Chronic hepatitis B is a long-standing infection with the hepatitis B virus, a DNA virus of the Hepadnaviridae family that replicates in hepatocytes and is usually defined by viral presence beyond six months [1][2]. It represents the chronic stage of hepatitis B and carries an elevated risk of liver disease and hepatocellular carcinoma [1][2].
Aperçu de la maladie
Informations étayées par des preuves EN 5/7 sections · FR 5/7 sections Mis à jour le Oct 23, 2026
Chronic hepatitis B is a persistent liver infection with the hepatitis B virus that follows acute exposure and is more likely when infection occurs at a younger age [1]. Most affected individuals remain without symptoms, though a substantial fraction progress to cirrhosis or liver cancer over time [1][2]. Public-health guidelines address its prevention and surveillance among specific risk groups [3].
Lire le profil clinique et épidémiologique complet 6
Many persons with chronic infection are asymptomatic, yet the condition can progressively lead to liver cirrhosis, which independently raises hepatocellular carcinoma risk [1][2]. Complications such as liver decompensation or carcinoma affect survival, and concurrent hepatitis D infection may worsen disease course [2].
In assisted reproductive technology, sperm washing is not necessary for males with hepatitis B to prevent transmission, unless the female partner has not been effectively vaccinated [1]. In females with hepatitis B, the risk of transmission from mother to child with IVF is no different from the risk in spontaneous conception [1]. Those at high risk of infection should be tested as there is effective treatment for those who have the disease [1]. Screening is recommended for unvaccinated persons from areas where hepatitis B occurs in more than 2%, those with HIV, intravenous drug users, and men who have sex with men [1].
The virus spreads through contact with infectious blood or body fluids [1]. In regions where hepatitis B is common, acquisition typically occurs around birth or through childhood blood contact, whereas in low-prevalence settings intravenous drug use and sexual intercourse dominate [1]. Prevention efforts target maternal-to-infant and horizontal transmission routes [3].
Guideline development addressed prevention of maternal-to-infant and horizontal transmission of chronic hepatitis B using structured evidence review [3]. In assisted reproduction, sperm washing is not required for hepatitis B-positive males unless the female partner lacks effective vaccination, and mother-to-child risk via IVF equals that of spontaneous conception [1]. Screening is recommended for unvaccinated persons from high-prevalence areas, those with HIV, intravenous drug users, and men who have sex with men [1].
- 1 Wikipedia contributors. Hepatitis B - Wikipedia [Internet]. Wikipedia. cited 4 Sept 2026. Available from: https://en.wikipedia.org/wiki/Hepatitis_B
- 2 Rizzo GEM et al. Hepatitis B Virus-Associated Hepatocellular Carcinoma. Viruses. 2022 May 7. PMID: 35632728. doi: 10.3390/v14050986. PubMed: https://pubmed.ncbi.nlm.nih.gov/35632728/
- 3 Ghany MG et al. AASLD ISDA Practice Guideline on treatment of chronic hepatitis B. Hepatology. 2026 Apr 1. PMID: 41186418. doi: 10.1097/HEP.0000000000001549. PubMed: https://pubmed.ncbi.nlm.nih.gov/41186418/
- B18.0-B18.1
- 1E51.0
Chargement des données actuelles…
Tendances nationales
Choisissez le pays, la source et la mesure ; chaque courbe conserve sa période et sa définition de déclaration.
Chargement des données…
Couverture des données
Pays et régions déclarants
La carte montre la couverture déclarée. Choisissez une mesure ou ouvrez un lieu coloré pour consulter ses données.
Chargement des données actuelles…
Profil de surveillance
Saisonnalité du pays sélectionné
Consultez les valeurs mensuelles d’un pays par année. Les cases vides indiquent une valeur non publiée.
Radar de recherche
Recherches récentes associées
Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance.
Journal of viral hepatitis
A Randomized, Double-Blind, Placebo-Controlled Study of the PD-1 Inhibitor Cetrelimab in Chronic Hepatitis B.
Journal of viral hepatitis
Dysregulated transcription in core- and pol-specific CD8 T cells can be targeted by HDAC inhibition to improve T-cell function in chronic hepatitis B
Journal of Hepatology
Évalué par les pairs Accès ouvert Association à vérifier Hépatite chronique B Dynamique de transmission
DOI 10.4254/wjh.124577 ↗ Risk factors and predictive model for hepatitis B virus deoxyribonucleic acid elevation in mid-to-late pregnancy with low viremia
World Journal of Hepatology
Évalué par les pairs Accès ouvert Association à vérifier Hépatite chronique B Dynamique de transmission
DOI 10.3389/fmicb.2026.1933288 ↗ Hepatitis B Immunoprophylaxis rarely prevents molecularly evident subclinical HBV infection in children born to HBsAg-positive mothers
Frontiers in Microbiology
5 publications associées sur 31 affichées.
Les liens bibliographiques servent à découvrir des travaux et ne modifient ni ne valident la série de surveillance ci-dessus.
Chargement des alertes officielles…
Téléchargement et méthodes
Choisissez une période et téléchargez les fichiers CSV, JSON ou XLSX.