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Peer reviewedOpen accessCOVID-19SARS

Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings

International Journal of Infectious Diseases·

Mentor Ali Ber Lucien, Michael F. Canarie, Paul E. Kilgore, Gladzdin Jean-Denis, Natael Fénélon, Manise Pierre, Mauricio Cerpa, Gerard A. Joseph, Gina Maki, Marcus J. Zervos, Patrick Dely, Jacques Boncy, Hatim Sati, Ana del Rio, Pilar Ramon-Pardo

DOI
10.1016/j.ijid.2020.12.087
PMID
33434666
PMCID
PMC7796801
OpenAlex
W3120081043
Study type
Commentary
Publisher
Elsevier BV
Article type
journal-article
Integrity
current

Why this research matters now

The commentary emphasizes the need for improved antimicrobial stewardship and infection control in developing countries, and calls for studies to evaluate worldwide antimicrobial resistance evolution during the pandemic, particularly where resistance data are scarce and treatment resources suboptimal.

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Structured evidence summary

Research question

This commentary examines antibiotic consumption and antimicrobial resistance challenges in resource-limited settings during the COVID-19 pandemic, with emphasis on the difficulty of distinguishing bacterial from viral infections and the need for stewardship programs.

Study design

Commentary article discussing clinical and public health challenges related to antibiotic use and antimicrobial resistance in low and middle income countries during the COVID-19 era.

Population and setting

COVID-19 patients in low and middle income countries where diagnostic resources for bacterial pathogen identification are limited and conditions favor pathogen transmission.

Main findings

The abstract notes increased antibiotic consumption globally following COVID-19 dissemination, driven by concerns about bacterial superinfection. It highlights diagnostic challenges in LMIC and observes growing awareness of antimicrobial stewardship and infection prevention measures that may reduce pathogen circulation and antimicrobial resistance dissemination.

Public-health relevance

The commentary emphasizes the need for improved antimicrobial stewardship and infection control in developing countries, and calls for studies to evaluate worldwide antimicrobial resistance evolution during the pandemic, particularly where resistance data are scarce and treatment resources suboptimal.

Important limitations

This summary is limited to the supplied single-article abstract and metadata. The commentary format does not report primary data, and the abstract does not provide explicit study limitations. Full interpretation requires review of the original article.

GIDS interpretation

This article was identified through classifier links for COVID-19, antimicrobial resistance, transmission dynamics, and treatment. As a commentary, it provides expert perspective on antibiotic stewardship challenges in resource-limited settings rather than surveillance or outbreak data.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 10 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseabout diseaseaddresses topicaddresses topicaddresses topicevaluates interventionhas pathogen typestudied population settingstudies pathogenuses study design