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Peer reviewedOpen accessCysticercosisTaeniasis

A qualitative assessment of the context and enabling environment for the control of Taenia solium infections in endemic settings

PLOS Neglected Tropical Diseases·

Nicholas Ngwili, Nancy Johnson, Raphael Wahome, Samuel Githigia, Kristina Roesel, Lian Thomas

DOI
10.1371/journal.pntd.0009470
PMID
34115758
PMCID
PMC8221787
OpenAlex
W3170560381
Study type
Systematic review
Publisher
Public Library of Science (PLoS)
Article type
journal-article
Integrity
current

Why this research matters now

T. solium is a major foodborne disease by burden causing taeniasis, neurocysticercosis, and porcine cysticercosis. The study emphasizes the importance of multi-sectoral collaboration through a One Health approach and may guide future disease control programme research and scale-up.

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Structured evidence summary

Research question

The study examined contextual factors and the enabling environment that influence the success or failure of Taenia solium control programmes in endemic areas.

Study design

A mixed-methods study combining systematic literature review (registered at PROSPERO CRD42019138107, following PRISMA guidelines) with key informant interviews of researchers and implementers from included studies.

Population and setting

The review analyzed 41 publications reporting T. solium control programmes in endemic settings, categorized as efficacy (10), effectiveness (28), and scale-up or implementation (3) studies.

Main findings

Contextual factors identified included epidemiological, socioeconomic, cultural, geographical, environmental, service, organizational, historical, and financial dimensions. The enabling environment was primarily shaped by policies and strategies supporting T. solium control. Failure to consider these contextual factors in target sites led to implementation and evaluation challenges that negatively affected outcomes.

Public-health relevance

T. solium is a major foodborne disease by burden causing taeniasis, neurocysticercosis, and porcine cysticercosis. The study emphasizes the importance of multi-sectoral collaboration through a One Health approach and may guide future disease control programme research and scale-up.

Important limitations

This summary is limited to the supplied single-article abstract and metadata and requires the original paper for decision-grade interpretation.

GIDS interpretation

This systematic review on Taenia solium control contextual factors would be discoverable through queries on taeniasis, cysticercosis, health policy, One Health approaches, or control programme implementation in endemic settings. The study provides methodological guidance rather than surveillance data on disease occurrence.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 9 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseabout diseaseaddresses topicaddresses topicaddresses topichas pathogen typeinforms policy domainstudied population settinguses study design