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Peer reviewedOpen accessTuberculosis

Evaluation of a social protection policy on tuberculosis treatment outcomes: A prospective cohort study

PLOS Medicine·

Karen Klein, Maria Paula Bernachea, Sarah Irribarren, Luz Gibbons, Cristina Chirico, Fernando Rubinstein

DOI
10.1371/journal.pmed.1002788
PMID
31039158
PMCID
PMC6490910
OpenAlex
W2943612867
Study type
Cohort study
Publisher
Public Library of Science (PLoS)
Article type
journal-article
Integrity
current

Why this research matters now

The authors suggest the cash transfer policy may be a useful intervention to improve tuberculosis treatment outcomes in similar high-burden settings.

01

Structured evidence summary

Research question

The study assessed whether a conditional cash transfer policy affects tuberculosis treatment success and default rates among socioeconomically disadvantaged adults.

Study design

A prospective cohort of first-diagnosis pulmonary tuberculosis patients was followed through treatment, with analyses using hierarchical models, propensity score matching, and inverse probability weighting to adjust for individual and health-system confounders.

Population and setting

Adult patients with a first pulmonary tuberculosis diagnosis starting treatment at public healthcare facilities in 16 high-burden health departments in Buenos Aires, Argentina.

Main findings

Among 941 patients with known status, those registered for the cash transfer had higher reported success (82% vs 69%) and lower default (11% vs 20%). The reported adjusted odds ratio for treatment success was 2.9 (95% CI 2.0–4.3).

Public-health relevance

The authors suggest the cash transfer policy may be a useful intervention to improve tuberculosis treatment outcomes in similar high-burden settings.

Important limitations

The summary is limited to the supplied single-article abstract and metadata; the original paper is needed for decision-grade interpretation, including assessment of residual confounding, representativeness, and outcome definitions.

GIDS interpretation

The paper is indexed under tuberculosis, Argentina, health policy, and treatment-related classifiers, which may aid discoverability by users searching for socioeconomic interventions and TB outcomes in Latin America.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 11 auditable classifier relationships to diseases, places, topics, and study design.

about diseaseaddresses topicaddresses topicaddresses topicaddresses topicevaluates interventioninforms policy domainstudied instudied population settingstudies populationuses study design