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Peer reviewedOpen accessInfluenzaH5N1COVID-19

A Systematic Review of New, Enhanced Surveillance Systems and Methodologies for Zoonotic Influenza Viruses in Animals and Human-Animal Interface.

Influenza and other respiratory viruses·

Badra R, Zhang W, Tam JSL, Webby R, Van Der Werf S, Nikisins S, Cullinane A, Gharaibeh S, Njouom R, Peiris M, Kayali G, Heraud JM

DOI
10.1111/irv.70178
PMID
41214450
PMCID
PMC12602164
OpenAlex
W4416202247
Study type
Systematic review
Publisher
Publisher unavailable
Article type
journal-article
Integrity
current

Why this research matters now

Strengthening coordinated monitoring frameworks is presented as essential for reducing seasonal illness impacts and mitigating future outbreak threats through improved diagnostic readiness and targeted research funding.

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Structured evidence summary

Research question

The authors aimed to evaluate recent developments in monitoring techniques for animal and cross-species influenza viruses to determine which innovations warrant broader application and which areas require further investigation.

Study design

This work follows a systematic review framework guided by PRISMA standards, synthesizing data from 164 selected publications out of an initial search yielding 7,490 records.

Population and setting

The scope encompasses global efforts to track influenza strains circulating among wildlife, livestock, and humans, with particular attention to interaction zones where spillover events occur.

Main findings

The analysis identifies multiple technological improvements alongside persistent structural deficiencies in monitoring networks. Current documentation indicates that numerous regions operate without robust cross-sectoral tracking systems, resulting in incomplete estimates of infection prevalence. Priority actions emphasize integrating multi-sectoral datasets, standardizing new testing tools, scaling passive sampling strategies, and aligning technical upgrades with regulatory decision-making.

Public-health relevance

Strengthening coordinated monitoring frameworks is presented as essential for reducing seasonal illness impacts and mitigating future outbreak threats through improved diagnostic readiness and targeted research funding.

Important limitations

The evaluation relies exclusively on indexed academic publications, which may overlook operational field data or reflect uneven research investment across different geographic areas. Additionally, the focus on a seven-year window restricts historical context for long-term trend analysis.

GIDS interpretation

This publication offers a consolidated perspective on methodological evolution within cross-species pathogen tracking initiatives. It contextualizes recent scholarly contributions toward standardized data collection and policy alignment without referencing active epidemiological dashboards or real-time transmission metrics.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 14 auditable classifier relationships to diseases, places, topics, and study design.

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