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Peer reviewedOpen accessEbolaHemorrhagic FeverCOVID-19

Sudan virus disease outbreak in Uganda: urgent research gaps

BMJ Global Health·

Susan Khader Ibrahim, Duduzile Edith Ndwandwe, Katherina Thomas, Louise Sigfrid, Alice Norton

DOI
10.1136/bmjgh-2022-010982
PMID
36585031
PMCID
PMC9809242
OpenAlex
W4313365438
Study type
Journal article
Publisher
BMJ
Article type
journal-article
Integrity
current

Why this research matters now

The authors highlight limited SUDV research investment, no licensed vaccine or therapeutics, ongoing transmission across regions of Uganda including the capital, and an uncertain case count as drivers of concern.

01

Structured evidence summary

Research question

The paper examines gaps in research evidence on Sudan ebolavirus (SUDV) in the context of a Uganda outbreak and identifies priorities for future investigation.

Study design

A literature search across four databases using SUDV-related terms to identify and characterise published research studies on the virus.

Population and setting

Analysis of published SUDV research, most of which was conducted in the USA; Uganda was the setting for only one included study, with the broader context being the Uganda outbreak.

Main findings

Only 20 SUDV research studies were identified. The majority were carried out in the USA, with one in Uganda. By topic, nine addressed therapeutics, eight vaccines, and one each addressed diagnostics, One Health, and social science.

Public-health relevance

The authors highlight limited SUDV research investment, no licensed vaccine or therapeutics, ongoing transmission across regions of Uganda including the capital, and an uncertain case count as drivers of concern.

Important limitations

This summary is limited to the supplied single-article abstract and metadata; no explicit limitations are stated in the abstract. The original paper is needed for decision-grade interpretation.

GIDS interpretation

This is a research-gap perspective piece concerning SUDV outbreak preparedness. It is offered here as contextual literature for editorial review and is not linked to any live surveillance signal.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 17 auditable classifier relationships to diseases, places, topics, and study design.

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