Outbreak of Mycobacterium orygis in a Shipment of Cynomolgus Macaques Imported from Southeast Asia — United States, February–May 2023
MMWR. Morbidity and Mortality Weekly Report·
- DOI
- 10.15585/mmwr.mm7307a2
- PMID
- 38386802
- PMCID
- PMC10899076
- OpenAlex
- W4392034787
- Study type
- Journal article
- Publisher
- Centers for Disease Control MMWR Office
- Article type
- journal-article
- Integrity
- current
Why this research matters now
The report is relevant to import quarantine, biosafety practices, and oversight of nonhuman primate movements tied to zoonotic disease risk. It is also positioned as an outbreak investigation with One Health implications.
Structured evidence summary
Research question
The article examines detection and response to an outbreak of tuberculosis caused by Mycobacterium orygis in imported cynomolgus macaques. It also frames the event in terms of quarantine screening and occupational risk during importation for research use.
Study design
This is a journal article reporting an outbreak investigation and public health response. The abstract indicates CDC collaboration with the importer and USDA laboratory partners during quarantine screening and follow-up.
Population and setting
The affected population was a shipment of 540 cynomolgus macaques imported from Southeast Asia to the United States for research purposes. The setting also included CDC-mandated quarantine and the transport/quarantine workforce in the United States.
Main findings
The outbreak was detected during CDC-mandated quarantine, and 26 macaques had culture-positive results for M. orygis. The abstract also states that no cases were identified among caretakers in the United States.
Public-health relevance
The report is relevant to import quarantine, biosafety practices, and oversight of nonhuman primate movements tied to zoonotic disease risk. It is also positioned as an outbreak investigation with One Health implications.
Important limitations
The summary is limited to the supplied single-article abstract and bibliographic metadata, so it cannot support decision-grade interpretation without the full paper. The abstract does not provide detailed methods, analytic depth, or full case definitions.
GIDS interpretation
This article is discoverable as an outbreak investigation involving imported animals, quarantine screening, and occupational protection measures. It should be treated as a contextual source about an investigated event, not as live surveillance confirmation.
Related GIDS surveillance
Literature context does not validate, explain, or change a surveillance signal. Exact and contextual relationships are shown separately.
Evidence relationships
This article has 7 auditable classifier relationships to diseases, places, topics, and study design.