Safety and efficacy of the monoclonal antibody L9LS for malaria prevention in children exposed to perennial malaria transmission in Kenya: a randomised, double-blind, placebo-controlled, phase 2 trial

The Lancet·2026年4月1日

Laura C Steinhardt, Titus K Kwambai, Martina Oneko, Eunice Ouma, Ruth Njoroge, Viviane Callier, Zonghui Hu, Julie R Gutman, Reuben Yego, Kephas Otieno, Kelvin Onoka, Lilian Otieno, Kennedy Oduol, Leonid Serebryannyy, Bob C Lin, Will Adams, Somia Hickman, Anne C Preston, Kevin Carlton, Michael Holdsworth, Yan Xiao, Feiko O ter Kuile, Wycliffe Odongo, Sean C Murphy, Tuan M Tran, Simon Kariuki, Peter D Crompton, Robert A Seder, Steven Achieng, Fredrick Adhola, Eliakim Agono, Elizabeth Ambululi, Lynn Amondi, Mary Awuor, Benard Ayatta, Dennis Bii, Lilian Chemada, Linedi Chemwok, Miriam Chomba, Gentrix Indoshi, Lwanga Karoli, Martha Kimungui, Franklin Komino, Nypha M’mayi, Judy Magoma, Sharon N’getich, George N’gonga, Nancy Nyamache, Joshua Obiya, Louizah Ochola, Telephorus Odawo, Patricia Odera Ojwang, Maureen Odhiambo, Ronald Odhiambo, Clevers Odhiambo, Leonard Odipo, Esther Odongo, Beatrice Odoyo, Kennedy Oduol, Charles Oduor, Kevin Ogamba, Willis Ogillo, Veronicah Okuna, Damaris Okwiri, Edwin Olweny, Dennis Omondi, Postine Omwalo, Mary Omwalo, Francis Orwa, Shaltone Osele, Benard Otero, Daniel Ouko, Felix Ouko, Diana Owera, Ann Owino, Faith Oyier, Linet Sewe, Martin Apgar, Mimi Campbell, Robin Carroll, Mike Castro, Jason Gall, Wesley Goss-Geffrard, Janel Holland-Linn, Yogita Jethmalani, Rachel Kazmierski, Richard A. Koup, Jeffery Liao, Kwang Low, Allen Mueller, Madeeha Mughal, Sandeep Narpala, Leigh Stephens, Laxmi Buyyani, Kanwaldeep Bajwa, Michael Holdsworth, Harish Kandaswamay, Diane Rock Kress, Mariam Namawejje, Pengchong Tang, Neelam Gulati, Liam Harmon, Shirley Jankelevich, Yvonne Jato, Aaren King, Stacy Kopka, Valerie Opher, John Tierney, Susan Vogel, Saran Wells, Kristin Young, Sammi Cheung, Annette M. Seilie, Weston Staubus, Ashley Subijanto

DOI

10.1016/s0140-6736(26)00258-8

PMID

42035777

PMCID

PMC13266303

OpenAlex

W7155420337

研究类型

Randomised controlled trial

出版商

Elsevier BV

文章类型

journal-article

完整性状态

current