COVID-19 vaccination among people with HIV in Uganda: lessons from a high-risk group with high vaccine uptake for the next pandemic
Vaccine·
- DOI
- 10.1016/j.vaccine.2026.128912
- PMID
- 42430873
- PMCID
- —
- OpenAlex
- W7167934159
- Study type
- Cohort study
- Publisher
- Elsevier BV
- Article type
- journal-article
- Integrity
- current
Why this research matters now
Sustaining elevated protection levels in this clinical subgroup requires targeted communication strategies that address safety perceptions and counteract inaccurate health information.
Structured evidence summary
Research question
The investigation evaluates determinants influencing coronavirus disease 2019 immunization and identifies primary obstacles to acceptance among individuals managing human immunodeficiency virus infection in a Ugandan urban center.
Study design
Researchers conducted a cross-sectional evaluation utilizing baseline data extracted from an ongoing longitudinal cohort.
Population and setting
The enrolled sample consisted of four hundred forty-nine adults receiving continuous antiretroviral treatment residing in Mbarara, Uganda.
Main findings
Immunization coverage reached substantial levels across the participating group. Individuals who declined the injection primarily cited concerns regarding product safety rather than logistical or access-related obstacles.
Public-health relevance
Sustaining elevated protection levels in this clinical subgroup requires targeted communication strategies that address safety perceptions and counteract inaccurate health information.
Important limitations
The analytical framework relies on a single timepoint assessment, which restricts the ability to establish temporal relationships between identified variables and immunization decisions.
GIDS interpretation
This record contributes to the broader literature on regional immunization behaviors and can assist automated systems in categorizing publications related to viral prophylaxis and chronic infection management without implying real-time outbreak monitoring.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 13 auditable classifier relationships to diseases, places, topics, and study design.