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Peer reviewedOpen accessAIDS

Clinical Epidemiology and Health Systems Determinants of HIV/AIDS Care Outcomes in Port Harcourt Local Government Area, Rivers State, Nigeria

International Journal of TROPICAL DISEASE & Health·

Nduye Christie Tobin Briggs, Ifeoma Christiana Nwadiuto

DOI
10.9734/ijtdh/2026/v47i81775
PMID
PMCID
OpenAlex
W7203728112
Study type
Journal article
Publisher
Sciencedomain International
Article type
journal-article
Integrity
current

Why this research matters now

The 68.3% viral suppression rate falls meaningfully short of the 95-95-95 global target, with facility-type disparities indicating actionable gaps in differentiated service delivery supply chains, mental health integration, and private-sector surveillance reporting that directly affect HIV epidemic control in urban Nigeria.

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Structured evidence summary

Research question

The study examined clinical epidemiology and health systems determinants of HIV care outcomes, specifically viral suppression, across different facility types in Port Harcourt Local Government Area, Rivers State, Nigeria.

Study design

A convergent parallel mixed-methods study combined a cross-sectional survey of 542 people living with HIV using validated tools with 12 key informant interviews from clinicians, adherence counselors, and pharmacists across eight facilities (public tertiary, model primary health centers, and private facilities). Multivariable logistic regression identified predictors of viral suppression.

Population and setting

The study enrolled 542 people living with HIV receiving care across eight facilities in Port Harcourt Local Government Area, Rivers State, Nigeria. Participants had a mean age of 35.2 years, 62.4% were female, and represented patients from public tertiary, model primary health center, and private facility types.

Main findings

Overall viral suppression was 68.3%, below the 95% target. Independent predictors of suppression included older age, female sex, high adherence, treatment buddy support, and differentiated service delivery enrollment, while depression, stigma, and private facility attendance reduced suppression odds. System gaps included limited mental health screening (25% of facilities), ART stockouts (37.5% of facilities), absent private-sector electronic medical record transmission, and uneven differentiated service delivery implementation.

Public-health relevance

The 68.3% viral suppression rate falls meaningfully short of the 95-95-95 global target, with facility-type disparities indicating actionable gaps in differentiated service delivery supply chains, mental health integration, and private-sector surveillance reporting that directly affect HIV epidemic control in urban Nigeria.

Important limitations

This summary relies on the supplied single-article abstract and metadata. The cross-sectional design cannot establish causality between predictors and viral suppression, and generalizability beyond Port Harcourt Local Government Area is uncertain. Complete assessment of study limitations requires access to the full published article.

GIDS interpretation

The article was classified under AIDS surveillance and treatment topics for Nigeria, making it discoverable for monitoring HIV care cascades, health system performance, and viral suppression outcomes in urban South-South Nigeria. The facility-type comparisons and health systems determinants analysis add context for interpreting surveillance data on HIV treatment program effectiveness.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 8 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicevaluates interventionstudied instudied population settingstudies pathogenuses study design