https://globalinfectiousdisease.com/research/ Published infectious-disease literature filtered to Syphilis. en Wed, 09 Sep 2026 07:02:01 GMT https://globalinfectiousdisease.com/research/articles/10-3389-fmed-2026-1899418-175b22f4/ https://globalinfectiousdisease.com/research/articles/10-3389-fmed-2026-1899418-175b22f4/ Wed, 26 Aug 2026 00:00:00 GMT The report underscores the rising incidence of syphilis and the need to recognize atypical clinicopathological presentations, supporting routine syphilis screening for accurate diagnosis and timely treatment. Syphilis Treatment Journal article https://globalinfectiousdisease.com/research/articles/10-1097-qco-0000000000001234-117d9b89/ https://globalinfectiousdisease.com/research/articles/10-1097-qco-0000000000001234-117d9b89/ Mon, 24 Aug 2026 00:00:00 GMT The review is framed around the U.S. resurgence of maternal and congenital syphilis, noting associated neonatal morbidity and mortality and calling for more practical, safe management approaches. Syphilis Congenital syphilis Syphilis in pregnancy Treatment Health policy Guideline https://globalinfectiousdisease.com/research/articles/10-3390-ijerph23081090-faea2511/ https://globalinfectiousdisease.com/research/articles/10-3390-ijerph23081090-faea2511/ Fri, 21 Aug 2026 00:00:00 GMT The findings point to gaps in provider knowledge, attitudes, practice, and adherence related to a program aimed at reducing mother-to-child transmission of HIV, syphilis, and hepatitis B, underscoring the need for targeted improvement efforts in maternal services. Hepatitis B Syphilis AIDS Transmission dynamics Cross-sectional study https://globalinfectiousdisease.com/research/articles/10-7717-peerj-21632-561aeb09/ https://globalinfectiousdisease.com/research/articles/10-7717-peerj-21632-561aeb09/ Tue, 18 Aug 2026 00:00:00 GMT The elevated detection rates indicate that routine maternal testing may help identify vulnerable pregnancies and potentially reduce pathogen transfer to offspring. Rubella Toxoplasmosis Syphilis Transmission dynamics Systematic review https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaf504-aa5bc359/ https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaf504-aa5bc359/ Wed, 04 Feb 2026 00:00:00 GMT The unprecedented surge in congenital syphilis cases underscores the need for improved prenatal screening, timely maternal treatment, and enhanced diagnostic capacity to prevent serious long-term sequelae in affected infants. Syphilis Congenital syphilis Transmission dynamics Treatment Diagnostics Journal article https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaf651-2c805f85/ https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaf651-2c805f85/ Fri, 19 Dec 2025 00:00:00 GMT Rapid point-of-care testing enables same-day treatment for individuals in nontraditional settings, addressing barriers to testing and treatment among key populations. The intervention was associated with significant declines in new syphilis positivity rates in a high-income setting experiencing resurgence of heterosexual syphilis transmission. Syphilis Congenital syphilis Treatment Outbreak investigation Journal article https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-12263-w-cfa51897/ https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-12263-w-cfa51897/ Mon, 08 Dec 2025 00:00:00 GMT Accelerated diagnostic workflows may streamline clinical decision-making and support antimicrobial stewardship by clarifying infection status prior to therapeutic decisions. Syphilis Infectious syphilis Treatment Diagnostics Journal article https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-11601-2-156ec51e/ https://globalinfectiousdisease.com/research/articles/10-1186-s12879-025-11601-2-156ec51e/ Mon, 29 Sep 2025 00:00:00 GMT The findings highlight the critical public health challenge posed by emerging antibiotic resistance in gonococcal infections and emphasize the need for antimicrobial stewardship, enhanced contact tracing, and comprehensive monitoring systems. Syphilis Treatment Antimicrobial resistance Outbreak investigation Systematic review https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7312a2-110d0a68/ https://globalinfectiousdisease.com/research/articles/10-15585-mmwr-mm7312a2-110d0a68/ Thu, 28 Mar 2024 00:00:00 GMT The substantial increase in ceftriaxone resistance threatens gonorrhea treatment effectiveness in China, where gonorrhea ranked as the fourth most common notifiable infectious disease in 2022 with 96,313 reported cases. Effective diagnosis, treatment, and partner management are essential to prevent transmission of resistant strains. Gonorrhea Syphilis Tuberculosis Viral Hepatitis Treatment Antimicrobial resistance Surveillance Transmission dynamics Journal article https://globalinfectiousdisease.com/research/articles/10-1186-s12879-024-09019-3-5bf76d5e/ https://globalinfectiousdisease.com/research/articles/10-1186-s12879-024-09019-3-5bf76d5e/ Thu, 29 Feb 2024 00:00:00 GMT Dual point-of-care tests could serve as a cost-effective, patient-friendly, and provider-friendly alternative to conventional testing in clinical and field settings, particularly in resource-limited environments where validated screening tools may help reduce HIV and syphilis incidence. Syphilis AIDS Diagnostics Treatment Meta-analysis https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciac056-ae5175ee/ https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciac056-ae5175ee/ Tue, 25 Jan 2022 00:00:00 GMT The frequent detection of Treponema pallidum DNA in multiple anatomic sites even without visible lesions may help explain high syphilis transmission rates and suggests opportunities for earlier presymptomatic diagnosis. Detection in oropharyngeal and ano-rectal sites highlights potential transmission routes beyond classic presentations. Syphilis Treatment Transmission dynamics Diagnostics Journal article https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaa349-46b9a3b9/ https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaa349-46b9a3b9/ Wed, 24 Jun 2020 00:00:00 GMT Clarifying the operational characteristics of validated screening tools assists health authorities in maintaining consistent diagnostic pathways and optimizing laboratory resource distribution for endemic disease control. Syphilis Diagnostics Treatment Systematic review https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2018-23-19-17-00381-2b7b94a8/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2018-23-19-17-00381-2b7b94a8/ Thu, 10 May 2018 00:00:00 GMT The UK achieved WHO elimination status in 2016, with high vaccination uptake and rubella immunity in the population. Most pregnancy infections since 2003 occurred in unvaccinated women and were acquired abroad, suggesting that verification of complete immunization at every healthcare contact remains important. Rubella Congenital rubella syndrome Syphilis Measles Surveillance Vaccination Treatment Journal article https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2017-22-42-17-00673-7817fed7/ https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2017-22-42-17-00673-7817fed7/ Thu, 19 Oct 2017 00:00:00 GMT The outbreak occurred after the United Kingdom had achieved interrupted endemic measles transmission for 36 months in 2016, illustrating the ongoing risk of imported measles cases. Measles Syphilis Outbreak investigation Vaccination Treatment Transmission dynamics Journal article https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw348-52e3095b/ https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw348-52e3095b/ Mon, 23 May 2016 00:00:00 GMT Rapid diagnostic tests could expand screening access for syphilis, which causes substantial stillbirth and neonatal mortality through vertical transmission, and for yaws, with nearly 100,000 endemic cases reported annually. Syphilis Diagnostics Treatment Transmission dynamics Meta-analysis