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Peer reviewedOpen accessCOVID-19SARS

Australians' attitudes to mRNA vaccination in humans and animals: A cross-sectional survey

Vaccine·

Jane Williams, Chris Degeling, Laura Donovan, Kerrie Wiley

DOI
10.1016/j.vaccine.2026.128907
PMID
42413319
PMCID
OpenAlex
W7167581992
Study type
Cross-sectional study
Publisher
Elsevier BV
Article type
journal-article
Integrity
current

Why this research matters now

The authors highlight the need for vaccine manufacturers and public- and animal-health policymakers to anticipate potentially lower public acceptance of mRNA vaccines and of animal-source foods derived from mRNA-vaccinated livestock, noting that scientific development must be matched by public acceptability for new vaccines to be optimally used.

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Structured evidence summary

Research question

The survey examined Australians' attitudes toward mRNA vaccines compared with conventional vaccines, willingness to receive mRNA vaccination in a future infectious disease emergency, and acceptance of meat and milk from mRNA-vaccinated cattle.

Study design

A cross-sectional, self-administered online survey of Australian adults aged over 18, analysed using descriptive statistics and chi-squared tests.

Population and setting

Adult members of the Australian general public surveyed online, in a national context where new mRNA vaccines are approaching approval.

Main findings

Overall support for vaccination was high, but support for traditionally manufactured vaccines was stronger than for mRNA-based vaccines, which respondents reportedly understood less well. Willingness to accept mRNA vaccination in an emergency was associated with voluntariness, understanding, and higher trust. Support for consuming meat and milk from mRNA-vaccinated cattle was mixed, reflecting limited familiarity with animal vaccination.

Public-health relevance

The authors highlight the need for vaccine manufacturers and public- and animal-health policymakers to anticipate potentially lower public acceptance of mRNA vaccines and of animal-source foods derived from mRNA-vaccinated livestock, noting that scientific development must be matched by public acceptability for new vaccines to be optimally used.

Important limitations

This summary is limited to the supplied single-article abstract and bibliographic metadata; the original paper, including its full methods and any explicit limitations, is required for decision-grade interpretation.

GIDS interpretation

The study addresses the discoverability of public sentiment around mRNA vaccines in Australia and comparator contexts, and could inform situational awareness of vaccine acceptance, but it does not constitute or confirm any live surveillance signal.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 12 auditable classifier relationships to diseases, places, topics, and study design.

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