Eliminating mother-to-child HIV transmission in South Africa
Bulletin of the World Health Organization·
- DOI
- 10.2471/blt.12.106807
- PMID
- 23397353
- PMCID
- PMC3537246
- OpenAlex
- W2154817952
- Study type
- Guideline
- Publisher
- WHO Press
- Article type
- journal-article
- Integrity
- current
Why this research matters now
Demonstrates how coordinated policy adoption and infrastructure expansion can improve preventive care delivery and lower disease burden in high-prevalence regions.
Structured evidence summary
Research question
How can national health systems optimize the deployment of standardized prevention protocols to minimize pediatric viral infections?
Study design
A descriptive program evaluation utilizing longitudinal operational metrics and biennial population surveys to monitor intervention uptake and epidemiological trends.
Population and setting
Pregnant individuals and neonates accessing care through South African public health facilities during a period of expanded national prevention initiatives.
Main findings
Routine molecular screening coverage for infants under two months more than doubled between 2008 and 2011, coinciding with a substantial reduction in estimated transmission percentages. Independent population assessments documented similarly declining infection rates across consecutive survey years. Program enhancements correlated with accelerated guideline dissemination, strengthened institutional partnerships, and broadened diagnostic and therapeutic service availability.
Public-health relevance
Demonstrates how coordinated policy adoption and infrastructure expansion can improve preventive care delivery and lower disease burden in high-prevalence regions.
Important limitations
The provided summary relies exclusively on the supplied abstract and bibliographic metadata, requiring access to the full manuscript for comprehensive methodological assessment and decision-grade interpretation.
GIDS interpretation
This publication targets audiences researching maternal-infant viral prevention frameworks and health system strengthening. Its thematic alignment with policy implementation and transmission monitoring supports retrieval in databases focused on global health interventions and regional epidemiological reports.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 13 auditable classifier relationships to diseases, places, topics, and study design.