A systematic review of evidence that enteroviruses may be zoonotic
Emerging Microbes & Infections·
- DOI
- 10.1038/s41426-018-0159-1
- PMID
- 30258048
- PMCID
- PMC6158190
- OpenAlex
- W2894101213
- Study type
- Systematic review
- Publisher
- Informa UK Limited
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The review highlights cross-species transmission as a plausible pathway for enterovirus emergence and underscores the value of periodic surveillance at the human-animal interface, consistent with a One Health framing.
Structured evidence summary
Research question
The review examines whether enteroviruses may be transmitted between humans and other mammalian species, addressing both zooanthroponosis and anthropozoonosis directions.
Study design
Systematic review of English and Chinese literature published between 2007 and 2017. Of 2,704 articles screened, 16 were included in the final synthesis.
Population and setting
Not applicable: the unit of analysis is the published literature rather than a defined human or animal population. Enteroviruses are noted to infect millions of humans annually, primarily infants and children.
Main findings
The included studies yielded considerable molecular evidence of zooanthroponosis transmission, particularly involving non-human primates. Instances of anthropozoonosis transmission were more limited, but the authors interpret the data as supporting biological plausibility of cross-species transmission and the need for periodic surveillance at the human-animal interface.
Public-health relevance
The review highlights cross-species transmission as a plausible pathway for enterovirus emergence and underscores the value of periodic surveillance at the human-animal interface, consistent with a One Health framing.
Important limitations
Source-scope limitation: the included studies were restricted to English and Chinese literature published between 2007 and 2017, and only 16 of 2,704 screened articles met inclusion criteria, which constrains the evidence base. This summary is limited to the supplied single-article abstract and metadata and should be supplemented with the original paper for decision-grade interpretation.
GIDS interpretation
Indexer-relevant context only: this systematic review consolidates molecular evidence on enterovirus cross-species transmission, most prominently among non-human primates, and aligns with One Health, transmission dynamics, and surveillance descriptors. No connection is made to any live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 7 auditable classifier relationships to diseases, places, topics, and study design.