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Peer reviewedOpen accessEbola

Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale

PLOS Neglected Tropical Diseases·

Larisa Lee-Cruz, Maxime Lenormand, Julien Cappelle, Alexandre Caron, Hélène De Nys, Martine Peeters, Mathieu Bourgarel, François Roger, Annelise Tran

DOI
10.1371/journal.pntd.0009683
PMID
34424896
PMCID
PMC8425568
OpenAlex
W3196281824
Study type
Journal article
Publisher
Public Library of Science (PLoS)
Article type
journal-article
Integrity
current

Why this research matters now

The authors frame GIS-MCE suitability maps as an updatable tool to support surveillance and prevention of future Ebola outbreaks as new knowledge becomes available.

01

Structured evidence summary

Research question

The study examines where environmental, climatic, and anthropogenic conditions may be suitable for Ebola virus spillover to humans at a landscape scale across regions with prior emergence.

Study design

A knowledge-driven Geographic Information System-based multicriteria evaluation (GIS-MCE) was applied, combining literature-derived risk factors into geographical data layers to produce suitability maps, with sensitivity analysis to test robustness.

Population and setting

Guinea, the Republic of the Congo, and Gabon were the focus regions, selected as areas where Ebola viruses had previously emerged.

Main findings

Suitability maps displayed marked spatial and temporal variability at fine regional scales. Reported spillover events were located in areas of intermediate to high suitability, and sensitivity analysis indicated the maps were robust.

Public-health relevance

The authors frame GIS-MCE suitability maps as an updatable tool to support surveillance and prevention of future Ebola outbreaks as new knowledge becomes available.

Important limitations

The authors explicitly note important remaining gaps in knowledge about factors associated with Ebola virus spillover risk. Additionally, this summary is limited to the supplied single-article abstract/metadata and requires the original paper for decision-grade interpretation.

GIDS interpretation

The work provides a landscape-scale suitability mapping approach that could complement Ebola-related discoverability efforts, but the abstract does not connect the model output to any active surveillance signal.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 10 auditable classifier relationships to diseases, places, topics, and study design.

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