百日咳是一种高度传染性、可疫苗预防的细菌性呼吸道疾病,由百日咳博德特菌引起,大多数人类疾病归因于该菌,部分疾病由副百日咳博德特菌引起 [1][2][3]。人类是已确认的 B. pertussis 的唯一宿主物种 [1]。潜伏期通常为七至十天 [1]。
疾病概览
细菌性百日咳
Pertussis
百日咳(又称 whooping cough)是一种高度传染性细菌性呼吸道疾病,主要由百日咳博德特菌引起,并可通过疫苗接种预防 [1][2][3]。疾病通常以类似感冒的症状开始,并可进展为持续性阵发性咳嗽、鸡鸣样回声和咳嗽后呕吐 [1][2][4]。该病仍为地方性流行,已在全球出现回升,报告的疾病负担已转向年龄较大的儿童和成人,而婴儿仍然特别易感 [1][5]。疫苗接种是主要的公共卫生预防策略,但免疫力可减弱,且百日咳仍持续存在于已接种人群中 [1][2]。
阅读完整临床与流行病学资料7
百日咳的潜伏期通常为七至十天,初期症状类似普通感冒,表现为轻度发热、流涕与轻微咳嗽[2][1]。随后病情进展为阵发性剧烈咳嗽,可持续一至六周甚至更久,咳嗽发作后常伴有特征性的高调吸气性哮声[2][1]。剧烈咳嗽可导致疲劳、呕吐及肋骨骨折;一岁以下婴儿可能缺乏典型咳嗽而仅表现为呼吸暂停[1]。此外,肺炎是相对常见的并发症,惊厥与脑部病变则较为罕见[2]。
百日咳在全球范围内呈地方性流行,2018年全球报告病例逾十五万例,但实际感染规模因漏报和诊断不足被显著低估[1]。据估计,全球每年疾病负担约达两千四百万例,其中幼童死亡人数约十六万,且九成以上病例集中于发展中国家[1]。近二十年来,尽管儿童普遍接种疫苗,多国仍报告疫情回升,且疾病呈现每三至五年一次的周期性暴发特征[5][1]。随着时间推移,主要感染人群已从婴幼儿扩展至学龄儿童与成人,这些群体逐渐成为新生儿等高危人群的主要传染源[5]。
百日咳是一种高度传染性的呼吸道感染,主要通过咳嗽或打喷嚏产生的飞沫在人与人之间轻易传播 [2]。人类是 B. pertussis 的唯一宿主物种,动物园黑猩猩和野生大猩猩的感染被认为可能通过与人类密切接触获得 [1]。
因疫苗接种而获得的免疫力已减弱的个体仍处于风险之中,因为百日咳已持续存在于已接种人群中,且疫情回升被归因于免疫力减弱 [1]。疫苗接种广泛的西方国家人群也仍然受到影响,在这些国家,百日咳是最常见的可疫苗预防疾病之一 [1]。
百日咳预防主要依靠疫苗接种,疫苗有效且被世界卫生组织和美国疾病控制与预防中心推荐用于常规使用;多组分无细胞疫苗估计有效率为71–85%,对更严重菌株的保护效果更高 [1]。保护效果随时间下降,因此通常建议年龄较大的儿童和成人接种额外剂次 [1]。为孕妇接种是一项有利的策略,有望预防一岁以内婴儿的百日咳病例、住院和死亡 [3]。尽管疫苗接种广泛,百日咳仍持续存在于已接种人群中,并且仍是西方国家最常见的可疫苗预防疾病之一 [1]。
- 1Wikipedia contributors. Whooping cough - Wikipedia [Internet]. Wikipedia. cited 3 Sept 2026.Available from: https://en.wikipedia.org/wiki/Whooping_cough
- 2World Health Organization. Pertussis [Internet]. cited 3 Sept 2026.Available from: https://www.who.int/health-topics/pertussis
- 3Nieves DJ et al. Bordetella pertussis. Microbiol Spectr. 2016 Jun. PMID: 27337481. doi: 10.1128/microbiolspec.EI10-0008-2015.PubMed: https://pubmed.ncbi.nlm.nih.gov/27337481/
- 4Kinkade S et al. Acute Bronchitis. Am Fam Physician. 2016 Oct 1. PMID: 27929206.PubMed: https://pubmed.ncbi.nlm.nih.gov/27929206/
- 5Mi YM et al. Expert consensus for pertussis in children: new concepts in diagnosis and treatment. World J Pediatr. 2024 Dec. PMID: 39537933. doi: 10.1007/s12519-024-00848-5.PubMed: https://pubmed.ncbi.nlm.nih.gov/39537933/
- 6Locht C et al. Pertussis before, during and after Covid-19. EMBO Mol Med. 2025 Apr. PMID: 39994481. doi: 10.1038/s44321-025-00199-2.PubMed: https://pubmed.ncbi.nlm.nih.gov/39994481/
- A37
- CA01
数据覆盖
报告国家和地区
各报告国家的趋势
月度变化趋势
研究雷达
近期相关研究
Parent-driven transmission, off-label SMZ-TMP, and severe pertussis prediction in infants under 2 months: a real-world observational cohort of 527 cases
Frontiers in Pediatrics
Post-marketing safety surveillance of tetanus, diphtheria, and acellular pertussis (Tdap) vaccine: a disproportionality analysis of the vaccine adverse event reporting system (2015–2025)
Frontiers in Cellular and Infection Microbiology
Multicenter Study on Children With Bordetella parapertussis Infections
Pediatric Infectious Disease Journal
Safety of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in USA and Puerto Rico: Results from a Phase III, randomized, active-controlled study.
Human vaccines & immunotherapeutics
Updated Assessment of the Impact of the Modified Council of State and Territorial Epidemiologists Case Definition for Pertussis on Reported Pertussis
Clinical Infectious Diseases
显示 25 篇相关论文中的 5 篇。
文献链接仅用于发现研究,不会改变或验证上方的监测序列。
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官方数据来源机构、频率与说明119
Austria AGES Radar for Infectious Diseases
Austria
AGES Radar monthly national source. Internal ingestion retains native categories; public release is disabled pending licence review.
Australia NINDSS
Australia
Australian national notifiable diseases surveillance dashboard.
Australia NINDSS — Australian Capital Territory
Australian Capital Territory, Australia
Australian NINDSS monthly state/territory notifications for Australian Capital Territory, kept separate from the Australia national aggregate.
Australia NINDSS — New South Wales
New South Wales, Australia
Australian NINDSS monthly state/territory notifications for New South Wales, kept separate from the Australia national aggregate.
Australia NINDSS — Northern Territory
Northern Territory, Australia
Australian NINDSS monthly state/territory notifications for Northern Territory, kept separate from the Australia national aggregate.
Australia NINDSS — Queensland
Queensland, Australia
Australian NINDSS monthly state/territory notifications for Queensland, kept separate from the Australia national aggregate.
Australia NINDSS — South Australia
South Australia, Australia
Australian NINDSS monthly state/territory notifications for South Australia, kept separate from the Australia national aggregate.
Australia NINDSS — Tasmania
Tasmania, Australia
Australian NINDSS monthly state/territory notifications for Tasmania, kept separate from the Australia national aggregate.
Australia NINDSS — Victoria
Victoria, Australia
Australian NINDSS monthly state/territory notifications for Victoria, kept separate from the Australia national aggregate.
Australia NINDSS — Western Australia
Western Australia, Australia
Australian NINDSS monthly state/territory notifications for Western Australia, kept separate from the Australia national aggregate.
ECDC Surveillance Atlas — Belgium Annual Baseline
Belgium
Belgium annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Bulgaria Annual Baseline
Bulgaria
Bulgaria annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Brazil DATASUS SINAN
Brazil
Brazil Ministry of Health DATASUS/SINAN public DBC microdata aggregated to national monthly notification counts.
Canada PHAC CNDSS Annual
Canada
Canada is the national jurisdiction; subdivision feeds are registered separately.
Public Health Ontario IDTO Monthly
Ontario, Canada
Ontario-level current-year preliminary monthly case counts from Public Health Ontario's IDTO report.
China CDC Weekly
China
Monthly notifiable infectious disease reports published by China CDC.
National Disease Control and Prevention Administration
China
Official China public health bulletin and query portal.
PubMed
China
Biomedical literature discovery feed used as supplementary context.
Public Health Science Data Center
Anhui, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Anhui, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Beijing, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Beijing, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Chongqing, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Chongqing, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Fujian, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Fujian, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Guangdong, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Guangdong, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Gansu, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Gansu, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Guangxi, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Guangxi, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Guizhou, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Guizhou, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Henan, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Henan, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Hubei, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Hubei, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Hebei, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Hebei, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Hainan, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Hainan, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Heilongjiang, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Heilongjiang, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Hunan, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Hunan, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Jilin, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Jilin, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Jiangsu, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Jiangsu, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Jiangxi, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Jiangxi, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Liaoning, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Liaoning, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Inner Mongolia, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Inner Mongolia, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Ningxia, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Ningxia, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Qinghai, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Qinghai, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Sichuan, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Sichuan, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Shandong, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Shandong, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Shanghai, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Shanghai, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Shaanxi, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Shaanxi, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Shanxi, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Shanxi, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Tianjin, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Tianjin, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Xinjiang, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Xinjiang, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Tibet, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Tibet, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Yunnan, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Yunnan, China
Province-level statutory infectious disease report published by the responsible health authority.
Public Health Science Data Center
Zhejiang, China
Chinese province-level historical monthly observations; this higher-priority source overlays overlapping official monthly reports.
Provincial statutory infectious disease monthly report
Zhejiang, China
Province-level statutory infectious disease report published by the responsible health authority.
ECDC Surveillance Atlas — Cyprus Annual Baseline
Cyprus
Cyprus annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Czechia Annual Baseline
Czechia
Czechia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Germany RKI SurvStat 2.0
Germany
RKI SurvStat national weekly notification export; raw ZIP exports are retained and recent weeks are overwritten for revisions.
ECDC Surveillance Atlas — Denmark Annual Baseline
Denmark
Denmark annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Estonia Annual Baseline
Estonia
Estonia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Spain Annual Baseline
Spain
Spain annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Finland THL Infectious Diseases Register
Finland
Finland THL Infectious Diseases Register national monthly case counts. The current month is ingested as provisional and the latest three months are refreshed for source revisions.
ECDC Surveillance Atlas — France Annual Baseline
France
France annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — United Kingdom Annual Baseline
United Kingdom
United Kingdom annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Greece Annual Baseline
Greece
Greece annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Hong Kong, China CHP Notifiable Diseases
Hong Kong, China
Hong Kong, China CHP annual notifiable infectious disease CSVs normalized to national monthly totals
ECDC Surveillance Atlas — Croatia Annual Baseline
Croatia
Croatia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Hungary Annual Baseline
Hungary
Hungary annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Ireland HPSC Notifiable Diseases Hub
Ireland
Ireland HPSC national weekly notifiable-disease totals from the official ArcGIS FeatureServer. Internal ingestion is enabled; public release remains disabled pending written redistribution permission.
冰岛卫生署年度传染病看板
Iceland
冰岛全国分病种年度病例通报;历史值可能追溯修订,并保持年度总量口径。
冰岛卫生署性病监测看板
Iceland
实验室与登记监测的月度性病诊断事实;官方看板按季度发布。
冰岛卫生署呼吸道感染周度看板
Iceland
按 ISO 周记录的呼吸道疾病诊断数;住院、样本和疫苗指标不计入诊断数。
冰岛卫生署历史传染病登记
Iceland
1997—2021 年官方历史登记表,年度与月度事实按原始粒度保留。
冰岛卫生署历史 ICD 临床月报
Iceland
Saga 电子病历 ICD 就诊数;与登记通报不可比并保持独立。
ECDC Surveillance Atlas — Italy Annual Baseline
Italy
Italy annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
日本 NIID/JIHS 周报
Japan
日本 NIID/JIHS 周度传染病监测数据。
Korea KDCA EID
South Korea
Korea KDCA notifiable infectious disease OpenAPI or portal/KOSIS downloads aggregated to national monthly notification counts.
ECDC Surveillance Atlas — Lithuania Annual Baseline
Lithuania
Lithuania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Luxembourg Annual Baseline
Luxembourg
Luxembourg annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Latvia Annual Baseline
Latvia
Latvia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Malta Annual Baseline
Malta
Malta annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Netherlands Annual Baseline
Netherlands
Netherlands annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Norway FHI MSIS Statistics Bank
Norway
Norway FHI MSIS national monthly notifications from the official Allvis frontend API; adapter contract checks guard the unversioned endpoint.
New Zealand PHF Science Monthly Notifiable Diseases
New Zealand
PHF Science (formerly ESR) monthly notifiable disease surveillance data via internal globalID2 crawler
ECDC Surveillance Atlas — Poland Annual Baseline
Poland
Poland annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Portugal Annual Baseline
Portugal
Portugal annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Romania Annual Baseline
Romania
Romania annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Sweden Public Health Agency SmiNet
Sweden
Sweden SmiNet national monthly reported cases from the official Public Health Agency statistics pages; public release is enabled with closed-month publication and revisable recent-month refreshes.
Singapore CDA Weekly Infectious Diseases Bulletin
Singapore
Singapore national weekly case notifications, combining the official data.gov.sg 2012–2022 CSV history with CDA annual workbooks from 2023 onward; 2023 weekly PDFs are retained as a source fallback.
ECDC Surveillance Atlas — Slovenia Annual Baseline
Slovenia
Slovenia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
ECDC Surveillance Atlas — Slovakia Annual Baseline
Slovakia
Slovakia annual Member-State reported case counts from the ECDC Surveillance Atlas. Missing topic/year cells remain unknown and published zeroes are preserved. Data provided by ECDC based on data reported by EU/EEA Member States.
Taiwan, China CDC NIDSS
Taiwan, China
Taiwan, China monthly notifiable infectious disease open-data CSV feed.
US CDC NNDSS
United States
CDC National Notifiable Diseases Surveillance System provisional data.
US CDC NHSS HIV
United States
CDC NNDSS weekly data plus NHSS annual national HIV diagnoses