Global search

Find data and evidence

Type at least 2 characters. Use arrow keys to review and Enter to open.

Peer reviewedOpen accessMalariaEchinococcosisSchistosomiasis

Research gaps for three main tropical diseases in the People’s Republic of China

Infectious Diseases of Poverty·

Qi Zheng, Samantha Vanderslott, Bin Jiang, Li-Li Xu, Cong-Shan Liu, Le-Le Huo, Li-Ping Duan, Ning-Bo Wu, Shi-Zhu Li, Zhi-Gui Xia, Wei-Ping Wu, Wei Hu, Hao-Bing Zhang

DOI
10.1186/2049-9957-2-15
PMID
23895635
PMCID
PMC3751495
OpenAlex
W2162797578
Study type
Journal article
Publisher
Springer Science and Business Media LLC
Article type
journal-article
Integrity
current

Why this research matters now

The authors conclude that addressing these research gaps within a short timeframe could enable elimination of all three diseases in mainland China.

01

Structured evidence summary

Research question

The review identifies research gaps for schistosomiasis japonica, malaria, and echinococcosis control programs in mainland China.

Study design

This is a scoping review synthesizing 848 original studies and expert consultations to map knowledge gaps across three tropical disease control programs.

Population and setting

The review addresses disease control in the People's Republic of China, focusing on populations affected by or at risk for the three targeted diseases.

Main findings

For malaria, gaps include inadequate community-level active testing, lack of sensitive diagnostics for asymptomatic cases, and absence of safe mass administration drugs. For schistosomiasis, gaps include inconsistent integrated control policy implementation, ineffective snail control tools, insufficient large-scale diagnostic sensitivity and affordability, and dependence on praziquantel as the sole drug option. For echinococcosis, gaps include limited field epidemiology capacity, insufficient sanitation improvement studies, lack of sensitive early diagnostic tests, and absence of effective short-term treatment drugs.

Public-health relevance

The authors conclude that addressing these research gaps within a short timeframe could enable elimination of all three diseases in mainland China.

Important limitations

This summary is limited to the supplied single-article abstract and metadata. The original paper is required for decision-grade interpretation, including details on review methodology, gap prioritization criteria, and evidence quality assessment.

GIDS interpretation

This scoping review provides context on historical and ongoing research needs for three tropical diseases in China. It describes programmatic challenges and tool deficiencies relevant to national disease control efforts through 2013.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 14 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseabout diseaseaddresses topicaddresses topicaddresses topicaddresses topicevaluates interventionevaluates interventioninforms policy domainstudied instudied population settingstudies populationstudies populationuses study design