Tick-Borne Encephalitis Vaccine Effectiveness and Impact in Slovenia, 2019-2024.
Pathogens (Basel, Switzerland)·
- DOI
- 10.3390/pathogens15050503
- PMID
- 42198629
- PMCID
- PMC13209445
- OpenAlex
- W7160546392
- Study type
- Journal article
- Publisher
- Publisher unavailable
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The data demonstrate significant disease reduction potential through routine immunization, though they simultaneously reveal substantial gaps in current community participation that warrant expanded promotional strategies.
Structured evidence summary
Research question
What is the estimated protective efficacy and population-level impact of tick-borne encephalitis immunization among Slovenian residents?
Study design
An observational evaluation utilizing a screening methodology to compare vaccination proportions between confirmed infection cases and a broader survey cohort across a five-year interval.
Population and setting
Individuals residing in Slovenia, specifically analyzing patients with documented tick-borne encephalitis diagnoses and a separate sample of surveyed adults regarding their immunization status.
Main findings
The analysis determined a ninety-three point four percent protection rate for recipients completing three or more scheduled doses. This coverage level resulted in an estimated four hundred twenty-six avoided infections during the study period, while hypothetical universal adoption projected nearly one thousand additional prevented cases.
Public-health relevance
The data demonstrate significant disease reduction potential through routine immunization, though they simultaneously reveal substantial gaps in current community participation that warrant expanded promotional strategies.
Important limitations
The evaluation is constrained by incomplete immunization documentation for nearly half of the reported infections and utilizes survey-derived denominators rather than exhaustive demographic tracking.
GIDS interpretation
This record supplies historical performance metrics and regional coverage estimates that can inform trend analysis and program planning, serving as a static reference point for epidemiological context.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 11 auditable classifier relationships to diseases, places, topics, and study design.