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Public-health topic

Outbreak investigation

Published Research Radar records connected to the Outbreak investigation topic through the auditable classification pipeline.

Published evidence
400
Diseases
72
Countries
96
Topics
14

Evidence stream

Published literature

400

30 of 400 publications shown

Field Investigation of the Bundibugyo Ebola Virus Disease (BDBV) Outbreak in Ituri Province, Democratic Republic of the Congo: Challenges, Strategies, and Priority Actions for Outbreak Control—An Outbreak Investigation Review

Muambangu Jean Paul Milambo, Christian Ngandu

Infectious Disease Reports

Type
Outbreak investigation
Scope
Democratic Republic of the Congo, Uganda

Why it matters nowThe abstract frames the outbreak as a major Ebola control challenge in a conflict-affected and socially complex setting. It identifies surveillance, contact tracing, laboratory capacity, IPC, clinical care, risk communication, misinformation management, and community trust as priority areas for outbreak response and preparedness.

Built for the village, breached in the city: redesigning malaria vector control for Anopheles stephensi and insecticide resistance

Shyamkumar Sriram

Frontiers in Malaria

Type
Commentary
Scope
Not classified

Why it matters nowThe piece argues that vector control requires fundamental redesign to address urban transmission and insecticide resistance. It reviews next-generation nets with dual active ingredients, urban larval source management, and surveillance needs, emphasizing that entomological and resistance surveillance capacity is threatened by donor financing contraction.

Implementing an intra outbreak ring vaccination clinical trial for Sudan Ebola virus disease within four days of outbreak notification in Uganda.

Muttamba W, Bosa HK, Wayengera M +14 more

Emerging microbes & infections

Type
Journal article
Scope
Sudan, Uganda, Democratic Republic of the Congo

Why it matters nowThe four-day turnaround provides a replicable blueprint for rapid medical countermeasure evaluation during future outbreaks in settings with heightened Ebola Virus Disease threat. The approach demonstrates that prepositioned protocols, established infrastructure, and trained personnel can dramatically compress trial activation timelines.

Regional signals preceding the 2026 Bundibugyo virus disease outbreak

Nahid Bhadelia, Isaac Gikandi, Britta Lassmann

International Journal of Infectious Diseases

Type
Journal article
Scope
Democratic Republic of the Congo, Burundi, South Sudan

Why it matters nowFindings point to potential deficiencies in protocols for managing cases that test negative for standard pathogens.

The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities

Yi Zhang, Junkai Ren, Xuejun Ma +1 more

Infectious Medicine

Type
Journal article
Scope
Democratic Republic of the Congo, Uganda

Why it matters nowThe document underscores urgent requirements for novel prophylactic and therapeutic development while demonstrating how transnational coordination mechanisms can address complex outbreak environments marked by infrastructure deficits and social friction.

H5N1 Clade 2.3.4.4b Infections in Domestic Cats During an Avian Influenza Outbreak in Italy: Implications for One Health Surveillance.

D'Annunzio G, Moreno A, Tosi G +27 more

Influenza and other respiratory viruses

Type
Journal article
Scope
Italy

Why it matters nowThe findings are positioned as relevant to surveillance for cross-species transmission and potential spillover risk, given the documented mammalian-adaptation mutation and expanding host range of clade 2.3.4.4b.

Clustering and Source Association of Clinical and Nonclinical Listeria monocytogenes Isolates, New York, USA, 2000-2021<sup>1</sup>.

Samut H, Mendez-Vallellanes DV, Hoyt H +10 more

Emerging infectious diseases

Type
Genomic study
Scope
United States

Why it matters nowThe authors suggest that whole-genome sequencing may strengthen outbreak investigation and source attribution for L. monocytogenes and that produce-associated transmission may reflect distinct pathways.

Mixing versus matching booster vaccines: A longitudinal humoral immune kinetics against Omicron in a Malaysian cohort

Ashwathy Varadarajan Thundakattil, Rekha Prabhu, Girish Prabhu +12 more

International Journal of Infectious Diseases

Type
Cohort study
Scope
Malaysia

Why it matters nowThe findings offer immunogenicity evidence relevant to booster vaccination strategy decisions during Omicron-era outbreaks, with particular relevance to settings where inactivated virus priming is used.

Beyond Exposure: A Comprehensive Vision for Healthcare Worker Protection.

Del Parco F

La Clinica terapeutica

Type
Journal article
Scope
Not classified

Why it matters nowThe article supports a shift from narrow infection prevention strategies to integrated approaches that address both biological and psychosocial occupational hazards, potentially improving healthcare workforce sustainability and system resilience.

Using high frequency GPS data to assess wintering goose proximity to commercial poultry facilities on the Delmarva peninsula for avian influenza risk management and surveillance.

Hardy MJ, Williams CK, Ladman BS +8 more

PloS one

Type
Journal article
Scope
Canada, United States

Why it matters nowThe findings describe a possible way to prioritize biosecurity or surveillance resources around poultry facilities using observed wintering-waterfowl presence. This is an evidence-context signal from the supplied article and does not establish that the ranking method is validated for current surveillance or outbreak prediction.

Autochthonous chikungunya virus outbreak in Verona province, Italy, 2025

Concetta Castilletti, Leonardo Ancillotti, Antonio Mori +30 more

Journal of Travel Medicine

Type
Genomic study
Scope
Italy, Réunion

Why it matters nowThe report illustrates how coordinated monitoring networks can quickly characterize emerging arboviral activity in non-endemic areas, offering insights into optimal diagnostic windows and the importance of continuous pathogen tracking.

Recombinant Influenza Vaccine and Influenza Outbreaks in US Nursing Homes: Results from a Pragmatic Cluster-Randomized Clinical Trial

Kevin W McConeghy, H Edward Davidson, Lisa Han +4 more

Open Forum Infectious Diseases

Type
Journal article
Scope
United States

Why it matters nowThe results suggest that deploying this specific immunization strategy may help curb institutional transmission episodes during years with active seasonal pathogen circulation, thereby potentially reducing operational disruptions within elderly care infrastructure.

Estimation of serial intervals and time-varying reproduction numbers across SARS-CoV-2 variants in childcare clusters: symptom onset vs. reporting dates

Hee Kyoung Kim, Jin Lee, Young-Man Kim +2 more

BMC Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters nowThe findings suggest that relying on reporting dates in surveillance systems may underestimate real-time transmission intensity and distort epidemic risk assessment in childcare settings, which are high-risk environments for respiratory virus transmission.

Monitoring Cholera Transmission in Zambia Using the Cholera Elimination Scorecard

Caroline C. Chisenga, Lilian Lamba, Charlie C. Luchen +10 more

The American Journal of Tropical Medicine and Hygiene

Type
Journal article
Scope
Zambia

Why it matters nowPublic health authorities managing elimination campaigns may utilize this straightforward assessment method alongside established multisectoral planning protocols.

PCR-Based Detection of Priority Bacterial Biological Threat Agents: Advances in Diagnosis of Anthrax, Tularemia and Brucellosis

A. P. Gerilovych, N. O. Shevchenko, H. Ye. Anan’ina +4 more

One Health Journal

Type
Journal article
Scope
Not classified

Why it matters nowThe article presents molecular detection of these high-consequence pathogens as relevant to preparedness, outbreak investigation, environmental and wildlife monitoring, laboratory readiness, and coordinated One Health activities. The supplied abstract describes potential operational relevance but does not provide outcome data demonstrating effects on public health practice.

Phylogenetic and phylogeographic analysis of equine influenza in Colombia.

Gonzalez-Obando J, Carrillo M, Diaz FJ +9 more

Equine veterinary journal

Type
Genomic study
Scope
Colombia, United States

Why it matters nowThe genetic proximity to foreign viral strains highlights cross-border animal trade as a potential introduction pathway, emphasizing the need for continuous genomic monitoring to track strain evolution and guide control measures.

Understanding moral trade-offs in pandemic response: A discrete choice experiment on avian influenza policies.

Smeele NVR, Waltz CNM, Schreijer AJM +1 more

The European journal of health economics : HEPAC : health economics in prevention and care

Type
Journal article
Scope
Not classified

Why it matters nowThe findings suggest that public acceptance of preparedness policies may depend on perceived moral legitimacy as well as expected effectiveness and financial cost. The abstract reports that incorporating these preference differences into economic evaluation could inform consideration of societal acceptability.

Measles outbreak risk in Afghanistan: provincial immunity gaps and epidemic potential following immunisation system disruption.

Ranjan R, Anwari P, Colson A +1 more

Vaccine

Type
Journal article
Scope
Afghanistan

Why it matters nowThe findings suggest that routine one-dose MCV delivery alone is insufficient to reach the measles population-immunity threshold under the model's central assumptions, and that sustained two-dose routine immunisation, high-reach SIAs, and restored immunisation-system capacity may be required.

From SARS to COVID‐19: Crisis Governance and Institutional Learning in Taiwan

Ching‐Cheng Lin

Journal of Contingencies and Crisis Management

Type
Journal article
Scope
Taiwan, China

Why it matters nowThe article offers an analytical account of Taiwan's pandemic preparedness trajectory and identifies conditions under which lessons from one public health crisis transfer (or fail to transfer) to a subsequent one, informing comparative crisis management scholarship.

High mpox mortality in people living with HIV and immune suppression: Lessons from Sierra Leone for integrated outbreak preparedness and response

Rosamund Felicity Lewis, Chikwe Andreas Ihekweazu

Journal of Interventional Epidemiology and Public Health

Type
Cohort study
Scope
Sierra Leone

Why it matters nowThe piece argues for integrated HIV/STI and mpox prevention and care, pre-exposure vaccination of at-risk people, continued investment in surveillance and data systems, and pre-approved emergency research protocols as part of outbreak preparedness, with a long-term aim beyond acute response.

A rapid detection of Nipah virus nucleocapsid antigen in inactivated viral cultures.

Choi G, Kim J, Lee H +15 more

Emerging microbes & infections

Type
Journal article
Scope
Not classified

Why it matters nowThe paper is relevant to outbreak preparedness because it describes a rapid antigen test intended for Nipah virus detection in settings where nucleic-acid testing may be difficult to use. The abstract frames the assay as potentially useful for point-of-care diagnosis in resource-limited contexts.

Peer reviewedOpen accessChikungunyaOutbreak investigation
DOI 10.1093/ofid/ofag534 ↗

Evidence of chikungunya virus reinfection in two patients with lupus during the 2024–2025 outbreak on Reunion Island

Anissa Desmoulin, Dimitri Kornblum, Marie-Christine Jaffar-Bandjee +6 more

Open Forum Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters nowThe observations suggest that assumptions of durable chikungunya immunity may not hold universally, which could inform risk communication and clinical management for vulnerable groups during outbreaks.

Negotiating security and resilience: planning conundrums for avian influenza control in Great Britain’s poultry systems

Mathew Hennessey, Pablo Alarcon, Paniz Hosseini +2 more

Environmental Research: Food Systems

Type
Journal article
Scope
United Kingdom

Why it matters nowThe research highlights critical gaps in agricultural risk management that could facilitate pathogen persistence and impact broader food security frameworks.

Genomic and epidemiological evidence linking a pre-season dengue case to local overwintering transmission in Guangdong, China

Liling Lin, Man Liu, Jianqian Chen +13 more

PLOS Neglected Tropical Diseases

Type
Genomic study
Scope
China

Why it matters nowThe observation indicates that viral persistence across off-season periods may occur in warming subtropical zones, highlighting the necessity for continuous mosquito monitoring programs.

Peer reviewedOpen accessPoliomyelitisAcute flaccid paralysisSurveillanceOutbreak investigationTransmission dynamics
DOI 10.1186/s13690-026-02047-2 ↗

Progress toward poliomyelitis eradication — January 2023–December 2024

Hailey Whitmire, M. Zubair Wadood, Ina G. Storm +7 more

Archives of Public Health

Type
Journal article
Scope
Afghanistan, Pakistan

Why it matters nowThe findings highlight the continued risk posed by persistent WPV1 transmission in endemic areas and the geographic spread of cVDPVs, informing the need for improved campaign quality, sustained surveillance, expanded nOPV2 use where cVDPV2 transmission persists, and strategic resource allocation under declining global health funding.

Melioidosis in South Asia: Scientific Advances, Regional Challenges and One Health Perspectives—An Integrated Research Synthesis from the 4th South Asian Melioidosis Congress

Chiranjay Mukhopadhyay, Chimanjita Phukan, Saurav Jyoti Patgiri +3 more

Wellcome Open Research

Type
Journal article
Scope
Australia, India

Why it matters nowThe compilation frames melioidosis as an escalating yet frequently ignored infectious threat that demands improved monitoring frameworks, uniform testing standards, and interdisciplinary coordination to decrease adverse health outcomes.

Influence of Heat Wave and Precipitation on Chikungunya Transmission

Wei Yan, Jianping Huang, Shujuan Hu +2 more

Geophysical Research Letters

Type
Journal article
Scope
Not classified

Why it matters nowThe findings indicate that increasingly frequent extreme weather events may heighten the risk of chikungunya outbreaks, suggesting that public health preparedness should account for weather-related transmission drivers.

Mapping the Surveillance Data Infrastructure in the U.S. for SARS-CoV-2, Influenza, and Respiratory Syncytial Virus

Akshay Deverakonda, Emily E. Ricotta, John T. Kubale

Current Epidemiology Reports

Type
Journal article
Scope
United States

Why it matters nowClarifying the scope and availability of these monitoring frameworks may streamline epidemiological investigations and support more effective emergency management strategies.

Peer reviewedOpen accessFoodborne disease outbreakOutbreak investigation
DOI 10.3389/fpubh.2026.1883871 ↗

Explainable machine learning framework for foodborne disease outbreak prediction in Eastern Province, Saudi Arabia: case study

Naof Faiz Saleem Al-Ansary, Mahmood Berekaa, Raghad Alhotheyfa +3 more

Frontiers in Public Health

Type
Journal article
Scope
Saudi Arabia

Why it matters nowThe authors frame the work as a proof-of-concept illustrating how predictive modeling, interpretability, and spatial risk mapping could be combined to support future foodborne outbreak surveillance in urbanizing settings.

Dynamics of global mpox epidemics, 1970–2025: a systematic review and meta-analysis of evolving transmissibility and intervention effects

Yin-Chien Lin, Tzai-Hung Wen, Wei-Liang Shih +3 more

BMJ Global Health

Type
Systematic review
Scope
Not classified

Why it matters nowMonitoring progressive changes in viral spread capabilities underscores the importance of timely, balanced resource distribution paired with localized educational initiatives to mitigate future transmission waves.