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Public-health topic

Diagnostics

Published Research Radar records connected to the Diagnostics topic through the auditable classification pipeline.

Published evidence
1011
Diseases
125
Countries
148
Topics
14

Evidence stream

Published literature

1011

30 of 1011 publications shown

Comparative Histopathology of Yellow Fever in New and Old World Non-Human Primates: Hepatic and Extrahepatic Lesions in Susceptible Species

D. Katterine Bonilla-Aldana, Jorge Luis Bonilla-Aldana, Ivan Camilo Sanchez-Rojas +3 more

Pathogens

Type
Journal article
Scope
Not classified

Why it matters now According to the abstract, comparative primate pathology can support early-warning surveillance of epizootics, inform human vaccination strategies, aid wildlife conservation, and strengthen One Health outbreak preparedness.

Peer reviewed Open access SyphilisCOVID-19 SurveillanceDiagnosticsTreatment
DOI 10.3389/fpubh.2026.1960182 ↗

Trends and projections of the syphilis burden in China: an analysis of GBD 2021 data and global comparison

Wei Li, Wei Wei, Wei-Feng Shen

Frontiers in Public Health

Type
Journal article
Scope
China

Why it matters now The authors identify prenatal syphilis screening and timely, evidence-based treatment as important for preventing congenital syphilis, and emphasize improved clinician recognition of late-stage syphilis complications. They also call for investigation of whether healthcare disruptions, surveillance artifacts, or reporting changes contributed to the recent mortality and DALY trends.

Measurement Error Correction and Multidimensional Aggregation in Epidemiological Surveillance Systems: Application to the Ebola Virus Disease Epidemic in the Democratic Republic of the Congo

Joseph Kasiama Ngi Onkor, Camile Likotelo Binene, Glad Lufimpu Mampuya

Asian Journal of Research in Computer Science

Type
Journal article
Scope
Democratic Republic of the Congo

Why it matters now The framework provides a formal design basis for surveillance decision-support systems that explicitly incorporate data quality, with demonstrated implications for incidence and reproduction-number estimates.

Absence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 (Pfhrp2/3) Gene Deletions in Rizal, Palawan, the Philippines

Jennifer S. Luchavez, Alison Paolo N. Bareng, Freya Spencer +6 more

The American Journal of Tropical Medicine and Hygiene

Type
Journal article
Scope
Philippines

Why it matters now The findings are relevant to malaria elimination in the Philippines: the authors suggest that molecular monitoring of pfhrp2 deletions in routine surveillance could improve assessment of RDT performance and support elimination strategies targeting 2030.

Seroepidemiology of human leptospirosis in subtropical Bhutan, 2024

Monu Tamang, Rie Takeuchi, Thinley Dorji +11 more

PLOS Neglected Tropical Diseases

Type
Cross-sectional study
Scope
Bhutan

Why it matters now The findings indicate substantial prior Leptospira exposure in the sampled communities and support prevention education, protective equipment during high-risk activities, expanded epidemiologic and surveillance capacity, and stronger hospital-based diagnostics.

Peer reviewed Open access HIV infectionLeishmaniasis Diagnostics
DOI 10.4269/ajtmh.26-0104 ↗

A Diagnostic Algorithm Based on Urine Antigen and Blood Polymerase Chain Reaction Testing for Visceral Leishmaniasis in HIV-Coinfected Patients in Northwest Ethiopia

Ermias Diro, Koert Ritmeijer, Saskia van Henten +6 more

The American Journal of Tropical Medicine and Hygiene

Type
Journal article
Scope
Ethiopia, United Kingdom

Why it matters now The supplied abstract states the sequential algorithm supports efficient resource use and reduces the need for invasive tissue aspiration procedures in this patient group.

Peer reviewed Open access COVID-19 Diagnostics
DOI 10.1093/ofid/ofag722 ↗

Higher Diagnostic Yield of Sputum Versus Oropharyngeal Swabs for Viral Pathogens in Hospitalized Non-COVID-19 Community-acquired Pneumonia

Pei Min Thong, Dorothy Hui Lin Ng, Sharlene Ho +87 more

Open Forum Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters now The results may inform specimen selection when viral testing is needed for community-acquired pneumonia management and infection-control decisions in hospitalized patients.

Peer reviewed Open access Filariasis TreatmentDiagnostics
DOI 10.4269/ajtmh.26-0392 ↗

Pulmonary Dirofilaria immitis Infection and Concurrent Pleural Lymphangiomatosis in a Young Woman from Costa Rica: A Diagnostic Challenge after 20 Years of Silence

Daniel Cascante-Serrano, Manuel Villalobos-Zúñiga, Daniela Salazar-Porras +4 more

The American Journal of Tropical Medicine and Hygiene

Type
Journal article
Scope
Costa Rica

Why it matters now The report characterizes human dirofilariasis as an underreported, vector-borne disease and emphasizes the diagnostic value of integrating clinical, molecular, and histopathological approaches in endemic settings.

Peer reviewed Open access Hepatitis CChronic hepatitis C Diagnostics
DOI 10.1186/s43066-026-00569-6 ↗

Circulating hypermethylated RASSF1A as a possible marker of hepatocellular carcinoma in chronic hepatitis C patients

Mona Hassona, Nevine F. Shafik, Eman Abdelsameea +5 more

Egyptian Liver Journal

Type
Journal article
Scope
Not classified

Why it matters now The findings suggest a possible non-invasive blood-based diagnostic approach for identifying HCC among patients with post-HCV cirrhosis, which could be relevant where minimizing invasive procedures is important. The abstract does not establish readiness for routine clinical use.

The role of animals in the epidemiology and pathogenesis of severe fever with thrombocytopenia syndrome (SFTS): a scoping review

Jian Li, Zhebin Hu, Hai Tong +12 more

Infectious Diseases of Poverty

Type
Journal article
Scope
China

Why it matters now Findings highlight the need for coordinated One Health actions—tick control, farm biosecurity, and public outreach—to reduce spillover and burden.

Tularemia: una zoonosis reemergente

Marta Hernández, José Antonio Oteo, José Mª Eiros

Medicina Clínica

Type
Genomic study
Scope
United States, Austria, Spain

Why it matters now High virulence, low infectious dose, and bioterrorism classification highlight the need for current clinical and diagnostic guidance to support preparedness.

Bayesian latent class analysis for evaluating diagnostic performance of three serological tests of bovine brucellosis in Pakistan

Muhammad Taimoor, Abdul Sammad Ali Khan Shirwany, Mian Muhammad Awais +4 more

Preventive Veterinary Medicine

Type
Cross-sectional study
Scope
Pakistan

Why it matters now Findings suggest that a single serological test is inadequate for bovine brucellosis screening in this setting and that parallel testing with SAT+iELISA is needed for field screening, with implications for zoonotic disease control in Pakistan.

PCR-enabled confirmatory reporting and the rise in reported pertussis among children aged ≤5 years in China: a four-province staggered difference-in-differences study

Hongwei Liu, Qian Zhang, Mingshuang Li +6 more

International Journal of Infectious Diseases

Type
Journal article
Scope
China

Why it matters now The work shows that revision of diagnostic confirmation standards can substantially reshape notified disease totals, which is pertinent for understanding surveillance outputs.

Peer reviewed Open access Tuberculosis TreatmentDiagnostics
DOI 10.5694/mja2.70326 ↗

Peritoneal Tuberculosis and Chronic Myeloid Leukaemia: A Case of Hickam's Dictum.

Al-Timimi Z, Chew G, Browne M +1 more

The Medical journal of Australia

Type
Journal article
Scope
Not classified

Why it matters now The case highlights the importance of maintaining diagnostic vigilance for multiple concurrent conditions in complex presentations, particularly when patients do not respond to initial therapy. The limited sensitivity of traditional tuberculosis tests in extrapulmonary disease is demonstrated.

Peer reviewed Open access HIV infectionAIDS Travel medicineDiagnostics
DOI 10.1097/qai.0000000000003843 ↗

High HIV Incidence Among HIV-Infected But Undetected Individuals Seeking HIV Voluntary Counselling and Testing Services in the Greater Masaka Region in Uganda

Obuku Andrew Ekii, Freddie Mukasa Kibengo, Samson Okumu +28 more

JAIDS Journal of Acquired Immune Deficiency Syndromes

Type
Cross-sectional study
Scope
Uganda

Why it matters now The study reports that acute HIV infection can be detected by the GeneXpert HIV-1 Viral Load assay and that incident infection can be estimated without a longitudinal cohort, which the authors frame as relevant to HIV testing and control of new infections in sub-Saharan Africa.

Peer reviewed Open access Malaria DiagnosticsTreatment
DOI 10.1016/j.bios.2026.118956 ↗

A novel capillary-driven dual-mode imaging flow cytometry system for malaria parasite detection and quantification

Suraj K. Maurya, Matt Stark, Alexander Martin Küenzi +4 more

Biosensors and Bioelectronics

Type
Journal article
Scope
Not classified

Why it matters now Malaria disproportionately affects resource-limited tropical and subtropical regions where skilled microscopy operators may be scarce. A low-cost, automated diagnostic tool could reduce dependence on operator expertise and support more consistent parasitemia monitoring in such settings.

Peer reviewed Open access Leishmaniasis DiagnosticsTreatment
DOI 10.1016/j.diagmicrobio.2026.117476 ↗

Retrospective molecular screening reveals Leishmania (Leishmania) infantum in samples from patients investigated for suspected hematological neoplasms

Marcella Silva-Figueiredo, Flávia Cristine Medeiros Theodoro, Fransuellem Batista de Moura Brito +9 more

Diagnostic Microbiology and Infectious Disease

Type
Journal article
Scope
Not classified

Why it matters now The abstract frames differential diagnosis as important in endemic regions due to overlapping clinical and laboratory features between hematological neoplasms and HVL. It suggests incorporating sensitive molecular tools into routine diagnostic workflows may improve etiological clarification and reduce misclassification and inappropriate therapeutic management.

Peer reviewed Open access Hepatitis BChronic hepatitis B TreatmentDiagnostics
DOI 10.1111/jvh.70241 ↗

Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance.

Chabala FW, Sinkala E, Brennan AT +24 more

Journal of viral hepatitis

Type
Journal article
Scope
Not classified

Why it matters now The study supports integrating metabolic comorbidity screening into hepatitis B care and treatment programs across Africa, given the high prevalence of SLD and its association with fibrosis in this population.

Disseminated Mucormycosis and monoclonal gammopathy in a young sarcoidosis patient following COVID-19: A rare case report

Hossam A. Abady, Mohamed M. El-Khatib, Nadine Soliman +6 more

Diagnostic Microbiology and Infectious Disease

Type
Journal article
Scope
Not classified

Why it matters now The authors emphasize the diagnostic and therapeutic difficulty when granulomatous disease, an opportunistic fungal infection, and a hematological abnormality coexist, and stress early recognition and prompt aggressive treatment. Indexing against COVID-19 with diagnostics and treatment topics places it within literature on severe post-COVID-19 opportunistic infection management.

Peer reviewed Open access HIV infectionAIDS TreatmentDiagnostics
DOI 10.1111/myc.70194 ↗

Clinical Impact of Haemophagocytic Lymphohistiocytosis Among Patients With HIV/AIDS and Disseminated Histoplasmosis in a Hyperendemic Region of Northeastern Brazil.

Mota MAL, Sousa MM, Souza JVM +7 more

Mycoses

Type
Journal article
Scope
Brazil

Why it matters now The findings suggest haemophagocytic lymphohistiocytosis is a severe complication in people living with HIV/AIDS with disseminated histoplasmosis and is associated with increased mortality and intensive care needs in this population.

HECA-YOLOv11: A High-Accuracy Hybrid Attention Network for Real-Time Monkeypox Skin Lesion Detection with Interpretability

Xianghong Deng, Chonlatee Photong

Recent Advances in Computer Science and Communications

Type
Journal article
Scope
Not classified

Why it matters now The authors position the model and interface as potential aids for early screening, streamlined clinical workflows, and faster public-health response. These are proposed implications; the abstract does not establish real-world clinical effectiveness or an effect on outbreak incidence.

Peer reviewed Open access TuberculosisHIV infection DiagnosticsTreatment
DOI 10.1016/j.diagmicrobio.2026.117566 ↗

Dual infection: disseminated histoplasmosis and peritoneal tuberculosis in a HIV-negative immunocompetent patient. A case report

Luis Avellano-Khan, Neil Stone, Justin Edwards +2 more

Diagnostic Microbiology and Infectious Disease

Type
Journal article
Scope
United Kingdom

Why it matters now In non-endemic regions, constrained mycological testing may contribute to wrong diagnoses, and concurrent infections pose challenges.

Peer reviewed Open access Melioidosis Diagnostics
DOI 10.1016/j.ijmmb.2026.101274 ↗

Pediatric melioidosis: a scoping review of epidemiology, clinical presentation, management, and outcomes

G. Vithiya, Shunmuga Sundaram Ponnusamy, V. Mangayarkarasi +1 more

Indian Journal of Medical Microbiology

Type
Journal article
Scope
Australia

Why it matters now The compiled evidence points to timely identification and confirmation as factors associated with better survival, and furnishes a basis for future practice and investigation.

Peer reviewed Open access HIV infectionAIDS Diagnostics
DOI 10.1016/j.diagmicrobio.2026.117491 ↗

Rethinking HIV antibody testing in children aged 18-24 months in the OPPTIM study conducted in Johannesburg, South Africa 2018-2021

Lee Fairlie, Shobna Sawry, Jean Le Roux +10 more

Diagnostic Microbiology and Infectious Disease

Type
Journal article
Scope
South Africa

Why it matters now Maternal antibody persistence beyond 18 months creates a meaningful risk of HIV misdiagnosis in uninfected children under the current two-test algorithm used in South Africa. The authors suggest that adding a PCR test to form a three-test algorithm could reduce such misdiagnoses in the 18–24 month age window.

Peer reviewed Open access Melioidosis Diagnostics
DOI 10.1016/j.ijid.2026.109114 ↗

Diagnostic accuracy of the Active Melioidosis Detect Plus rapid test for detection of Burkholderia pseudomallei in throat swabs

Arjun Chandna, Sena Sao, Joy Silisouk +8 more

International Journal of Infectious Diseases

Type
Journal article
Scope
Cambodia, Laos

Why it matters now In endemic areas where throat swab culture is often unavailable, the evaluated rapid test alone is insufficient for melioidosis diagnosis from throat samples.

Strengthening capacity in high-burden malaria-endemic countries: a strategic analysis of training gaps and blended learning solutions in national malaria control programs

Moses Alikali, Graham V. Brown, Samira H. Abdelrahman +1 more

Malaria Journal

Type
Journal article
Scope
Not classified

Why it matters now Authors conclude that targeted capacity building through blended methods is considered essential to improve service delivery and pursuit of elimination goals.

Genomic surveillance meets clinical practice: rule-based individualized treatment prediction for gonorrhoea using SensiTyper

Daniel Golparian, Leonor Sánchez-Busó, Magnus Unemo

Nature Communications

Type
Genomic study
Scope
Not classified

Why it matters now The authors frame extensively drug-resistant gonococci as a threat to empirical therapy and present the tool as supporting antimicrobial stewardship and targeted public health follow-up for XDR isolates.

Peer reviewed Open access SyphilisCongenital syphilis Diagnostics
DOI 10.1071/mj26003 ↗

Antenatal syphilis screening positivity at Port Moresby General Hospital: prevalence, temporal trends, and socio-demographic predictors – a retrospective observational analysis between 2020–2022

Vana Tom, Steven Ketio, Elias Namosha

Papua New Guinea Medical Journal

Type
Journal article
Scope
Papua New Guinea

Why it matters now Positivity exceeded global averages and high-risk subgroups were identified, supporting calls for targeted screening and integration into maternal health efforts toward congenital syphilis elimination in Papua New Guinea.

Peer reviewed Open access Dengue Diagnostics
DOI 10.3389/fcimb.2026.1864621 ↗

Shock index and modified shock index at initial clinical assessment in adults with dengue from Oaxaca, Mexico: sex-based differences in a cross-sectional study

Maricela Martínez Guerra, María Teresa Hernández-Huerta, Eduardo Pérez-Campos +6 more

Frontiers in Cellular and Infection Microbiology

Type
Cross-sectional study
Scope
Mexico

Why it matters now The study adds sex-specific hemodynamic index distributions in adult dengue within a Mexican setting, informing potential refinement of clinical assessment approaches.

Peer reviewed Open access COVID-19SARS TreatmentDiagnostics
DOI 10.2169/internalmedicine.7725-26 ↗

A Case of Recurrent COVID-19 Pneumonia Following Rituximab Therapy: Treatment Informed by a Serial Transbronchial Lung Cryobiopsy, BALF SARS-CoV-2 PCR, and the Clinical Course.

Hayashi J, Nagai T, Seki K +11 more

Internal medicine (Tokyo, Japan)

Type
Journal article
Scope
Not classified

Why it matters now The authors suggest that cryobiopsy histopathology combined with virological findings and clinical course may add complementary information for treatment selection in this type of patient. This is a single-case observation and does not address population-level health outcomes.