Current global trends in meningococcal disease control, risk groups and vaccination: Consensus of the Global Meningococcal Initiative
Journal of Infection·
- DOI
- 10.1016/j.jinf.2025.106635
- PMID
- 41110781
- PMCID
- —
- OpenAlex
- W4415292308
- Study type
- Guideline
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
These observations underscore evolving transmission patterns and atypical disease manifestations that may necessitate adjustments to routine immunization schedules and travel-related health advisories.
Structured evidence summary
Research question
The document examines worldwide epidemiological shifts in invasive meningococcal illness alongside updated strategies for pathogen control and immunization coverage.
Study design
The publication functions as a peer-reviewed consensus review and guideline synthesizing expert discussions from an international initiative.
Population and setting
The analysis encompasses broad international cohorts, with specific references to travelers visiting Saudi Arabia, national populations in the United States, and clinical cases observed in France.
Main findings
Authors note a resurgence of a specific serogroup W lineage associated with regional travel, alongside rising annual infection counts across multiple nations following recent global health disruptions. The review also documents a surge in unusual clinical forms such as throat inflammation in European settings and advocates for expanded immunization programs targeting multiple bacterial strains, while acknowledging preliminary data suggesting possible cross-protection against another sexually transmitted pathogen.
Public-health relevance
These observations underscore evolving transmission patterns and atypical disease manifestations that may necessitate adjustments to routine immunization schedules and travel-related health advisories.
Important limitations
The provided summary relies exclusively on the supplied abstract and bibliographic metadata, requiring examination of the complete manuscript to fully evaluate methodological constraints and interpretive boundaries for decision-making purposes.
GIDS interpretation
This record offers contextual background regarding historical pathogen circulation and policy deliberations surrounding meningococcal prevention, serving as a reference for literature mapping rather than an indicator of active community transmission.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 15 auditable classifier relationships to diseases, places, topics, and study design.