Clinical features and viral load variations of Mpox: a retrospective study in Chongqing, China
BMC Infectious Diseases·
- DOI
- 10.1186/s12879-024-09537-0
- PMID
- 38926635
- PMCID
- PMC11202379
- OpenAlex
- W4400060163
- Study type
- Journal article
- Publisher
- Springer Science and Business Media LLC
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The authors position the work as relevant to targeted prevention, control, and treatment planning for mpox in MSM and people living with HIV. The abstract also frames the sampling results as supporting attention to direct physical contact, especially at genital and anal sites, in the study context.
Structured evidence summary
Research question
The study asks what clinical characteristics and viral load patterns were seen in mpox patients in Chongqing, with attention to MSM and people living with HIV, and whether those findings could inform prevention and control planning.
Study design
This is a retrospective observational study of patients admitted to a single public health medical center over September 2022 to October 2023. Clinical features were reviewed and Mpox virus was detected with qPCR from collected samples.
Population and setting
The setting was the Chongqing Public Health Medical Center in Chongqing, Southwest China. The reported cases were nine male patients, all in the MSM population, and seven were living with HIV while on effective ART with viral suppression.
Main findings
Among the nine reported infections, the authors did not observe clear clinical differences between MSM patients with and without HIV, and no deaths occurred. Viral load was reported as higher in skin samples than in throat, nasopharyngeal, blood, or semen samples.
Public-health relevance
The authors position the work as relevant to targeted prevention, control, and treatment planning for mpox in MSM and people living with HIV. The abstract also frames the sampling results as supporting attention to direct physical contact, especially at genital and anal sites, in the study context.
Important limitations
No explicit limitations are stated in the supplied abstract. The summary is therefore limited to the supplied single-article abstract and metadata, and the original paper would be needed for decision-grade interpretation; the study is also based on only nine infections from one center.
GIDS interpretation
This record is discoverable as a peer-reviewed mpox clinical study from China and is indexed around monkeypox, transmission dynamics, travel medicine, and treatment. It provides literature context for mpox in MSM and PLWH, but the supplied record alone does not establish a live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 11 auditable classifier relationships to diseases, places, topics, and study design.