Global misinformation, local consequences: conspiracy theory endorsement and a graded association with COVID-19 vaccine refusal across Nigeria
Vaccine·
- DOI
- 10.1016/j.vaccine.2026.128827
- PMID
- 42308979
- PMCID
- —
- OpenAlex
- W7164943986
- Study type
- Cross-sectional study
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
Documenting the strength of misinformation-driven immunization reluctance in a resource-limited context underscores the potential utility of tailored communication approaches for upcoming health crises.
Structured evidence summary
Research question
How does endorsement of COVID-19 vaccine conspiracy narratives relate to immunization reluctance among Nigerian adults?
Study design
A peer-reviewed cross-sectional survey employing convenience sampling of adults across Nigeria, with statistical analysis performed using multivariable logistic regression.
Population and setting
Adult respondents selected via convenience sampling spanning all six geopolitical zones of Nigeria during a phase of sustained low national immunization rates.
Main findings
Most respondents demonstrated hesitancy and supported at least one false narrative, particularly regarding tracking devices. Incremental increases in conspiracy belief corresponded to markedly decreased likelihood of vaccine acceptance, surpassing the influence of standard demographic variables.
Public-health relevance
Documenting the strength of misinformation-driven immunization reluctance in a resource-limited context underscores the potential utility of tailored communication approaches for upcoming health crises.
Important limitations
The convenience sampling approach and reliance on self-reported interview responses may restrict broader applicability and introduce reporting bias. Because the provided materials lack explicit methodological caveats, this evaluation rests entirely on the supplied abstract and metadata, necessitating full-text examination for rigorous appraisal.
GIDS interpretation
This record offers regional context regarding information dissemination patterns and immunization attitudes, which can support bibliographic mapping efforts without implying integration into active epidemiological tracking systems.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 10 auditable classifier relationships to diseases, places, topics, and study design.