Molecular detection of pathogens associated with childhood gastroenteritis in Burkina Faso using the FilmArray® GI panel
BMC Infectious Diseases·
- DOI
- 10.1186/s12879-026-14002-1
- PMID
- 42443776
- PMCID
- —
- OpenAlex
- W7168175046
- Study type
- Journal article
- Publisher
- Springer Science and Business Media LLC
- Article type
- journal-article
- Integrity
- current
Publication version
This article has a linked preprint
The relationship comes from Crossref version metadata. Compare both records because findings and wording may have changed between versions.
Open linked preprint →Why this research matters now
The study describes pathogen distribution in childhood diarrhea in a low-income setting and reports that multiplex PCR testing supported broad pathogen detection in this population.
Structured evidence summary
Research question
The study investigated the epidemiology of infectious agents responsible for acute gastroenteritis in hospitalized children under five years of age at a single hospital in Burkina Faso.
Study design
A prospective, descriptive study conducted from December 2017 to November 2018, analyzing stool samples from 90 hospitalized children under five years of age using the FilmArray GI panel for 22 pathogens.
Population and setting
Ninety hospitalized children under five years of age presenting with acute gastroenteritis at Bogodogo University Hospital in Burkina Faso.
Main findings
At least one pathogen was detected in 74.4% of patients, with co-infections slightly more common than single-pathogen infections. Viruses and bacteria were each detected in 58.8% of cases and parasites in 30%. The most frequently detected pathogen was diarrheagenic E. coli (48.8%), followed by rotavirus (22.2%) and Giardia lamblia (16.6%).
Public-health relevance
The study describes pathogen distribution in childhood diarrhea in a low-income setting and reports that multiplex PCR testing supported broad pathogen detection in this population.
Important limitations
The summary is limited to the supplied single-article abstract and bibliographic metadata, and the original paper is needed for decision-grade interpretation; no explicit limitations were stated in the abstract.
GIDS interpretation
The article is thematically relevant to enteric pathogen surveillance in West Africa and may inform context for GIDS-style discoverability queries; the abstract alone does not establish a live surveillance signal connection.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 7 auditable classifier relationships to diseases, places, topics, and study design.