Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024
International Journal of Infectious Diseases·
- DOI
- 10.1016/j.ijid.2025.107940
- PMID
- 40449873
- PMCID
- —
- OpenAlex
- W4410845460
- Study type
- Journal article
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The authors describe the reported outbreak as indicating a need for greater investment in dengue research, vaccine development, vector control, and therapeutic strategies. They also recommend adding dengue virus infection to the WHO Research and Development Priority Disease list.
Structured evidence summary
Research question
What was the global dengue burden reported during 2024, and which country-level factors were associated with dengue-related mortality?
Study design
The study analysed monthly dengue cases and deaths reported through the WHO global surveillance system from 1 January through 31 December 2024. It used a country-level generalised linear regression model to assess factors associated with dengue-related mortality.
Population and setting
The analysis covered countries contributing dengue case and death reports to the WHO global surveillance system during 2024.
Main findings
The study reports 14.1 million dengue cases and 9,508 dengue-related deaths globally in 2024, with a reported case-fatality rate of 0.07%. Higher dengue-related mortality per million population was statistically associated with Southern Hemisphere location, a larger aged population, and higher mean annual temperature.
Public-health relevance
The authors describe the reported outbreak as indicating a need for greater investment in dengue research, vaccine development, vector control, and therapeutic strategies. They also recommend adding dengue virus infection to the WHO Research and Development Priority Disease list.
Important limitations
The findings rely on cases and deaths reported through a global surveillance system and on country-level regression analysis, so the abstract does not establish how reporting completeness or aggregate-level measurement may affect the estimates. No further limitations are stated; this summary is limited to the supplied single-article abstract and metadata and requires the original paper for decision-grade interpretation.
GIDS interpretation
The article is discoverable as evidence concerning dengue outbreak investigation, surveillance, vaccination, treatment, and climate and environmental factors. Its supplied abstract provides global 2024 reporting estimates and an associated-factor analysis, but does not by itself establish a connection to any live surveillance signal.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 16 auditable classifier relationships to diseases, places, topics, and study design.