Diagnosis and treatment of female genital schistosomiasis
The Lancet Microbe·
- DOI
- 10.1016/j.lanmic.2026.101356
- PMID
- 42127951
- PMCID
- —
- OpenAlex
- W7161108215
- Study type
- Journal article
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
FGS is a neglected tropical disease that affects reproductive health in women and girls in schistosomiasis-endemic regions. Improved diagnosis and treatment strategies are needed to address this sex-specific manifestation of schistosome infection.
Structured evidence summary
Research question
This Series paper examines diagnostic techniques and treatment strategies for female genital schistosomiasis, a condition caused by immunogenic eggs from Schistosoma parasites becoming trapped in genital tissues.
Study design
The paper is a literature review summarizing global evidence on FGS diagnosis and treatment, and introduces a classification framework proposing visual, histological, and molecular subtypes.
Population and setting
The paper addresses women and girls in areas endemic for urogenital schistosomiasis, particularly low-resource settings where FGS predominantly occurs.
Main findings
FGS diagnosis is challenging with currently available methods, especially in low-resource endemic areas. The authors propose three FGS subtypes—visual, histological, and molecular—and emphasize the need for tailored diagnostic and therapeutic strategies given the association with poor reproductive health outcomes.
Public-health relevance
FGS is a neglected tropical disease that affects reproductive health in women and girls in schistosomiasis-endemic regions. Improved diagnosis and treatment strategies are needed to address this sex-specific manifestation of schistosome infection.
Important limitations
This summary is limited to the supplied single-article abstract and metadata. The original paper is required for decision-grade interpretation of the literature synthesis, proposed subtype framework, and treatment recommendations.
GIDS interpretation
The article was classified under Schistosomiasis with topics Diagnostics and Treatment, reflecting its focus on improving clinical management of a sex-specific manifestation of this parasitic disease.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 7 auditable classifier relationships to diseases, places, topics, and study design.