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Peer reviewedOpen accessMalaria

Cost-effectiveness of malaria internittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania

Bulletin of the World Health Organization·

Guy Hutton

DOI
10.2471/blt.08.051961
PMID
19274364
PMCID
PMC2636201
OpenAlex
W2097667956
Study type
Journal article
Publisher
WHO Press
Article type
journal-article
Integrity
current

Why this research matters now

The paper is relevant to malaria prevention in infants and to economic evaluation of a preventive intervention delivered through routine immunization services. It may help readers compare value-for-money estimates across program settings.

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Structured evidence summary

Research question

The article asks whether intermittent preventive treatment in infants with sulfadoxine-pyrimethamine is cost-effective in two IPTi trial settings in Mozambique and Tanzania.

Study design

This is an economic evaluation using results from two prior IPTi trials. The abstract describes estimation of episodes prevented, DALYs averted, deaths averted, and intervention costs.

Population and setting

The setting was infants younger than 9 months in Ifakara, United Republic of Tanzania, and Manhiça, Mozambique. IPTi was delivered through the Expanded Programme on Immunization.

Main findings

The abstract reports cost per malaria episode averted of US$ 1.57 in Ifakara and US$ 4.73 in Manhiça. It also reports cost per DALY averted of US$ 3.7 and US$ 11.2, respectively, and cost per death averted of US$ 100.2 and US$ 301.1. The authors conclude that IPTi with SP is expected to improve health in a cost-effective way and offer good value for public health programmes.

Public-health relevance

The paper is relevant to malaria prevention in infants and to economic evaluation of a preventive intervention delivered through routine immunization services. It may help readers compare value-for-money estimates across program settings.

Important limitations

No explicit limitations are stated in the abstract. This summary is therefore limited to the supplied single-article abstract and metadata, and the original paper would be needed for decision-grade interpretation.

GIDS interpretation

This record is discoverable as a peer-reviewed WHO Bulletin article on malaria prevention economics in infants, with relevance to Tanzania and Mozambique. It provides literature context only and should not be read as evidence of a live surveillance signal.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 9 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicevaluates interventionstudied instudied instudied population settingstudies populationuses study design