-2026-1848720-5309eb14/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3389-fmed-2026-1848720-5309eb14/</guid>
    <pubDate>Fri, 21 Aug 2026 00:00:00 GMT</pubDate>
    <description>The case indicates that obstetric emergencies can arise in Ebola treatment units and that limited diagnostic, surgical, anesthetic, and referral capacity may complicate timely care. The authors conclude that such units should have capacity to diagnose and manage obstetric complications in addition to providing Ebola-related care.</description>
    <category>Ebola</category>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Heterogeneity of use, access, and retention of insecticide-treated nets: Implications for subnational tailoring to maximise malaria control</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-7554-elife-108745-4-d5839f7f/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-7554-elife-108745-4-d5839f7f/</guid>
    <pubDate>Thu, 20 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings indicate that subnational variation in net use after access may be relevant when considering malaria-control deployment strategies. The abstract describes a framework for using routinely collected data to support subnational programme tailoring.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Extending the Duration of Artemether-Lumefantrine Treatment for Uncomplicated Plasmodium falciparum Malaria: Updated US Centers for Disease Control and Prevention Guidance Based on Review of Surveillance, Consultations, and Published Data</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciag456-d08fe121/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciag456-d08fe121/</guid>
    <pubDate>Wed, 19 Aug 2026 00:00:00 GMT</pubDate>
    <description>The article provides evidence relevant to treatment policy for uncomplicated Plasmodium falciparum malaria among travelers in the United States. Its findings were reported as informing updated CDC guidance, but this summary does not independently assess that guidance or connect the article with a live surveillance signal.</description>
    <category>Malaria</category>
    <category>Plasmodium falciparum malaria</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Travel medicine</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Hidden burden of malaria in pregnancy in hard-to-reach areas of Odisha, India: challenges to elimination and the case for integrating molecular surveillance</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fpubh-2026-1862569-615b5e80/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3389-fpubh-2026-1862569-615b5e80/</guid>
    <pubDate>Tue, 18 Aug 2026 00:00:00 GMT</pubDate>
    <description>Undetected parasitic carriage among expectant mothers complicates regional disease eradication initiatives. Integrating advanced diagnostic capabilities into routine antenatal monitoring could improve intervention targeting and support national health objectives.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Cross-sectional study</category>
  </item>
  <item>
    <title>Delayed diagnosis of Plasmodium vivax malaria and associated factors among Thai patients and patients from neighboring countries at the Hospital for Tropical Diseases, Bangkok, Thailand</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1007-s15010-026-02930-8-9d04ab14/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1007-s15010-026-02930-8-9d04ab14/</guid>
    <pubDate>Mon, 17 Aug 2026 00:00:00 GMT</pubDate>
    <description>Recognizing these temporal barriers supports the development of region-specific awareness campaigns and triage guidelines for fever management in areas experiencing reduced transmission.</description>
    <category>Plasmodium vivax malaria</category>
    <category>Malaria</category>
    <category>Diagnostics</category>
    <category>Travel medicine</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Africa’s Silent Humanitarian Crisis: Why Viral Hepatitis Must No Longer Be Ignored</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-rescon-vmag135-8768e99e/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-rescon-vmag135-8768e99e/</guid>
    <pubDate>Mon, 17 Aug 2026 00:00:00 GMT</pubDate>
    <description>The article positions viral hepatitis as an urgent public health priority warranting immediate action through expanded testing, diagnosis, treatment, birth-dose vaccination, and integration with Universal Health Coverage initiatives.</description>
    <category>Viral Hepatitis</category>
    <category>Malaria</category>
    <category>Chronic hepatitis B</category>
    <category>Tuberculosis</category>
    <category>Hepatitis B</category>
    <category>Hepatitis C</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Malaria Transmission Via Needle Stick Injury: A Case Report and Systematic Review of the Literature.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1097-inf-0000000000005376-213986b0/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1097-inf-0000000000005376-213986b0/</guid>
    <pubDate>Mon, 17 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings document rare but recognized occupational transmission risk for healthcare workers managing malaria patients, emphasizing the need for standard precautions and post-exposure protocols in clinical settings where malaria is encountered.</description>
    <category>Malaria</category>
    <category>Plasmodium falciparum malaria</category>
    <category>Transmission dynamics</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Field evaluation of SumiLarv™ 2MR larvicide for controlling the invasive malaria vector Anopheles stephensi in Ethiopia: a randomised controlled trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12936-026-06089-3-b8294aa6/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12936-026-06089-3-b8294aa6/</guid>
    <pubDate>Mon, 17 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings suggest SumiLarv 2MR may be a suitable larval source management tool against the invasive urban-tolerant vector An. stephensi, which complicates existing malaria control in Ethiopia.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Treatment</category>
    <category>Climate and environment</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Climate blind spots in malaria control: frontline perspectives on climate adaptation and malaria control in Zambia</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3389-fitd-2026-1842769-295ce969/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3389-fitd-2026-1842769-295ce969/</guid>
    <pubDate>Mon, 17 Aug 2026 00:00:00 GMT</pubDate>
    <description>Integrating environmental monitoring into routine disease management protocols could enhance operational resilience during overlapping health emergencies. Developing targeted training modules on ecological risk assessment may improve how local teams adjust interventions to shifting conditions.</description>
    <category>Malaria</category>
    <category>Cholera</category>
    <category>COVID-19</category>
    <category>Climate and environment</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Health policy</category>
    <category>Cross-sectional study</category>
  </item>
  <item>
    <title>Experimental validation of a computationally designed mosquito midgut SGU protein-based epitope vaccine against malaria.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-dci-2026-105712-321d565d/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-dci-2026-105712-321d565d/</guid>
    <pubDate>Sat, 15 Aug 2026 00:00:00 GMT</pubDate>
    <description>The study is relevant to malaria prevention research because it explores a vaccine concept aimed at mosquito-parasite biology rather than treatment. It is an early-stage candidate described as needing further evaluation before any practical interpretation.</description>
    <category>Malaria</category>
    <category>Vaccination</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Generational selection, transcriptomics and functional characterization reveal the impact of environmental pollutants on the evolution of insecticide resistance in malaria vectors.</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ibmb-2026-104661-eb168492/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-ibmb-2026-104661-eb168492/</guid>
    <pubDate>Sat, 15 Aug 2026 00:00:00 GMT</pubDate>
    <description>Relevant to malaria control because it addresses insecticide resistance in malaria vectors and suggests environmental pollutants may be part of the resistance context.</description>
    <category>Malaria</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Severe Dengue and Dengue–Malaria Coinfection: A Case Series from a Referral Hospital in Montería, Colombia</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-3390-clinpract16080150-85e3307d/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-3390-clinpract16080150-85e3307d/</guid>
    <pubDate>Sat, 15 Aug 2026 00:00:00 GMT</pubDate>
    <description>Concurrent illness presentation complicates clinical assessment in tropical zones, suggesting that healthcare systems require enhanced diagnostic triage and continuous patient observation strategies.</description>
    <category>Dengue</category>
    <category>Malaria</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Phytochemical synergy in artemisia annua herbal tea against malaria: a systematic review of its efficacy and safety in the context of emerging Pfkelch13 resistance</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s40249-026-01486-x-ddb7856c/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s40249-026-01486-x-ddb7856c/</guid>
    <pubDate>Thu, 13 Aug 2026 00:00:00 GMT</pubDate>
    <description>The pronounced difference between rapid initial clearance and prolonged parasitological failure positions the botanical infusion as a supplementary measure rather than a definitive monotherapy in endemic regions.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Treatment</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Evaluation of the effectiveness of artemether–lumefantrine and artesunate–pyronaridine each combined with single low-dose primaquine in adults with Plasmodium falciparum infection in Ethiopia: a phase 2/3, observer-masked, randomised, parallel-group trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101344-b6e9fecd/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101344-b6e9fecd/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The data substantiate the sustained implementation of artemether-lumefantrine paired with primaquine while positioning the alternative pyronaridine-artesunate regimen as a reliable secondary option for areas confronting evolving drug resistance and diagnostic reliability concerns.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Diagnostics</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Longitudinal evidence of differential pertussis antibody durability following natural infection among vaccinated children living in contrasting malaria transmission settings in coastal Kenya</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128837-65ea5faf/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128837-65ea5faf/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>Persistent malaria transmission may erode long-term humoral immunity to pertussis following natural infection, with potential implications for pertussis control strategies and booster vaccination scheduling in malaria-endemic regions.</description>
    <category>Malaria</category>
    <category>Pertussis</category>
    <category>Vaccination</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Vaccine effectiveness</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Evaluation of immunogenicity and efficacy of a Plasmodium vivax nanoparticle vaccine in mice</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128857-f9db4a24/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128857-f9db4a24/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The adaptable architecture of this delivery mechanism supports future development of combined immunizations targeting multiple vivax malaria components, aligning with broader disease control objectives.</description>
    <category>Malaria</category>
    <category>Plasmodium vivax malaria</category>
    <category>Vaccination</category>
    <category>Vaccine effectiveness</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Impact of antigen and carrier substitution on the molecular weight and immunogenicity of the Pfs230D1–CRM197 malaria transmission-blocking vaccine</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128913-bbe2d1cc/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128913-bbe2d1cc/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings provide preclinical formulation and manufacturing context for development of a Pfs230D1-CRM197 malaria transmission-blocking vaccine. The supplied evidence does not report human immunogenicity, transmission reduction, clinical effectiveness, or population-level impact.</description>
    <category>Malaria</category>
    <category>Vaccination</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Prioritizing the introduction of new vaccine in Tanzania (2026–2030): a multi-criteria decision analysis by the Tanzania immunization technical advisory group</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128985-3837733d/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2026-128985-3837733d/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The documented scoring mechanism enables resource-limited jurisdictions to conduct systematic, transparent evaluations when expanding routine immunization programs.</description>
    <category>Hepatitis B</category>
    <category>Malaria</category>
    <category>Typhoid fever</category>
    <category>Mumps</category>
    <category>Rubella</category>
    <category>Measles</category>
    <category>Vaccination</category>
    <category>Surveillance</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Duration and association with protection of NANP-repeat-specific and C-terminus-specific anti-circumsporozoite protein IgG responses following RTS,S/AS01E vaccination: an observational ancillary immunological study of a phase 3 clinical trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00081-2-4c45715c/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00081-2-4c45715c/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings could inform immunological evaluation of RTS,S/AS01E by identifying antibody durability and maintenance, rather than peak responses alone, as potentially relevant correlates of vaccine efficacy.</description>
    <category>Malaria</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>Vaccine effectiveness</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Azithromycin with or without cefixime for suspected or culture-confirmed uncomplicated typhoid fever in Nepal, Bangladesh, and Pakistan (ACT-South Asia): a double-blind, parallel-group, randomised, placebo-controlled, phase 4 trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00358-0-b88ea3a1/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00358-0-b88ea3a1/</guid>
    <pubDate>Sat, 01 Aug 2026 00:00:00 GMT</pubDate>
    <description>The findings support the WHO recommendation of oral azithromycin monotherapy for uncomplicated typhoid fever and provide no evidence to justify adding cefixime, which has important antimicrobial stewardship implications given concerns about dual-drug resistance emergence.</description>
    <category>Typhoid fever</category>
    <category>COVID-19</category>
    <category>Dengue</category>
    <category>Malaria</category>
    <category>Typhus</category>
    <category>Scrub Typhus</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Safety, pharmacokinetics, and antimalarial efficacy of single-dose cabamiquine–pyronaridine combination therapy for the treatment of adults and adolescents with acute uncomplicated Plasmodium falciparum malaria (CAPTURE 1): a prospective, multicentre, open-label, phase 2a study</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00233-1-eef5750a/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-26-00233-1-eef5750a/</guid>
    <pubDate>Wed, 01 Jul 2026 00:00:00 GMT</pubDate>
    <description>The formulation offers a potential therapeutic alternative as artemisinin resistance continues to challenge current standard treatments. Subsequent research will determine appropriate pediatric dosing and confirm durability through expanded clinical testing.</description>
    <category>Malaria</category>
    <category>Plasmodium falciparum malaria</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-74737-y-6f2038f6/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-74737-y-6f2038f6/</guid>
    <pubDate>Fri, 26 Jun 2026 00:00:00 GMT</pubDate>
    <description>The work addresses an urgent regional challenge by quantifying how strategic antimalarial policy adjustments could preserve drug efficacy and reduce clinical failures over a six-year timeframe.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Transmission dynamics</category>
    <category>Health policy</category>
    <category>Mathematical modelling</category>
  </item>
  <item>
    <title>Modelling the impact of climate variability on malaria morbidity in the Tamale Metropolitan Area: a time series analysis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13796-4-ab352878/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-13796-4-ab352878/</guid>
    <pubDate>Sat, 13 Jun 2026 00:00:00 GMT</pubDate>
    <description>Integrating localized meteorological trends into forecasting tools may assist regional authorities in anticipating disease surges and optimizing preventive resource distribution.</description>
    <category>Malaria</category>
    <category>Climate and environment</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Signature of resistance gene evolution and pyrethroid resistance escalation in the major malaria vector Anopheles funestus across Kenyan malaria-endemic regions separated by the Rift Valley</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s40249-026-01458-1-3743c55a/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s40249-026-01458-1-3743c55a/</guid>
    <pubDate>Fri, 15 May 2026 00:00:00 GMT</pubDate>
    <description>Region-specific selection appears to generate distinct resistance profiles across Kenyan malaria-endemic zones, which has implications for malaria transmission and for tailoring insecticide resistance management strategies.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Antibody fine specificity correlates with protection from malaria for the RTS,S vaccine in young African children: A post hoc analysis of a phase IIb randomised controlled trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pmed-1004877-2633a3dc/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pmed-1004877-2633a3dc/</guid>
    <pubDate>Thu, 14 May 2026 00:00:00 GMT</pubDate>
    <description>Mapping these precise humoral targets may assist researchers in designing future immunizations with enhanced longevity and defensive capability.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Vaccination</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Molecular evidence of co-circulation of different dengue virus serotypes associated with malaria co-infection among febrile children in Libreville, Gabon</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-108497-993c2f2d/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-108497-993c2f2d/</guid>
    <pubDate>Fri, 01 May 2026 00:00:00 GMT</pubDate>
    <description>The authors highlight the need to strengthen differential diagnostic approaches and surveillance strategies for acute febrile illnesses in urban Gabon, given overlapping clinical presentations and co-endemicity of dengue and malaria.</description>
    <category>Dengue</category>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Diagnostics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Efficacy of ProC6C-AlOH/Matrix-M against Plasmodium falciparum infection and mosquito transmission: a phase 2, randomised, controlled human malaria infection study</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00664-4-e94d02c8/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00664-4-e94d02c8/</guid>
    <pubDate>Fri, 01 May 2026 00:00:00 GMT</pubDate>
    <description>This represents the first anti-PfCSP subunit vaccine demonstrating over 50% efficacy against CHMI at 12 weeks post-vaccination in a malaria-endemic setting. The findings support advancement to phase 2 efficacy trials against naturally acquired malaria and transmission in the target pediatric population.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Estimating the burden of imported malaria in the Asia Pacific region: a systematic review and meta-analysis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-jtm-taag022-c1c409f9/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-jtm-taag022-c1c409f9/</guid>
    <pubDate>Fri, 03 Apr 2026 00:00:00 GMT</pubDate>
    <description>Imported malaria represents a major barrier to achieving and sustaining malaria elimination in the Asia Pacific region, highlighting the need for strengthened cross-border coordination and tailored interventions.</description>
    <category>Malaria</category>
    <category>Surveillance</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Safety and efficacy of the monoclonal antibody L9LS for malaria prevention in children exposed to perennial malaria transmission in Kenya: a randomised, double-blind, placebo-controlled, phase 2 trial</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-26-00258-8-ecbd943f/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-s0140-6736-26-00258-8-ecbd943f/</guid>
    <pubDate>Wed, 01 Apr 2026 00:00:00 GMT</pubDate>
    <description>These outcomes indicate that targeted immunoprophylaxis may serve as a supplementary preventive measure for youth in endemic zones, though current dosing regimens require optimization for maximum impact.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Transmission dynamics</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Host macrophages/monocytes promote malaria transmission by modulating mosquito microbiota via SR-A-mediated phagocytosis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-70966-3-e19a0ddd/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-70966-3-e19a0ddd/</guid>
    <pubDate>Wed, 25 Mar 2026 00:00:00 GMT</pubDate>
    <description>The work points to a candidate intervention strategy—using anti-SR-A antibodies alongside anti-Pfs25 monoclonal antibodies—to strengthen transmission-blocking approaches against malaria.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Artesunate–pyronaridine–atovaquone–proguanil and artesunate–fosmidomycin–clindamycin compared with standard artesunate–pyronaridine for the treatment of uncomplicated malaria (MultiMal): a randomised, controlled, clinical, phase 2 trial in Gabon and Ghana</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101245-4f0f82f3/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101245-4f0f82f3/</guid>
    <pubDate>Sun, 01 Mar 2026 00:00:00 GMT</pubDate>
    <description>The authors position APAP and AFC as candidate multidrug combinations intended to address emerging artemisinin-reduced susceptibility in sub-Saharan Africa, warranting further clinical development.</description>
    <category>Malaria</category>
    <category>Treatment</category>
    <category>Antimicrobial resistance</category>
    <category>Randomised controlled trial</category>
  </item>
  <item>
    <title>Evaluating paratransgenesis using engineered symbiotic bacteria for Plasmodium inhibition in mosquito vectors: A systematic review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013654-8fa0324a/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013654-8fa0324a/</guid>
    <pubDate>Thu, 12 Feb 2026 00:00:00 GMT</pubDate>
    <description>The findings suggest paratransgenesis could complement existing malaria control approaches, particularly as insecticide and antimalarial drug resistance continue to emerge. The approach targets parasite transmission at the mosquito vector stage.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Systematic review</category>
  </item>
  <item>
    <title>Four-year monitoring of the malaria vector Anopheles funestus in central-west Cameroon reveals an escalation of pyrethroid resistance combined with high malaria transmission</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-12708-w-e9441f08/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-026-12708-w-e9441f08/</guid>
    <pubDate>Wed, 28 Jan 2026 00:00:00 GMT</pubDate>
    <description>The combination of high Plasmodium infection rates, co-circulation of three malaria parasite species, and intense pyrethroid resistance poses a serious threat to malaria control in the region. The findings support prioritizing deployment of PBO-based nets and organophosphate-based indoor residual spraying, along with continuous surveillance to guide intervention strategies toward malaria elimination.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Surveillance</category>
    <category>Treatment</category>
    <category>Journal article</category>
  </item>
  <item>
    <title>Analytical and data-driven fractional-order malaria transmission model with vector and non-vector pathways</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-12219-0-827c63f8/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-12219-0-827c63f8/</guid>
    <pubDate>Tue, 09 Dec 2025 00:00:00 GMT</pubDate>
    <description>The model framework supports reproducibility through MATLAB implementation and offers potential application to malaria forecasting and control strategy development.</description>
    <category>Malaria</category>
    <category>Transmission dynamics</category>
    <category>Outbreak investigation</category>
    <category>Mathematical modelling</category>
  </item>
  <item>
    <title>Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2025-107940-1b1b3b68/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2025-107940-1b1b3b68/</guid>
    <pubDate>Mon, 01 Sep 2025 00:00:00 GMT</pubDate>
    <description>The authors describe the reported outbreak as indicating a need for greater investment in dengue research, vaccine development, vector control, and therapeutic strategies. They also recommend adding dengue virus infection to the WHO Research and Development Priority Disease list.</description>
    <category>Dengue</category>
    <category>Malaria</category>
    <category>Outbreak investigation</category>
    <category>Surveillance</category>
    <category>Vaccination</category>
    <category>Treatment</category>
    <category>Climate and environment</category>
    <category>Journal article</category>
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