Peer reviewedHistorical baselineAIDSHIV infection

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).

Science (New York, N.Y.)·May 20, 1983

Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, Dauguet C, Axler-Blin C

Why this research matters now

A landmark paper in the identification of the retrovirus later central to HIV/AIDS surveillance and diagnostics.

Structured evidence summary

Could a retrovirus be isolated from a patient at risk for AIDS?

Laboratory investigation.

This field has not yet received a quality-gated evidence summary. Consult the original article.

This field has not yet received a quality-gated evidence summary. Consult the original article.

Anchors the historical shift from syndrome-based AIDS reporting toward pathogen-specific HIV diagnostics.

Limitations could not be fully assessed from the available metadata.

Use as historical context for HIV/AIDS surveillance definitions and laboratory confirmation.

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

This article has 6 auditable classifier relationships to diseases, places, topics, and study design.

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