https://globalinfectiousdisease.com/research/ Published infectious-disease literature filtered to Smallpox. en Wed, 09 Sep 2026 07:02:01 GMT https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-76580-7-00f2b79e/ https://globalinfectiousdisease.com/research/articles/10-1038-s41467-026-76580-7-00f2b79e/ Tue, 11 Aug 2026 00:00:00 GMT The article is relevant to monkeypox outbreak investigation and transmission dynamics because it addresses phenotypic differences in a virus lineage associated with the 2022 global epidemic. Its focus on zoonotic MPXV and orthopoxvirus transmission gives it One Health relevance. Monkeypox Smallpox Outbreak investigation Transmission dynamics One Health Journal article https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-109047-cef9afc2/ https://globalinfectiousdisease.com/research/articles/10-1016-j-ijid-2026-109047-cef9afc2/ Sat, 01 Aug 2026 00:00:00 GMT Monkeypox infection and smallpox vaccination may provide cross-protection against orthopoxviruses. Early IgA detection could support mpox diagnosis in asymptomatic high-risk individuals, and complement-dependent neutralization assays may improve cross-immunity assessment. Smallpox Monkeypox Vaccination Vaccine effectiveness Journal article https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00545-6-9f0c6065/ https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00545-6-9f0c6065/ Sun, 01 Feb 2026 00:00:00 GMT The observed differences in immune durability between natural infection and vaccination highlight potential considerations for maintaining population-level protection against circulating orthopoxviruses. Smallpox Monkeypox Vaccination Cohort study https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00018-0-0c50fdeb/ https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-25-00018-0-0c50fdeb/ Tue, 01 Jul 2025 00:00:00 GMT The article provides Germany-specific observational evidence on MVA-BN safety and estimated effectiveness in the population studied during the 2022-2023 mpox period. Its findings may inform editorial context about vaccination evidence, including the reported difference in estimated effectiveness by HIV status, but they do not establish causality or confirm a current surveillance pattern. Smallpox Monkeypox Vaccination Vaccine effectiveness Outbreak investigation Transmission dynamics Cohort study https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7422a3-e39ea2c9/ https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7422a3-e39ea2c9/ Thu, 19 Jun 2025 00:00:00 GMT The recommendations provide outbreak-specific vaccination guidance amid ongoing mpox transmission and substantial morbidity and mortality. Future need for the outbreak recommendation will be reassessed as the outbreak evolves. Smallpox Monkeypox Vaccination Outbreak investigation Transmission dynamics Journal article https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013148-060ab7b4/ https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0013148-060ab7b4/ Thu, 12 Jun 2025 00:00:00 GMT The authors argue Mpox has the potential to disrupt health systems and undermine progress toward the 2030 sustainable development goals, calling for financial and human resource support from countries both within and outside Africa. Monkeypox Smallpox Surveillance Outbreak investigation Transmission dynamics Vaccination Climate and environment One Health Journal article https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2024-29-38-2400575-f7a0beb2/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2024-29-38-2400575-f7a0beb2/ Thu, 19 Sep 2024 00:00:00 GMT The findings indicate that antibody responses to MVA-BN vaccination may not persist beyond one year, highlighting the need for ongoing surveillance to assess the public health implications of declining antibody levels for mpox outbreak preparedness. Smallpox Monkeypox Vaccination Outbreak investigation Surveillance Journal article https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-23-00492-9-83571f46/ https://globalinfectiousdisease.com/research/articles/10-1016-s1473-3099-23-00492-9-83571f46/ Mon, 01 Jan 2024 00:00:00 GMT Cataloging symptom profiles in previously immune populations aids researchers in understanding how prior exposure modifies disease presentation within affected networks. Monkeypox Smallpox Vaccination Outbreak investigation Journal article https://globalinfectiousdisease.com/research/articles/10-1056-nejmoa2215201-466804dd/ https://globalinfectiousdisease.com/research/articles/10-1056-nejmoa2215201-466804dd/ Thu, 29 Jun 2023 00:00:00 GMT The findings support the usefulness of JYNNEOS vaccination against mpox disease and suggest greater protection with completion of the two-dose series, relevant to U.S. outbreak control among at-risk adults. Monkeypox Smallpox HIV infection AIDS Vaccination Vaccine effectiveness Outbreak investigation Case-control study https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2023-28-12-2200772-971f344b/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2023-28-12-2200772-971f344b/ Thu, 23 Mar 2023 00:00:00 GMT The findings characterize a high-incidence mpox outbreak in a specific population and provide quantitative estimates of vaccine protection, contributing evidence relevant to vaccination strategy and risk communication for at-risk communities. Smallpox Monkeypox Vaccination Travel medicine Outbreak investigation Transmission dynamics Vaccine effectiveness Journal article https://globalinfectiousdisease.com/research/articles/10-1038-s41591-022-02090-w-3f5be3bf/ https://globalinfectiousdisease.com/research/articles/10-1038-s41591-022-02090-w-3f5be3bf/ Tue, 18 Oct 2022 00:00:00 GMT These observations address knowledge gaps surrounding authorized MVA-BN deployment during a recently declared international health emergency by quantifying early immune responses. Influenza Monkeypox Smallpox Vaccination Outbreak investigation Vaccine effectiveness Journal article https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0010141-156f368b/ https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0010141-156f368b/ Fri, 11 Feb 2022 00:00:00 GMT The review highlights the global relevance of monkeypox given its spread beyond endemic African settings and suggests that enhanced surveillance is needed to monitor its evolving epidemiology. Monkeypox Smallpox Travel medicine Surveillance Transmission dynamics Vaccination One Health Systematic review https://globalinfectiousdisease.com/research/articles/10-2807-ese-15-35-19651-en-b9605ba4/ https://globalinfectiousdisease.com/research/articles/10-2807-ese-15-35-19651-en-b9605ba4/ Thu, 02 Sep 2010 00:00:00 GMT The findings provide a model-based comparison of vaccination strategies for controlling a simulated smallpox outbreak and may inform analysis of vaccination policy in comparable modeled settings. The abstract does not establish effectiveness in actual outbreaks or surveillance data. COVID-19 Smallpox Influenza Vaccination Outbreak investigation Surveillance Transmission dynamics Health policy Journal article https://globalinfectiousdisease.com/research/articles/10-3201-eid0911-030369-f24a0548/ https://globalinfectiousdisease.com/research/articles/10-3201-eid0911-030369-f24a0548/ Sat, 01 Nov 2003 00:00:00 GMT The findings provide quantitative decision thresholds for smallpox vaccination policy, balancing rare but serious vaccine complications against bioterrorism or outbreak risk in the post-eradication era. Smallpox SARS COVID-19 Vaccination Transmission dynamics Vaccine effectiveness Journal article https://globalinfectiousdisease.com/research/articles/10-1056-nejm198011273032204-4b7984fd/ https://globalinfectiousdisease.com/research/articles/10-1056-nejm198011273032204-4b7984fd/ Thu, 27 Nov 1980 00:00:00 GMT A key post-certification account of how eradication status was confirmed and guarded. Smallpox Surveillance Vaccination Health policy Journal article