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Peer reviewedOpen accessEchinococcosis

Cardiac cystic echinococcosis—A systematic review and analysis of the literature

PLOS Neglected Tropical Diseases·

Simone Bumann, Esther Kuenzli, Raffaella Lissandrin, Enrico Brunetti, Sam Goblirsch, Lars Henning, Francesca Tamarozzi, Andreas Neumayr

DOI
10.1371/journal.pntd.0012183
PMID
38814859
PMCID
PMC11139302
OpenAlex
W4399171418
Study type
Systematic review
Publisher
Public Library of Science (PLoS)
Article type
journal-article
Integrity
current

Why this research matters now

This paper is relevant as a consolidated source on a rare form of cystic echinococcosis that can affect cardiac function and may require prolonged follow-up after treatment. It is useful for editorial context on diagnosis and management, not as evidence of a live surveillance signal.

01

Structured evidence summary

Research question

To synthesize published evidence on the anatomical, clinical, diagnostic, and treatment features of cardiac cystic echinococcosis.

Study design

Systematic review of literature published from 1965 to 2022.

Population and setting

Published cases of human cardiac cystic echinococcosis reported in the medical literature. No country or single clinical setting was specified in the supplied abstract.

Main findings

The review reports that cardiac involvement is uncommon, but published cases continue to accumulate. Most patients were symptomatic, common complaints were non-specific cardiopulmonary symptoms, and acute events were mainly linked to cyst rupture. Imaging was described as the main diagnostic approach, surgery was the usual treatment, and the review estimated disease-related fatality at 11.1%.

Public-health relevance

This paper is relevant as a consolidated source on a rare form of cystic echinococcosis that can affect cardiac function and may require prolonged follow-up after treatment. It is useful for editorial context on diagnosis and management, not as evidence of a live surveillance signal.

Important limitations

The abstract states that cardiac CE is rare and that the lack of clinical trials limits knowledge. The summary is also constrained by reliance on the supplied single-article abstract and metadata rather than the full paper.

GIDS interpretation

This article is discoverable as a systematic synthesis of historical published cardiac CE cases and can provide background context for editorial review. It does not establish a current outbreak, trend, or surveillance-confirmed signal.

02

Related GIDS surveillance

Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.

03

Evidence relationships

This article has 8 auditable classifier relationships to diseases, places, topics, and study design.

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