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Peer reviewedOpen accessTuberculosis

First isolation of Mycobacterium tuberculosis from suspected cases of bovine tuberculosis in rural abattoirs in Chad.

Tropical animal health and production·

Lamireou D, Ngandolo BN, Koné P, Tadio S, Diguimbaye C, Alambédji R, Zinsstag J, Bonfoh B

DOI
10.1007/s11250-026-04949-3
PMID
41917553
PMCID
PMC13038451
OpenAlex
W7147398267
Study type
Cross-sectional study
Publisher
Publisher unavailable
Article type
journal-article
Integrity
current

Why this research matters now

The findings document both M. bovis and M. tuberculosis in cattle presented for human consumption in Chad, underscoring the multi-species nature of agents producing suspected tuberculous lesions in abattoir settings and the relevance of zoonotic and reverse-zoonotic considerations at the human–livestock interface.

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Structured evidence summary

Research question

The study aimed to assess the multi-species composition of causative agents of tuberculosis infection in domestic ruminants intended for human consumption.

Study design

A cross-sectional abattoir-based study conducted in 2012 across 7 abattoirs in southern Chad, using bacteriology and molecular typing on collected lesion samples.

Population and setting

Suspected tuberculous lesions were sampled from 327 cattle carcasses in southern Chad abattoirs, dominated by Arabic (234) and Fulani (91) breeds, with most animals aged 3–12 years; 112 carcasses were male and 215 female.

Main findings

Mycobacterium bovis was isolated from 42 suspected bovine carcasses, while a single M. tuberculosis strain was recovered from a 6-year-old female Fulani. Non-tuberculous mycobacteria accounted for about 3% (10) of suspected carcasses. Sex had a statistically significant association with infection, with females roughly twice as likely as males (p=0.04, OR=1.7).

Public-health relevance

The findings document both M. bovis and M. tuberculosis in cattle presented for human consumption in Chad, underscoring the multi-species nature of agents producing suspected tuberculous lesions in abattoir settings and the relevance of zoonotic and reverse-zoonotic considerations at the human–livestock interface.

Important limitations

This summary is limited to the supplied single-article abstract/metadata and requires the original paper for decision-grade interpretation. Explicit limitations (e.g., sampling frame, regional scope, or diagnostic methods) are not detailed in the abstract beyond describing a cross-sectional design restricted to 7 southern Chad abattoirs in 2012.

GIDS interpretation

Within the GIDS discoverability context, the article is indexed under tuberculosis, One Health, and transmission dynamics topics, with Chad as the geographic focus. It may aid editorial reviewers seeking literature on multi-host tuberculosis agents at the livestock–human interface, but no connection to a live surveillance signal is made.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 6 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicstudied instudied population settinguses study design