The entity is defined as a source-reported CPE surveillance category that is non-additive and separate from wide CPO and CRE surveillance concepts [1]. CPE are Enterobacteriaceae producing Ambler class A (KPC), class B metallo-β-lactamases such as NDM, or class D OXA-48-like carbapenemases [2].
Disease overview
BacterialCarbapenemase-producing Enterobacteriaceae surveillance
产碳青霉烯酶肠杆菌科细菌监测
Follow this disease Compare countries Evidence-backed information EN 1/6 applicable sections · ZH 1/6 applicable sections Updated Oct 23, 2026
Carbapenemase-producing Enterobacteriaceae (CPE) surveillance denotes a source-reported classification scope for CPE that is kept distinct from broader carbapenemase-producing organisms and carbapenem-resistant Enterobacteriaceae constructs [1]. CPE are recognized as an escalating global health threat, with rising incidence driven by both clonal spread and plasmid-mediated transmission [2].
Read the full clinical and epidemiological profile 2
- 1 GlobalID Disease Ontology. GlobalID ontology concept D244: Carbapenemase-producing Enterobacteriaceae surveillance [Internet]. cited 23 Oct 2026. Available from: https://github.com/xmusphlkg/globalID2/blob/development/configs/disease_ontology.json
- 2 van Duin D et al. The global epidemiology of carbapenemase-producing Enterobacteriaceae. Virulence. 2017 May 19. PMID: 27593176. doi: 10.1080/21505594.2016.1222343. PubMed: https://pubmed.ncbi.nlm.nih.gov/27593176/
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