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Peer reviewedOpen accessCOVID-19SARS

Digital measurement of SARS-CoV-2 transmission risk from 7 million contacts

Nature·

Luca Ferretti, Chris Wymant, James Petrie, Daphne Tsallis, Michelle Kendall, Alice Ledda, Francesco Di Lauro, Adam Fowler, Andrea Di Francia, Jasmina Panovska-Griffiths, Lucie Abeler-Dörner, Marcos Charalambides, Mark Briers, Christophe Fraser

DOI
10.1038/s41586-023-06952-2
PMID
38122820
PMCID
PMC10830410
OpenAlex
W4389991868
Study type
Guideline
Publisher
Springer Science and Business Media LLC
Article type
journal-article
Integrity
current

Why this research matters now

The findings challenge the widely used 2-meter, 15-minute guideline for contact tracing and demonstrate that privacy-preserving digital contact-tracing data can rapidly inform public health measures during emerging pathogen outbreaks.

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Structured evidence summary

Research question

The study sought to determine how proximity measurements and exposure duration recorded by a contact-tracing app relate to the actual probability of SARS-CoV-2 transmission.

Study design

This was an observational analysis of 7 million contacts notified through the National Health Service COVID-19 app in England and Wales, using empirical metrics and statistical modeling to link app-computed risk scores to transmission probability.

Population and setting

The population consisted of individuals using the NHS COVID-19 app in England and Wales who were either confirmed cases or notified contacts during the pandemic.

Main findings

Transmission probability increased linearly with exposure duration at approximately 1.1% per hour and continued rising over several days. Longer exposures at greater distances carried similar risk to shorter exposures at closer distances. Most exposures were brief (median 0.7 hours), but transmissions typically arose from prolonged contact lasting between 1 hour and several days (median 6 hours). Households represented about 6% of contacts but accounted for 40% of transmissions.

Public-health relevance

The findings challenge the widely used 2-meter, 15-minute guideline for contact tracing and demonstrate that privacy-preserving digital contact-tracing data can rapidly inform public health measures during emerging pathogen outbreaks.

Important limitations

This summary relies on the supplied single-article abstract and metadata. Full interpretation of study limitations, including potential biases in app adoption, measurement accuracy, and test reporting, requires review of the original paper.

GIDS interpretation

This article is discoverable through disease classifiers for SARS and COVID-19, and topic classifiers for health policy, outbreak investigation, and transmission dynamics. It provides evidence on how digital proximity data can quantify transmission risk, relevant to outbreak response infrastructure rather than to any active surveillance signal.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 10 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseabout diseaseaddresses topicaddresses topicaddresses topichas pathogen typeinforms policy domainstudied population settingstudies pathogenuses study design