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Peer reviewedOpen accessQ fever

Q fever endocarditis of the tricuspid valve transmitted in an urban setting with no livestock exposure: Case report

BMC Infectious Diseases·

Dirk Habedank, Angelika Bublak, Birgit Habedank

DOI
10.1186/s12879-024-09629-x
PMID
39090536
PMCID
PMC11293036
OpenAlex
W4401225081
Study type
Journal article
Publisher
Springer Science and Business Media LLC
Article type
journal-article
Integrity
current

Why this research matters now

The case demonstrates that Q fever infection can occur in non-rural, urban settings without traditional livestock exposure, suggesting alternative transmission pathways may warrant surveillance attention.

01

Structured evidence summary

Research question

The authors describe a case of Q fever endocarditis affecting the tricuspid valve in a patient with no livestock contact, acquired in an urban setting.

Study design

This is a single case report describing clinical presentation, epidemiological investigation, laboratory confirmation, and treatment outcome.

Population and setting

The patient was a previously healthy 55-year-old man working as a cemetery gardener in Berlin, Germany. Exposure occurred in a metropolitan area with no sheep contact but with close temporal and local exposure to wild boar.

Main findings

The patient developed confirmed Coxiella burnetii endocarditis of the tricuspid valve following exposure in a strictly urban environment. The infection was laboratory-confirmed by the German Reference Laboratory. The patient achieved complete recovery after treatment with doxycycline and hydroxychloroquine.

Public-health relevance

The case demonstrates that Q fever infection can occur in non-rural, urban settings without traditional livestock exposure, suggesting alternative transmission pathways may warrant surveillance attention.

Important limitations

This summary is limited to the supplied single-article abstract and bibliographic metadata. The case report describes a single patient and does not establish a transmission pathway definitively. Full interpretation requires access to the complete published article.

GIDS interpretation

The article was classified under Q fever, transmission dynamics, travel medicine, and treatment. It describes an atypical urban case that may inform case investigation protocols where traditional livestock exposure is absent.

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Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

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Evidence relationships

This article has 8 auditable classifier relationships to diseases, places, topics, and study design.

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