The term denotes surveillance activities focused on source-identified penicillin-non-susceptible or resistant Streptococcus pneumoniae, which may capture infection or carriage states [1]. This classification is explicitly not equivalent to invasive pneumococcal disease and supplies only a non-additive scope without clinical or epidemiological assertions [1].
Disease overview
BacterialPenicillin-non-susceptible/resistant pneumococcal surveillance
青霉素敏感性降低或耐药肺炎球菌监测
Follow this disease Compare countries Evidence-backed information EN 3/6 applicable sections · ZH 2/6 applicable sections Updated Oct 23, 2026
Penicillin-non-susceptible or resistant pneumococcal surveillance is a source-defined classification scope concerning Streptococcus pneumoniae isolates with reduced or absent penicillin susceptibility, potentially encompassing both infection and carriage [1]. It is distinguished from invasive pneumococcal disease and reflects a non-additive ontological category rather than a clinical entity [1].
Read the full clinical and epidemiological profile 4
English source text only
The underlying pneumococcal disease spectrum includes pneumonia, bacterial meningitis, sepsis, otitis media, and sinusitis. Clinical manifestations are linked to pneumococcal virulence factors, while the surveillance definition itself is based on penicillin susceptibility status rather than a particular clinical syndrome. [2]
Pneumococci are reported as frequent colonizers of the upper respiratory tract, with higher amounts described in environments where people spend substantial time in close proximity, including day-care centers and military barracks. Penicillin resistance has increased over time and is especially prevalent in areas with high antibiotic use; resistant strains may also show resistance to several other antibacterial classes. [2]
- 1 GlobalID Disease Ontology. GlobalID ontology concept D239: Penicillin-non-susceptible/resistant pneumococcal surveillance [Internet]. cited 23 Oct 2026. Available from: https://github.com/xmusphlkg/globalID2/blob/development/configs/disease_ontology.json
- 2 Wikipedia contributors. Pneumococcal infection - Wikipedia [Internet]. Wikipedia. cited 11 Aug 2026. Available from: https://en.wikipedia.org/wiki/Pneumococcal_infection
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