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Peer reviewedOpen accessTuberculosis

Operational performance of GeneXpert for tuberculosis diagnosis in West Java province, Indonesia: a public health evaluation.

BMC health services research·

Nijman G, Alifia A, Annisa SN, Shurianto L, de Boer IE, Puspitasari I, Indriani S, Alisjahbana B, van Crevel R, Hill PC, Lestari BW

DOI
10.1186/s12913-026-14658-0
PMID
42121171
PMCID
OpenAlex
W4409218748
Study type
Journal article
Publisher
Publisher unavailable
Article type
journal-article
Integrity
current

Why this research matters now

Addressing these operational gaps requires coordinated multi-agency strategies and practical adjustments to diagnostic rollout processes to sustain tuberculosis control efforts.

01

Structured evidence summary

Research question

The investigation assesses how effectively GeneXpert technology functions within routine tuberculosis testing workflows and identifies systemic barriers affecting its deployment.

Study design

Researchers performed a cross-sectional facility assessment supplemented by structured interviews with clinical and administrative personnel.

Population and setting

Data collection occurred across forty community health centers situated in West Java province, Indonesia, engaging nursing staff, laboratory technicians, and program administrators.

Main findings

Implementation outcomes demonstrated considerable variation, with notably low performance metrics regarding staff training completion, private sector sample referrals, rapid specimen transport, high testing volumes, minimal technical errors, uninterrupted reagent supplies, equipment reliability, and scheduled maintenance. Operational obstacles involved workforce shortages, remote locations, and inadequate digital networks, while effective stakeholder dialogue and preliminary deployment reviews supported better system adoption.

Public-health relevance

Addressing these operational gaps requires coordinated multi-agency strategies and practical adjustments to diagnostic rollout processes to sustain tuberculosis control efforts.

Important limitations

The analysis relies on a single-province cross-sectional assessment, which restricts broader geographic applicability and prevents longitudinal tracking of performance changes over time.

GIDS interpretation

This publication offers retrospective contextual information regarding diagnostic infrastructure capacity in a defined Indonesian jurisdiction, providing background reference rather than indicating current epidemiological shifts or active monitoring alerts.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 6 auditable classifier relationships to diseases, places, topics, and study design.

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