Global search

Find data and evidence

Type at least 2 characters. Use arrow keys to review and Enter to open.

Public-health topic

Vaccine safety

Published Research Radar records connected to the Vaccine safety topic through the auditable classification pipeline.

Published evidence
377
Diseases
63
Countries
71
Topics
13

Evidence stream

Published literature

377

30 of 377 publications shown

Short-term adverse events following modified vaccinia Ankara–Bavarian Nordic (MVA-BN) mpox vaccine with and without concomitant vaccines, Australia, 2022 to 2023

Thuy Nguyen, Kristine Macartney, Nicholas Wood +2 more

Eurosurveillance

Type
Journal article
Scope
Australia

Why it matters now The findings may inform future immunisation policy and public-health recommendations concerning co-administration of MVA-BN with other adult vaccines, particularly in adult men. The abstract describes this relevance as preliminary and exploratory.

Efficacy of WRSs2, a live-attenuated Shigella sonnei vaccine, against shigellosis in a controlled human infection model in the USA: a phase 2, double-blind, randomised, placebo-controlled trial

Nadine Rouphael, Shahida Baqar, Michelle Dickey +35 more

The Lancet Infectious Diseases

Type
Randomised controlled trial
Scope
United States

Why it matters now Shigella is a leading cause of bacterial diarrhoea and dysentery worldwide, and no licensed vaccine currently exists. The trial results support further clinical development of live-attenuated shigella vaccines.

Peer reviewed Open access ZosterHIV infection VaccinationTreatmentVaccine safety
DOI 10.1016/j.ijid.2026.109100 ↗

Impact of CD4 T cell counts on the immunogenicity and safety of the recombinant zoster vaccine in people living with HIV

Min-Kyung Kim, Hyeon Jae Jo, Chan Mi Lee +10 more

International Journal of Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters now RZV produced strong antibody responses in PLWH irrespective of CD4 count, but cell-mediated responses were weaker than in HIV-negative people, informing vaccine expectation in this group.

What a highly monitored chikungunya epidemic reveals about preparedness for Europe and beyond.

Mosnier E, Gérardin P, D'Ortenzio E +3 more

Archives of public health = Archives belges de sante publique

Type
Journal article
Scope
Not classified

Why it matters now The account underscores the difficulty of converting early warnings into rapid action and supports integrated preparedness planning for arboviral threats.

Peer reviewed Open access DengueArboviral diseases VaccinationVaccine safety
DOI 10.3390/vaccines14100902 ↗

Immunological Challenges and Emerging Strategies in Dengue Virus Vaccine Development

Xuelian Ma, Mengyuan Zhao, Yaqun Xu +4 more

Vaccines

Type
Journal article
Scope
Brazil

Why it matters now Dengue is a rapidly spreading arboviral disease; the review provides a strategic reference for safer and more effective next-generation vaccines.

Enhanced passive safety surveillance (EPSS) of a seasonal intranasal influenza vaccine (Fluenz® Tetra) in children in England: methodology, results and lessons learned from eight influenza seasons (2015/2016 to 2022/2023)

Sandeep Dhanda, Denise E Morris, Kathryn Morton +2 more

Vaccine

Type
Journal article
Scope
United Kingdom

Why it matters now The EPSS methodology provided near real-time, patient-reported safety data with denominator-based risk estimates, serving as a complement to routine pharmacovigilance for an intranasal paediatric influenza vaccine used in the UK programme.

Peer reviewed Open access COVID-19SARS VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.129046 ↗

Overestimation of racial ingroup worry about the COVID-19 vaccine and medical racism

Samantha L. Heiman, Nathaniel Geiger

Vaccine

Type
Journal article
Scope
United States

Why it matters now The findings describe group-level perceptions surrounding COVID-19 vaccine safety, perceived rights violations, medical racism, and related misinformation. They may provide context for interpreting communication and opinion research about vaccination, but the abstract does not establish effects on vaccination behavior or population-level outcomes.

Peer reviewed Open access COVID-19SARS VaccinationVaccine safety
DOI 10.1186/s13010-026-00232-3 ↗

Beyond correlation and causation: epistemic caution, anomalous findings, and COVID-19 vaccine safety.

Siebner AS, Rubio-Casillas A, Raszek M +7 more

Philosophy, ethics, and humanities in medicine : PEHM

Type
Journal article
Scope
Not classified

Why it matters now The article is relevant to vaccine safety review because it addresses how possible adverse events may be investigated when causality is uncertain. Its relevance is framed around COVID-19 vaccination, epistemic caution, and interpretation of anomalous safety findings.

Peer reviewed Open access COVID-19Influenza VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.129126 ↗

Gaps between willingness and uptake of influenza and COVID-19 vaccines during the 2025–26 respiratory virus season in a U.S. adult cohort

Jenna Sanborn, McKaylee M. Robertson, Kate Penrose +4 more

Vaccine

Type
Journal article
Scope
United States

Why it matters now The findings highlight missed opportunities among adults with prior or stated openness to vaccination and suggest strategies to improve coverage by reinforcing vaccine confidence, reducing access and logistical barriers, and facilitating vaccination completion.

Peer reviewed Open access COVID-19SARS VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.129122 ↗

Self-reported reactogenicity after COVID-19 vaccination with and without influenza vaccine coadministration during pregnancy in Canada

Sophie Tran, Elisabeth McClymont, Sandra Blitz +28 more

Vaccine

Type
Journal article
Scope
Canada

Why it matters now Findings support counseling messages that same-day COVID-19 and influenza vaccination during pregnancy is generally well-tolerated, which may inform communication aimed at reducing vaccine hesitancy during seasonal overlap.

Peer reviewed Open access PertussisDiphtheria VaccinationVaccine safety
DOI 10.1016/s1473-3099(26)00470-6 ↗

Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, evaluated with and without tetanus-reduced diphtheria-acellular pertussis vaccine in healthy children aged 6–17 years: a randomised, active-controlled and placebo-controlled, phase 2b trial

Saul N Faust, Javier Céspedes, Lydiana Ávila +42 more

The Lancet Infectious Diseases

Type
Journal article
Scope
Australia, Costa Rica, United Kingdom

Why it matters now The abstract frames pertussis as an ongoing public health concern and describes BPZE1 as a candidate intended to induce mucosal immune responses. The reported findings support further development of this candidate in acellular pertussis vaccine-primed children aged 6 years and older.

Peer reviewed Open access MumpsRubella VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.129168 ↗

The risk of idiopathic thrombocytopenic purpura after first and second measles, mumps, rubella (MMR) vaccine doses in children born in England 2000–2019

Nick Andrews, Julia Stowe, Erjola Hani +2 more

Vaccine

Type
Journal article
Scope
Myanmar

Why it matters now Findings indicate MMR dose two is safe for children who had ITP after dose one, supporting continued vaccination practice.

Knowledge as a predictor of parental vaccine hesitancy during children's first year of life

Malena Gonçalves Almeida, Beatriz Fátima Alves de Oliveira, Eugênio Barbosa de Melo Júnior +5 more

Vaccine

Type
Journal article
Scope
Not classified

Why it matters now Substantial caregiver hesitancy in early infancy, especially for COVID-19, suggests that improving vaccine knowledge may support adherence in this age group.

Peer reviewed Open access InfluenzaHIV infection VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.129166 ↗

Immunogenicity and safety of high-dose versus standard-dose quadrivalent inactivated influenza vaccine in patients living with HIV: a randomized controlled trial

Nutchaya Laoharattanahirun, Sasisopin Kiertiburanakul, Kobporn Boonnak +1 more

Vaccine

Type
Randomised controlled trial
Scope
Not classified

Why it matters now The abstract frames influenza as a major cause of morbidity in people living with HIV and notes that standard-dose vaccine responses are often suboptimal in this population.

Peer reviewed Open access Hepatitis BCOVID-19 VaccinationSurveillanceVaccine safety
DOI 10.7759/cureus.117224 ↗

Serious and Non-serious Hepatitis Reports in the U.S. Vaccine Adverse Event Reporting System, 1990-2026: A Cross-Sectional Analysis.

Aragón Gutierrez P, Botlaguduru D, Chowdary Medarametla A +1 more

Cureus

Type
Cross-sectional study
Scope
United States

Why it matters now The study provides descriptive context on hepatitis reports submitted to a U.S. vaccine adverse-event reporting system and identifies differences in seriousness classification across age groups. The abstract does not support estimates of vaccine-specific risk or incidence, causal attribution, or a clinical or policy recommendation.

Peer reviewed Open access PertussisDiphtheria VaccinationSurveillanceVaccine safety
DOI 10.3389/fcimb.2026.1831548 ↗

Post-marketing safety surveillance of tetanus, diphtheria, and acellular pertussis (Tdap) vaccine: a disproportionality analysis of the vaccine adverse event reporting system (2015–2025)

Wenyan Song, Hongjun Chen, Meiyan Wang +1 more

Frontiers in Cellular and Infection Microbiology

Type
Journal article
Scope
United States

Why it matters now The paper addresses post-marketing vaccine safety surveillance for a routinely recommended vaccine. Its relevance is strongest for safety signal detection and hypothesis generation in Tdap vaccination programs.

Peer reviewed Open access COVID-19SARS VaccinationVaccine safety
DOI 10.1016/j.ijid.2026.108886 ↗

Pregnant Women COVID-19 immunisation in 2026: evidence, uncertainty and priorities

Odile Launay, Olivia Anselem, Pradip Dashraath +2 more

International Journal of Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters now Suboptimal vaccine uptake during pregnancy represents a continuing public health challenge. Clarifying evidence, addressing uncertainties, and identifying priorities may support improved maternal immunization programs.

Strengthening public understanding and prevention of dengue in Malaysia: insights and recommendations based on knowledge, attitudes, and practices toward vector control and vaccination

Asrul Akmal Shafie, Zulkifli Ismail, Ken Yong +3 more

Frontiers in Public Health

Type
Cross-sectional study
Scope
Malaysia

Why it matters now Identifying specific informational gaps and behavioral barriers supports the development of focused outreach initiatives. Aligning communication strategies with established community trust networks could enhance engagement with integrated disease management approaches.

Real-world analysis of depression-related adverse events associated with the adsorbed anthrax vaccine: integrating pharmacovigilance signals, machine learning risk prediction, and transcriptomic mechanisms

Guangwei Qing, Yimei Zhao, Jian Yang +1 more

Infectious Diseases of Poverty

Type
Journal article
Scope
United States

Why it matters now The documented reporting patterns indicate a rationale for strengthening psychiatric symptom tracking during post-vaccination windows and refining safety communications within biodefense preparedness programs.

V-safe: Summary of findings reported after COVID-19 vaccination to a US CDC active safety surveillance system through June 2023

Tanya R. Myers, Lauren H. Zauche, Paige L. Marquez +3 more

Vaccine

Type
Journal article
Scope
United States

Why it matters now Continuous tracking of self-reported tolerability complements traditional clinical trial metrics and supports ongoing evaluation of emerging immunization products. Identifying engagement drop-offs informs strategy development for sustaining participant involvement during future public health emergencies.

Safety and immunogenicity testing of a melioidosis subunit vaccine candidate in cynomolgus macaques

Sineenart Sengyee, Caitlyn E. Orne, Sarah B. Weiby +8 more

npj Vaccines

Type
Journal article
Scope
Not classified

Why it matters now The results support continued development of the vaccine candidate toward a human clinical trial, but the evidence does not establish human safety or efficacy.

Peer reviewed Open access COVID-19SARS VaccinationVaccine safety
DOI 10.1093/cid/ciag344 ↗

Immunogenicity and Safety of Coadministration of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine and a COVID-19 mRNA Vaccine in Adult s Aged ≥50 Years: A Phase 3, Randomized, Noninferiority Trial

Marc Bonten, Brandon Essink, Nikita Hanning +11 more

Clinical Infectious Diseases

Type
Journal article
Scope
Not classified

Why it matters now Findings indicate that concurrent RSV and COVID-19 mRNA vaccination in older adults is feasible with an acceptable safety profile, potentially simplifying seasonal immunization delivery.

Peer reviewed Open access Typhoid feverParatyphoid fever VaccinationTreatmentVaccine safety
DOI 10.1016/s1473-3099(25)00730-3 ↗

Safety and immunogenicity of a conjugate vaccine candidate against Salmonella enterica serovars Typhi and Paratyphi A in healthy adults in Europe: a phase 1 randomised controlled trial

Ilse De Coster, Mohammad AbdelGhany, Eleanna Sarakinou +18 more

The Lancet Infectious Diseases

Type
Randomised controlled trial
Scope
Belgium

Why it matters now Findings support further clinical assessment of the full-dose formulation without aluminium hydroxide in populations such as infants and older age groups in endemic regions, addressing the absence of licensed vaccines against Salmonella Paratyphi A.

MVA-BN monkeypox vaccine safety in a clinical trial in the Democratic Republic of the Congo

Nsengi Ntamabyaliro, Tyler Bonnett, Gail Potter +18 more

npj Vaccines

Type
Journal article
Scope
Democratic Republic of the Congo

Why it matters now The findings provide additional evidence from an endemic setting that the MVA-BN vaccine, widely deployed for monkeypox prevention, is generally safe and well-tolerated with predominantly mild injection site reactions.

Efficacy of ProC6C-AlOH/Matrix-M against Plasmodium falciparum infection and mosquito transmission: a phase 2, randomised, controlled human malaria infection study

Mamady Kone, Jordan Plieskatt, Moussa Thienta +31 more

The Lancet Infectious Diseases

Type
Randomised controlled trial
Scope
Mali

Why it matters now The product is the first anti-PfCSP subunit vaccine with over 50% efficacy versus controlled challenge at 12 weeks, supporting further trials in young children against natural malaria.

Safety and immunogenicity of PanChol, a single-dose live-attenuated oral cholera vaccine: results from a phase 1a, double-blind, randomised, placebo-controlled trial

Deborah R Leitner, Stephen R Walsh, Masataka Suzuki +28 more

The Lancet Infectious Diseases

Type
Randomised controlled trial
Scope
United States

Why it matters now The results support advancing PanChol to later-phase trials, including in endemic areas and children, as a potential single-dose alternative to multi-dose killed vaccines.

Peer reviewed Open access COVID-19Influenza VaccinationVaccine safety
DOI 10.1016/j.vaccine.2026.128569 ↗

Safety of seasonal inactivated influenza vaccines in children 6 months–17 years of age in the Vaccine Adverse Events Reporting System (VAERS) 2018–2023: before, during, and after the COVID-19 pandemic public health emergency

E. Gloria Anyalechi, Paige L. Marquez, Mary N. Rubin +9 more

Vaccine

Type
Journal article
Scope
Not classified

Why it matters now Findings support continued seasonal influenza vaccination in children by showing a consistent and non-alarming safety profile in VAERS during and around the pandemic.

Immunogenicity and safety of MF59-adjuvanted H5N1 pandemic influenza vaccine in healthy infants and children: a phase 2 randomized, observer-blind, multicenter study

Airi Põder, Mitzi Trinidad-Aseron, Esther Van Twuijver +2 more

Vaccine

Type
Randomised controlled trial
Scope
Not classified

Why it matters now Zoonotic H5N1 influenza may severely affect children; the study offers candidate pediatric vaccine data for pandemic preparedness.

Self-reported reactogenicity of RSV vaccines among older adults: a post-licensure study within a large integrated healthcare system in Southern California

Debbie E. Malden, Bradley K. Ackerson, Julianne Gee +9 more

Vaccine

Type
Journal article
Scope
Not classified

Why it matters now Findings show RSV vaccine reactions are mostly transient and seldom need medical attention, supporting post-marketing safety monitoring using surveys and records.

Evaluation of Rift Valley fever vaccine candidates in pregnant rodent models

Cigdem Alkan, Eduardo Jurado-Cobena, Tetsuro Ikegami

Vaccine

Type
Journal article
Scope
Not classified

Why it matters now Findings may help guide later refinement of RVFV vaccine safety assessment for pregnancy by indicating which animal model reveals placental tropism.