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Guinea research

Published infectious-disease research classified with a high-confidence geographic relationship to Guinea.

Published evidence
10
Diseases
10
Countries
15
Topics
9

Evidence stream

Published literature

10

10 publications

Surveillance without silos: a One Health data imperative for avian influenza in West Africa

Emmanuel Musa, Francis Akpa, Godfred O. Boateng

Frontiers in Cellular and Infection Microbiology

Type
Journal article
Scope
Benin, Ghana, Guinea

Why it matters nowThe paper presents integrated surveillance as relevant to preparedness and to earlier detection and response for human or animal health threats in West Africa. This relevance is framed as an operational and preparedness priority in the abstract.

One Health Prioritization of Rabies Risk in the Republic of Guinea: Integration of Human Knowledge, Canine Immunity, and Spatial Analysis

Noumouké Kante, Abdoulaye Kuan Traore, Lanceï Kaba +2 more

Tropical Medicine and Infectious Disease

Type
Journal article
Scope
Guinea

Why it matters nowAchieving effective population-level protection requires synchronized efforts that address both animal immunization gaps and community educational needs. Aligning intervention tactics with localized risk profiles could optimize resource distribution for zoonotic disease mitigation.

Peer reviewedOpen accessLassaHemorrhagic FeverTreatment
DOI 10.1128/mbio.00880-26 ↗

Lassa fever and Argentine hemorrhagic fever treatment in guinea pigs using broad-spectrum cap-dependent endonuclease inhibitors

Junki Maruyama, Satoshi Taniguchi, Takeshi Saito +16 more

mBio

Type
Journal article
Scope
Guinea

Why it matters nowThese viruses trigger severe human hemorrhagic illnesses with substantial mortality and scarce treatment alternatives. The observed cross-reactive antiviral properties indicate potential utility for developing broader therapeutic options.

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Connor Weidle, Natalie Brunette, Samuel P. Wrenn +17 more

Nature Communications

Type
Journal article
Scope
Sudan, Democratic Republic of the Congo, Guinea

Why it matters nowFindings support continued development of a pan-ebolavirus vaccine built on the I53-50 platform, which has established clinical safety, and may be relevant for populations at risk of EBOV and SUDV outbreaks.

Nosocomial Outbreak of Lassa Fever in Conakry, Guinea, 2022.

Annibaldis G, Soropogui B, Ifono K +26 more

The Journal of infectious diseases

Type
Journal article
Scope
Guinea

Why it matters nowThe abstract frames the outbreak as evidence that healthcare facilities in areas considered lower risk may still face nosocomial Lassa virus transmission in the context of human movement. It also emphasizes the operational relevance of rapid diagnostics, genomic analysis, and ecological investigation for outbreak response.

Policy uptake and implementation of the RTS,S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years following the WHO recommendation

Caroline Bonareri Osoro, Eleanor Ochodo, Titus K Kwambai +7 more

BMJ Global Health

Type
Journal article
Scope
Burkina Faso, Cameroon, Ghana

Why it matters nowTwenty of thirty countries applying for vaccine support received financial approval from the Global Alliance for Vaccines and Immunization as of March 2024, demonstrating widespread interest. However, limited RTS,S/AS01 availability prevents some approved countries from receiving required doses, raising vaccine equity concerns.

Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale

Larisa Lee-Cruz, Maxime Lenormand, Julien Cappelle +6 more

PLOS Neglected Tropical Diseases

Type
Journal article
Scope
Democratic Republic of the Congo, Gabon, Guinea

Why it matters nowThe authors frame GIS-MCE suitability maps as an updatable tool to support surveillance and prevention of future Ebola outbreaks as new knowledge becomes available.

Ebola Virus Infection Associated with Transmission from Survivors

Saskia Den Boon, Barbara J. Marston, Tolbert G. Nyenswah +16 more

Emerging Infectious Diseases

Type
Journal article
Scope
Guinea, Liberia, Sierra Leone

Why it matters nowThe findings underscore the continued importance of Ebola survivor services, sustained surveillance, and response capacity in regions previously affected by widespread transmission.

Ebola virus disease in West Africa--the first 9 months of the epidemic and forward projections.

WHO Ebola Response Team, Aylward B, Barboza P +5 more

The New England journal of medicine

Type
Mathematical modelling
Scope
Guinea, Liberia, Sierra Leone

Why it matters nowA central West Africa Ebola epidemic analysis connecting case surveillance with forward projections.

The Infectiousness of Tuberculosis Patients Coinfected with HIV

A. Roderick Escombe, David A. J Moore, Robert H Gilman +10 more

PLoS Medicine

Type
Journal article
Scope
Guinea

Why it matters nowThe authors emphasise rapid drug-susceptibility testing to guide effective treatment and prioritising TB infection control and environmental measures in crowded health-care settings to prevent dissemination of drug-resistant TB.