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Peer reviewedOpen accessRabies

Designing Programs for Eliminating Canine Rabies from Islands: Bali, Indonesia as a Case Study

PLoS Neglected Tropical Diseases·

Sunny E. Townsend, I Putu Sumantra, Pudjiatmoko, Gusti Ngurah Bagus, Eric Brum, Sarah Cleaveland, Sally Crafter, Ayu P. M. Dewi, Dewa Made Ngurah Dharma, Jonathan Dushoff, Janice Girardi, I Ketut Gunata, Elly F. Hiby, Corlevin Kalalo, Darryn L. Knobel, I Wayan Mardiana, Anak Agung Gde Putra, Luuk Schoonman, Helen Scott–Orr, Mike Shand, I Wayan Sukanadi, Pebi Purwo Suseno, Daniel T. Haydon, Katie Hampson

DOI
10.1371/journal.pntd.0002372
PMID
23991233
PMCID
PMC3749988
OpenAlex
W2004359489
Study type
Journal article
Publisher
Public Library of Science (PLoS)
Article type
journal-article
Integrity
current

Why this research matters now

The findings provide practical guidance for rabies elimination programs on islands and contribute to the global strategy for canine rabies elimination, emphasizing the need for comprehensive, repeated, high-coverage vaccination campaigns with full regional cooperation.

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Structured evidence summary

Research question

The study examined the effectiveness of different control strategies for eliminating canine rabies from Bali, Indonesia, following a 2008 epidemic.

Study design

The authors estimated the basic reproductive number from epidemic data and developed a model to compare mass dog vaccination scenarios.

Population and setting

The study focused on the domestic dog population on the Indonesian island of Bali following a rabies epidemic that began in 2008 and resulted in over 100 human deaths.

Main findings

The basic reproductive number for rabies in dogs was estimated at approximately 1.2, similar to estimates from populations with ten-fold lower dog density, indicating that achievable reductions in dog density would not effectively control rabies. High-coverage mass vaccination was identified as the most important factor for elimination, with omission of even small areas reducing the probability of success.

Public-health relevance

The findings provide practical guidance for rabies elimination programs on islands and contribute to the global strategy for canine rabies elimination, emphasizing the need for comprehensive, repeated, high-coverage vaccination campaigns with full regional cooperation.

Important limitations

This summary relies on the supplied single-article abstract and metadata. The original paper is required for decision-grade interpretation of model assumptions, data quality, generalizability beyond island settings, and operational feasibility of recommended vaccination coverage levels.

GIDS interpretation

The article was classified under Rabies, Indonesia, One Health, Transmission dynamics, Vaccination, and Climate and environment topics, reflecting its focus on zoonotic disease control strategy and mathematical modeling of an island epidemic.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 9 auditable classifier relationships to diseases, places, topics, and study design.

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