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  <title>GIDS Research Radar · Meta-analysis</title>
  <link>https://globalinfectiousdisease.com/research/</link>
  <description>Published infectious-disease literature filtered to Meta-analysis.</description>
  <language>en</language>
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  <lastBuildDate>Wed, 09 Sep 2026 07:02:01 GMT</lastBuildDate>
  <item>
    <title>Extending the Duration of Artemether-Lumefantrine Treatment for Uncomplicated Plasmodium falciparum Malaria: Updated US Centers for Disease Control and Prevention Guidance Based on Review of Surveillance, Consultations, and Published Data</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciag456-d08fe121/</link>
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    <pubDate>Wed, 19 Aug 2026 00:00:00 GMT</pubDate>
    <description>The article provides evidence relevant to treatment policy for uncomplicated Plasmodium falciparum malaria among travelers in the United States. Its findings were reported as informing updated CDC guidance, but this summary does not independently assess that guidance or connect the article with a live surveillance signal.</description>
    <category>Malaria</category>
    <category>Plasmodium falciparum malaria</category>
    <category>Treatment</category>
    <category>Surveillance</category>
    <category>Travel medicine</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Evaluating the risk of dapsone hypersensitivity syndrome in Nepalese Leprosy Patients via HLA-B* 13:01 screening using real-time PCR and comparative meta-analysis of international data</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0014568-d8a82d06/</link>
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    <pubDate>Thu, 13 Aug 2026 00:00:00 GMT</pubDate>
    <description>Routine pre-therapy genetic assessment might lower the burden of severe medication-related complications in endemic regions with limited laboratory infrastructure.</description>
    <category>Leprosy</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Single-gene transcripts for subclinical tuberculosis: an individual participant data meta-analysis</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101186-823ba6a7/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-lanmic-2025-101186-823ba6a7/</guid>
    <pubDate>Sat, 01 Nov 2025 00:00:00 GMT</pubDate>
    <description>Simplified single-gene biomarkers could offer a more scalable option for identifying candidates for tuberculosis preventive therapy, especially where IGRAs perform poorly, and may complement IGRAs in low-burden programmes.</description>
    <category>Tuberculosis</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Transmission pathways and risk factors for sporadic salmonellosis and campylobacteriosis: a source attribution meta-analysis of European case-control studies</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1017-s095026882510023x-db41138e/</link>
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    <pubDate>Tue, 01 Jul 2025 00:00:00 GMT</pubDate>
    <description>Findings reinforce poultry as a primary source for both pathogens and highlight the broader role of zoonotic transmission pathways, including environmental and occupational exposures, in European sporadic cases.</description>
    <category>Campylobacteriosis</category>
    <category>Salmonellosis</category>
    <category>Transmission dynamics</category>
    <category>Climate and environment</category>
    <category>Travel medicine</category>
    <category>One Health</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Global meta-analysis of short-term associations between ambient temperature and pathogen-specific respiratory infections, 2004 to 2023</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2025-30-11-2400375-afcc4cc6/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-2807-1560-7917-es-2025-30-11-2400375-afcc4cc6/</guid>
    <pubDate>Thu, 20 Mar 2025 00:00:00 GMT</pubDate>
    <description>The abstract frames pathogen-specific temperature sensitivity as relevant to planning for warmer climatic conditions. It states that public health decision-makers should develop pathogen adaptation strategies.</description>
    <category>MERS</category>
    <category>SARS</category>
    <category>COVID-19</category>
    <category>Influenza</category>
    <category>Climate and environment</category>
    <category>Health policy</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Independent clinic-based evaluation of dual POCTs for screening for HIV and syphilis in men who have sex with men in Italy, Malta, Peru, and the United Kingdom</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-024-09019-3-5bf76d5e/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-024-09019-3-5bf76d5e/</guid>
    <pubDate>Thu, 29 Feb 2024 00:00:00 GMT</pubDate>
    <description>Dual point-of-care tests could serve as a cost-effective, patient-friendly, and provider-friendly alternative to conventional testing in clinical and field settings, particularly in resource-limited environments where validated screening tools may help reduce HIV and syphilis incidence.</description>
    <category>Syphilis</category>
    <category>AIDS</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Rapid review and meta-analysis of serial intervals for SARS-CoV-2 Delta and Omicron variants</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-023-08407-5-fafc6047/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-023-08407-5-fafc6047/</guid>
    <pubDate>Mon, 26 Jun 2023 00:00:00 GMT</pubDate>
    <description>Shorter serial intervals indicate more rapid transmission between case generations, consistent with faster growth dynamics observed for Delta and Omicron compared to earlier variants. Understanding serial interval is important for determining reproduction numbers and secondary attack rates, which inform control measures.</description>
    <category>COVID-19</category>
    <category>SARS</category>
    <category>Transmission dynamics</category>
    <category>Vaccination</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Mapping the human genetic architecture of COVID-19</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1038-s41586-021-03767-x-7efdf208/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1038-s41586-021-03767-x-7efdf208/</guid>
    <pubDate>Thu, 08 Jul 2021 00:00:00 GMT</pubDate>
    <description>The findings highlight potentially actionable biological mechanisms and modifiable risk factors relevant to COVID-19, and the study is presented as a model for international data-sharing collaboration in future pandemics.</description>
    <category>SARS</category>
    <category>COVID-19</category>
    <category>Treatment</category>
    <category>Outbreak investigation</category>
    <category>Climate and environment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Two-dose varicella vaccine effectiveness in China: a meta-analysis and evidence quality assessment</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1186-s12879-021-06217-1-ce4edd97/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1186-s12879-021-06217-1-ce4edd97/</guid>
    <pubDate>Wed, 09 Jun 2021 00:00:00 GMT</pubDate>
    <description>The findings suggest that two-dose varicella vaccination is highly effective in preventing varicella and is recommended for countries seeking further control of the disease.</description>
    <category>Varicella</category>
    <category>Vaccination</category>
    <category>Outbreak investigation</category>
    <category>Vaccine effectiveness</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Aminoglycosides and Capreomycin in the Treatment of Multidrug-resistant Tuberculosis: Individual Patient Data Meta-analysis of 12 030 Patients From 25 Countries, 2009–2016</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaa621-ac7175ec/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciaa621-ac7175ec/</guid>
    <pubDate>Fri, 30 Oct 2020 00:00:00 GMT</pubDate>
    <description>The findings suggest that streptomycin and amikacin should be preferred over kanamycin or capreomycin when drug susceptibility testing supports their use, potentially improving treatment success rates for MDR-TB patients worldwide.</description>
    <category>Tuberculosis</category>
    <category>Multidrug-resistant tuberculosis</category>
    <category>Treatment</category>
    <category>Antimicrobial resistance</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Global Childhood Deaths From Pertussis: A Historical Review</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw529-4078fd52/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw529-4078fd52/</guid>
    <pubDate>Sat, 12 Nov 2016 00:00:00 GMT</pubDate>
    <description>Mortality reduction is a key WHO vaccine impact indicator. The findings highlight gaps in long-term enumeration of residual infant deaths and maternal seroprevalence data, particularly in low- and middle-income countries considering maternal pertussis vaccination. More precise immune correlates of infant protection against death would strengthen program planning.</description>
    <category>Pertussis</category>
    <category>Diphtheria</category>
    <category>Tetanus</category>
    <category>Vaccination</category>
    <category>Surveillance</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Metaanalysis of the Performance of a Combined Treponemal and Nontreponemal Rapid Diagnostic Test for Syphilis and Yaws</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw348-52e3095b/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1093-cid-ciw348-52e3095b/</guid>
    <pubDate>Mon, 23 May 2016 00:00:00 GMT</pubDate>
    <description>Rapid diagnostic tests could expand screening access for syphilis, which causes substantial stillbirth and neonatal mortality through vertical transmission, and for yaws, with nearly 100,000 endemic cases reported annually.</description>
    <category>Syphilis</category>
    <category>Diagnostics</category>
    <category>Treatment</category>
    <category>Transmission dynamics</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Cochrane re-arranged: Support for policies to vaccinate elderly people against influenza</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2013-09-063-bb30bea6/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1016-j-vaccine-2013-09-063-bb30bea6/</guid>
    <pubDate>Sun, 01 Dec 2013 00:00:00 GMT</pubDate>
    <description>The authors interpret the re-arranged evidence as supporting policies to vaccinate elderly people against influenza and as providing substantial evidence that vaccination can reduce infection and related disease and death in this group.</description>
    <category>Influenza</category>
    <category>Health policy</category>
    <category>Vaccination</category>
    <category>Vaccine effectiveness</category>
    <category>Vaccine safety</category>
    <category>Climate and environment</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pmed-1001300-1126bd94/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pmed-1001300-1126bd94/</guid>
    <pubDate>Tue, 28 Aug 2012 00:00:00 GMT</pubDate>
    <description>The findings provide evidence context on treatment regimens and outcomes in multidrug-resistant tuberculosis, including associations involving drug selection and the number of likely effective drugs. The supplied article does not establish causal effects or indicate the current prevalence, distribution, or trend of multidrug-resistant tuberculosis.</description>
    <category>Tuberculosis</category>
    <category>Treatment</category>
    <category>Antimicrobial resistance</category>
    <category>Meta-analysis</category>
  </item>
  <item>
    <title>Infection Parameters in the Sand Fly Vector That Predict Transmission of Leishmania major</title>
    <link>https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001288-a157043f/</link>
    <guid isPermaLink="true">https://globalinfectiousdisease.com/research/articles/10-1371-journal-pntd-0001288-a157043f/</guid>
    <pubDate>Tue, 23 Aug 2011 00:00:00 GMT</pubDate>
    <description>The findings provide experimental context for factors associated with Leishmania transmission by sand fly vectors and for how infection conditions may relate to disease severity after transmission.</description>
    <category>Leishmaniasis</category>
    <category>Transmission dynamics</category>
    <category>Climate and environment</category>
    <category>Meta-analysis</category>
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