Perinatal hepatitis C concerns infants or children who are exposed to hepatitis C virus during pregnancy or childbirth [1]. It is characterized as infection acquired around the perinatal period rather than through other routes [1][2].
Aperçu de la maladie
Informations étayées par des preuves EN 5/7 sections · FR 5/7 sections Mis à jour le Oct 23, 2026
Perinatal hepatitis C refers to HCV infection acquired by infants through exposure during pregnancy or childbirth, with maternal viremia serving as a recognized transmission risk [1][2]. Infection is often not clinically apparent in early infancy, underscoring the value of recommended testing to identify affected children [1]. Public-health guidance emphasizes antenatal testing and follow-up of exposed infants to avoid missed diagnoses [1].
Lire le profil clinique et épidémiologique complet 6
Infection may not be apparent in infancy, so testing is important to detect affected children and guide care [1]. Among children with perinatally acquired infection, spontaneous viral clearance occurs in a substantial proportion by age 5 years [1]. Although fetal infection was historically described as asymptomatic, isolated fetal ascites has been reported as a possible sole presenting sign in some HCV-exposed fetuses [2].
Maternal detectable HCV RNA is a known risk factor for perinatal transmission, and public-health recommendations address testing of exposed children [1]. Transmission from a viremic pregnant person to the infant at delivery occurs in an estimated 4%–7% of such cases [2]. Spontaneous clearance among perinatally infected children has been observed in roughly 20%–40% by age 5 years in earlier summaries, with more recent analyses suggesting clearance in the majority by that age [1].
HCV can pass from a pregnant person with viremic infection to an infant around birth, with delivery and exposure factors influencing risk [1]. Documented perinatal transmission rates are 4%–7% when detectable viremia is present at delivery [2]. Intrauterine transmission has also been suspected as a cause of isolated fetal ascites in the absence of other explanations [2].
Prevention of perinatal hepatitis C involves hepatitis C testing during pregnancy, appropriate pregnancy and delivery management, and timely testing of perinatally exposed infants to support prevention of missed infection and later complications [1].
- 1 US Centers for Disease Control and Prevention. CDC Recommendations for Hepatitis C Testing Among Perinatally Exposed Infants and Children â United States, 2023 | MMWR [Internet]. cited 23 Oct 2026. Available from: https://www.cdc.gov/mmwr/volumes/72/rr/rr7204a1.htm
- 2 Rădoi CL et al. Intrauterine Transmission of Hepatitis C Virus Concomitant with Isolated Severe Fetal Ascites. Pathogens. 2022 Nov 12. PMID: 36422587. doi: 10.3390/pathogens11111335. PubMed: https://pubmed.ncbi.nlm.nih.gov/36422587/
Chargement des données actuelles…
Tendances nationales
Choisissez le pays, la source et la mesure ; chaque courbe conserve sa période et sa définition de déclaration.
Chargement des données…
Couverture des données
Pays et régions déclarants
La carte montre la couverture déclarée. Choisissez une mesure ou ouvrez un lieu coloré pour consulter ses données.
Chargement des données actuelles…
Profil de surveillance
Saisonnalité du pays sélectionné
Consultez les valeurs mensuelles d’un pays par année. Les cases vides indiquent une valeur non publiée.
Chargement des alertes officielles…
Téléchargement et méthodes
Choisissez une période et téléchargez les fichiers CSV, JSON ou XLSX.