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Peer reviewedTularemia

Macular serpiginous chorioretinitis associated with Francisella tularensis: A case report.

Retinal cases & brief reports·

Friedl EM, Simmen S, Langenegger S, Gunzinger JM, Hasse B, Zweifel S, Barthelmes D, Al-Sheikh M

DOI
10.1097/icb.0000000000001977
PMID
42640705
PMCID
OpenAlex
Study type
Journal article
Publisher
Publisher unavailable
Article type
journal-article
Integrity
current

Why this research matters now

The report draws attention to tularemia as a rare zoonotic trigger of atypical, rapidly progressive chorioretinal inflammation, encouraging clinicians to consider zoonotic infections in such cases.

01

Structured evidence summary

Research question

To describe a rare presentation of bilateral macular serpiginous chorioretinitis linked to Francisella tularensis infection after rabbit exposure.

Study design

Observational single case report using multimodal retinal imaging together with systemic and serologic evaluation.

Population and setting

A single patient with bilateral rapidly progressive central visual loss and placoid macular lesions following rabbit exposure, evaluated in an ophthalmologic clinical setting.

Main findings

Serology confirmed Francisella tularensis infection, and doxycycline treatment produced regression of inflammation with residual outer retinal atrophy.

Public-health relevance

The report draws attention to tularemia as a rare zoonotic trigger of atypical, rapidly progressive chorioretinal inflammation, encouraging clinicians to consider zoonotic infections in such cases.

Important limitations

No explicit limitations are stated in the abstract. As an isolated case report, it cannot establish frequency, generalizability, or causal mechanisms. This summary is limited to the supplied single-article abstract and metadata and requires the original paper for decision-grade interpretation.

GIDS interpretation

Within the GIDS literature workflow, this single case report sits in the infectious/uveitis subdomain and contributes discoverable evidence on a rare zoonotic ocular manifestation; it does not, by itself, indicate or confirm any live surveillance signal for tularemia-related chorioretinitis.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 6 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicevaluates interventionstudied population settinguses study design